Funding Organization

National Institute of Dental and Craniofacial Research

318 opportunities

About

No description available for this funder.

Grants (318)

Mechanisms responsible for tooth morphogenesis in vertebrates

open
$367,206 - $367,206

Mechanistic Insights into Amelogenin Alternative Splicing and Its Multifunctional Regulatory Roles: Implications for Amelogenesis Imperfecta and Signaling Pathways

open
$693,185 - $693,185

The Role of nBMP2 in Macrophage Oral Immunomodulation

open
$310,500 - $310,500

Citrate regulation in amelogenesis

open
$311,000 - $311,000

Temporomandibular Joint Disc Replacement: Biomechanical Characterization and Novel Implant Assessment

open
$659,747 - $659,747

Structures and functions of natural products in periodontal disease

open
$453,797 - $453,797

Functional amyloid formation in streptococcus mutans

open
$574,966 - $574,966

Effects of Recurrent Periodontitis in HSC Function

open
$429,000 - $429,000

Mechanisms of age-related inflammatory dysregulation in the pathogenesis of periodontal disease

open
$311,687 - $311,687

Transposable element silencing as a regulator of salivary gland immune homeostasis

open
$449,625 - $449,625

Roles of neutrophil-sensory neuron interactions in dental pulp inflammation and pain

open
$249,000 - $249,000

An immunomodulatory approach to improve oral cavity wound healing

open
$933,580 - $933,580

Regulation of Palate Development and Innervation

open
$605,123 - $605,123

Ascertaining Multilevel drivers of hEad and Neck cancer Disparities (AMEND)

open
$516,769 - $516,769

National Dental Practice-Based Research Network: Coordinating Center

open
$299,992 - $299,992

Tools of a pioneer colonizer

open
$649,046 - $649,046

Targeted gene delivery to nociceptors

open
$80,352 - $80,352

Juberg-Marsidi Syndrome: Exploring Its Causes.

open
$444,438 - $444,438

Pro-CanDy (Probiotic-Loaded Hydrogels for the Prevention and Management of Oral Candidiasis and Dysbiosis)

open
$363,375 - $363,375

Exploring Streptococcus sanguinis Extracellular Vesicles as Regulators of Gingival Homeostasis and Periodontal Defense

open
$524,669 - $524,669

Genetic characterization of MesV sensory cells in normal development and in the neurodegenerative disease spinal muscular atrophy

open
$329,000 - $329,000

Functions of PRDM paralogs in craniofacial cartilage development

open
$305,000 - $305,000

Functional and structural characterization of phospholipase A2 in Porphyromonas gingivalis

open
$50,914 - $50,914

PREDICT: Advancing Periodontitis Care with Artificial Intelligence (AI)-Driven Diagnostics and Clinical Decision Support

open
$578,830 - $578,830

Intersection of Macrophage and Fibroblast Responses in Salivary Gland Fibrotic Injury

open
$35,571 - $35,571

MicroRNA-Mediated Mechanisms in Temporomandibular Joint Health and Disease

open
$706,281 - $706,281

Social stress induces bone loss and growth plate reduction

open
$393,750 - $393,750

Effects of Altered Immunity in XLH on Dental and Periodontal Infection

open
$116,937 - $116,937

3D human periodontal sulcus tissue model to study early fingerprints of oral dysbiosis

open
$50,338 - $50,338

Collaborative for REsearch to AdvanceTMD Evidence (CREATE)

open
$3,476,015 - $3,476,015

Advancing Craniosynostosis Treatment (ACT)Rare Diseases Consortium

open
$1,530,000 - $1,530,000

360° Collaborative Hub for AI in TMD Research (360° Chat-TMD)

open
$3,017,704 - $3,017,704

Angiogenic and Anti-microbial Supports for Pulp Regeneration

open
$582,724 - $582,724

Mechanisms for Impaired Diabetic Wound Healing

open
$521,495 - $521,495

Deciphering Cellular and Genetic Features that Give Rise to Osteonecrosis of the Jaw (ONJ R01)

open
$584,420 - $584,420

Pathogen Synergy and Immune Subversion in Periodontal Disease

open
$568,759 - $568,759

Oral Epithelial Cells, Candida and PMN Activation

open
$695,970 - $695,970

Unveiling Cryptic Connections in Streptococcus mutans: Hidden Protein Interaction Networks, Global Posttranscriptional Gene Regulation, and Therapeutic Potential

