Maternal and Pediatric Precision in Therapeutics (MPRINT) Knowledge and Research Coordination Center

<p>The <i>Eunice Kennedy Shriver National Institute of Child Health and Human Development</i> (NICHD) intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications to establish a Knowledge and Research Coordination Center as part of the NICHD’s Maternal and Pediatric Precision in Therapeutics (MPRINT) Hub. The MPRINT KRCC will accelerate safe, effective drug development and regulatory science through expanding the available knowledge, tools, and expertise in maternal and pediatric therapeutics by: (1) Developing an easily queryable curated and interoperable pharmacology knowledgebase; (2) Leveraging real-world clinical data and insights, particularly through mother-baby linkages; (3) Supporting and leveraging efficient and innovative clinical trials in pediatrics, obstetrics, and lactation; (4) Uniting multidisciplinary expertise and training the future workforce. The Center will collaborate with MPRINT’s Maternal Medication and Human Milk Research Center (M2HMRC)&nbsp;to conduct cutting-edge clinical, translational, and data science research. Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will support cooperative agreements involving large-scale research activities with complex structures.</p><p>Grant authorities that allow the Eunice Kennedy Shriver National Institute of Child Health and Human Development&nbsp;to forecast this opportunity are as follows: Public Health Service Act, Section 301, 448 and 487, as amended, Public Laws 78-410 and 99-158, as amended, 42 U.S.C. 241; 42 U.S.C. 285g; 42 U.S.C. 288; Small Business Research and Development Enhancement Act of 1992, Public Law 102-564, Public Law 118-47.</p>