Division of Chemical Toxicology Symposia at the 270th National ACS meeting

The goal of this application is to obtain support for the American Chemical Society Division of Chemical Toxicology (TOXI) at the 270th National Meeting, scheduled for August 17-21, 2025, in Washington, DC. The Division's mission is to enhance human health and public welfare by advancing the understanding of chemical mechanisms involved in disease processes, as well as the toxicity of drugs, environmental agents, and endogenous chemicals. Our objectives include fostering a diverse forum for sharing research in chemical toxicology, encouraging studies on chemical mechanisms of toxicity, and promoting collaborations among academia, industry, and policy makers in areas of shared scientific interest. We are also dedicated to supporting the leadership and professional development of scientists at all stages of their careers. Therefore, the requested funds will be allocated to support travel awards and expenses for graduate students, postdoctoral scholars, and junior faculty. The TOXI program will focus on the theme of "Toxicological Predictions, Markers, and Outcomes Affecting Human Health," complementing the National Meeting's overarching goals. The program includes three thematic symposia with invited oral presentations from both established and emerging researchers, offering a wide range of perspectives on each topic. These symposia are: (1) "Endogenous DNA Damage and Single Base Repair: Implications for Human Health and Disease," co-sponsored by the Division of Biological Chemistry, which will explore how environmental toxicants exacerbate endogenous DNA damage and repair; (2) "The Role of Investigative Toxicology in Drug-Induced Liver Toxicity," co-sponsored by the Division of Medicinal Chemistry, focusing on novel techniques like machine learning and AI to understand the mechanisms behind drug-induced liver injury; and (3) "Reactive Metabolite Post-translational Modifications and Their Analysis," co-sponsored by the Division of Analytical Chemistry, which will highlight analytical techniques for uncovering new modifications, isotope tracing, and systems-level studies of metabolism-driven post-translational modifications. We will also host three award symposia: a Young Investigator Award, which is chosen by the ACS journal Chemical Research in Toxicology, a Founders’ Award, which acknowledges the contributions of a founding member of the TOXI division, and a Keynote Address from a leader in the world of toxicology. We will also host two student and postdoctoral symposiums, with oral and poster presentations. The majority of presentations will explore the role of environmental exposures in disease and health, which aligns closely with the mission of the National Institute of Environmental Health Sciences (NIEHS). Project Number: 1R13ES038002-01 | Fiscal Year: 2025 | NIH Institute/Center: National Institute of Environmental Health Sciences (NIEHS) | Principal Investigator: Sarah Shuck | Institution: BECKMAN RESEARCH INSTITUTE/CITY OF HOPE, DUARTE, CA | Award Amount: $10,000 | Activity Code: R13 | Study Section: Special Emphasis Panel[ZES1 LWJ-S (R3)] View on NIH RePORTER: https://reporter.nih.gov/project-details/11247420