open
$634,041 - $634,041

Impact of Bariatric Surgery on the Risk of Adverse Oral Health Outcomes

open
$323,366 - $323,366

Identifying non-coding sources of mammalian craniofacial variation

open
$128,191 - $128,191

Role of immunomodulators IL-33 and SPRR in oropharyngeal candidiasis

open
$449,625 - $449,625

The role of taste receptor cells in periodontal homeostasis

open
$522,405 - $522,405

PDGFR dimer-specific dynamics in the craniofacial mesenchyme

open
$513,174 - $513,174

Project 1

open
$869,003 - $869,003

Advancing Craniosynostosis Treatment (ACT) Rare Diseases Consortium Administrative Core

open
$363,105 - $363,105

Elucidating The Immunoregulatory Role of Dendritic Cell Subsets in Periodontal Disease

open
$320,660 - $320,660

MASTL Kinase in DNA Repair and Treatment Resistance in Oral Squamous Cell Carcinoma

open
$42,358 - $42,358

Development of a Rhesus Macaque Model of Persistent Oral HPV and HIV Co-infection to Study Oropharyngeal Cancer Induction

open
$44,984 - $44,984

Cultivating Researchers in Oral and Systemic health Studies (CROSS)

open
$133,239 - $133,239

Defining the mechanisms of Epstein-Barr virus persistence and recurrence

open
$488,772 - $488,772

Novel Granular Hydrogels for Theranostic Management of Periodontitis

open
$121,667 - $121,667

Dentin Sialophosphoprotein (DSPP) Preprotein Signal Peptide Removal and Dentinogenesis Imperfecta (DGI)

open
$346,500 - $346,500

Medicaid coverage of treatment for periodontal disease and its impact on health outcomes

open
$185,918 - $185,918

Dental Research Intensive Program for Undergradate Students

open
$134,934 - $134,934

Developmental and molecular basis for a craniofacial metabolic syndrome

open
$190,576 - $190,576

lluminating the Role of the Novel G Protein-Coupled P2Y10 Receptor in Sjögren’s Disease Pathophysiology

open
$156,833 - $156,833

Neural Crest Regulation of Embryonic Calcium Uptake

open
$240,750 - $240,750

Mechanisms of hyperactive Ras signaling in craniofacial and dental diseases

open
$600,029 - $600,029

Defining TRPV4 contribution of Schwann cells to oral cancer pain

open
$162,743 - $162,743

The impact of bacterial oxidative stress responses on the ecology and pathogenicity of oral streptococci

open
$470,279 - $470,279

Nutritional Niches within Supragingival Biofilms

open
$163,561 - $163,561

Addition of a Reverse Amide to Methacrylate-Based Dental Materials to Inhibit Microbial Biofilm Formation.

open
$151,926 - $151,926

Mechanisms underlying spatial interaction in the oral microbiota

open
$137,609 - $137,609

Regulating Skeletal Stem Cell and Neutrophil Dynamics for Improved Cleft Palate Bone Regeneration by Newly Designed Surrogate Bone Morphogenetic Protein-2

open
$129,420 - $129,420

Genetic Regulatory Network in Craniofacial Development

open
$762,445 - $762,445

Validation of a clinically accessible prognostic biomarker for oropharynx cancer using molecular and spatial data

open
$129,226 - $129,226

SkillFlix for Dental Professionals: Video-based Microskills Training to Improve Dental Professionals' Response to Problem Behaviors of Pediatric Patients with IDD

open
$306,618 - $306,618

The Role of CD4+ Memory T cell Subtypes in Periodontal Disease Recurrence

open
$247,190 - $247,190

Multiparametric characterization of periodontal tissues for inflammation monitoring using quantitative ultrasound, texture analysis and machine learning

open
$80,148 - $80,148

Protein Phosphoribosylation: Characterization of a novel protein modification

open
$178,000 - $178,000

Leveraging single-cell co-culture and gene expression profiling to identify tumor antigen-specific T cells in oral cancer

open
$390,000 - $390,000

Systemic/Abscopal Anti-Tumor Immune Responses during IAP Antagonism and Radiation

open
$234,750 - $234,750

Identification of diffusible small molecules that regulate replication of Porphyromonas gingivalis

open
$201,250 - $201,250

Cellular plasticity in salivary gland regeneration

open
$454,108 - $454,108

Improving Caries Diagnosis with Targeted Nanoparticle-Enhanced AI-Assisted Intraoral Imaging

open
$294,632 - $294,632

Investigating the Regulatory Logic Underlying Meningeal Development and Tumorigenesis

open
$162,281 - $162,281

Phosphate and Enamel Formation

open
$677,989 - $677,989

Harvard MD Anderson Collaborative to Reduce LyMphatic MOrbidity in Head and Neck Cancer with Artificial Intelligence (HARMONiC-AI)

open
$716,638 - $716,638

Epigenetic Compounds Stimulating Dental Bone Repair

open
$306,868 - $306,868

Mertk-driven regeneration of alveolar bone

open
$476,287 - $476,287

Effects of the oral microbiome on Adverse Outcomes of Pediatric Hematopoietic Cell Transplantation

open
$205,000 - $205,000

The role of LSD1 in regulating periodontal induced bone loss

open
$198,006 - $198,006

Data science approaches to classify aggressive tissue phenotypes and predict disease-free survival in HPV-negative head and neck squamous cell carcinoma (HNSCC)

open
$168,610 - $168,610

AI-linked cytomics-on-a-chip to enable near-real time identification and management of oral lichenoid lesions in primary care

open
$1,178,476 - $1,178,476

Cellular and molecular control of periodontal tissue regeneration

open
$547,435 - $547,435

Sharpey's fibers and PDL regeneration

open
$579,200 - $579,200

Optoelectroactive citrate biocomposites for bone regeneration

open
$541,093 - $541,093

Effects of Preventive Dental Services and Requiring Dental Screening Certificates for School on Academic Achievement

open
$155,500 - $155,500

Functions of PRDM Histone Methyltransferases during Cartilage Development in the Craniofacial Skeleton

open
$222,211 - $222,211

CD38 signaling in aging-associated immune responses induced by oral pathogens

open
$226,500 - $226,500

Leveraging whole genome sequencing and functional genomic characterization to improve NSCLP gene discovery

open
$598,122 - $598,122

Clinically-calibrated Accelerated Fatigue Test for Predicting the Clinical Performance of Dental Restorative Materials

open
$441,247 - $441,247

Demystifying DMFT/DMFS: Pragmatic nationwide assessment of dental caries outcomes from NHANES

open
$219,132 - $219,132

Cellular senescence contributes to salivary gland dysfunction in Sjögren’s syndrome

open
$248,750 - $248,750

IL-17 receptor signaling in megakaryocytes and the implications for oral mucosal immune responses during oropharyngeal candidiasis

open
$473,632 - $473,632

Salmonella derived nanoparticles for cancer immunotherapy

open
$204,688 - $204,688

Temporo-masseteric Nerve Block in post-wisdom tooth extraction pain - a randomized study

open
$168,228 - $168,228

Immune-derived mediators of salivary gland development and differentiation

open
$628,965 - $628,965

Apical extracellular matrix during organ formation

open
$146,999 - $146,999

Epigenetic Therapy of Periimplantitis

open
$582,000 - $582,000

Polyamine blockade and anti-tumor immunity in head and neck squamous cell carcinoma

open
$170,208 - $170,208

Mechanisms of Macroglossia in Beckwith-Wiedemann Syndrome

open
$818,112 - $818,112

Evidence-based optimization of treatment timing in the craniofacial complex

open
$551,608 - $551,608

Mechanisms of Tissue Repair

open
$534,502 - $534,502

Targeting the stress-specific function of replication protein A in oral squamous cell carcinoma

open
$192,865 - $192,865

Deep Reasoning AI Virtual Anatomical Technology & Augmented Reasoning Platform: Application to Craniomaxillofacial Reconstruction

open
$350,000 - $350,000

Irx1 regulation of oral tissue repair and maintenance.

open
$480,840 - $480,840

Automated Characterization of Arterial Calcification in Dental Cone Beam Computed Tomography as Predictors of Cardiovascular Disease

open
$150,989 - $150,989

Kalirin and Osteocyte Dysfunction: Implications Across Skeletal Sites and Experimental Periodontitis

open
$55,338 - $55,338

Periodontal Regeneration with Supramolecular Nanomaterials

open
$456,500 - $456,500

ENPP1 Roles and ATP Metabolism in Cementogenesis

open
$155,500 - $155,500

Discovery of streptococcal natural products with activity against the endodontic pathogen Enterococcus faecalis

open
$310,000 - $310,000

Assessing marginal associations between dental caries and periodontal diseases and their determinants in cross-sectional studies

open
$319,624 - $319,624

Metabolic-Purinergic fitness in periodontal health and disease

open
$381,216 - $381,216

Mechanisms of Integrative and Conjugative Elements in Oral Bacteria

open
$374,511 - $374,511

Immune receptor degradation for immune evasion of head and neck cancer

open
$633,851 - $633,851

New advances to break the genetic tractability barrier of human Prevotella species

open
$234,000 - $234,000

Osteocytes-bacteria interaction via NOD1 as a mechanism of bone loss in periodontitis

open
$322,313 - $322,313

Therapeutic Targeting of Apical Periodontal T-Cells in Chronic Oral Inflammation

open
$180,943 - $180,943

Identifying transcriptional interplay between skin and oral ectoderm during mandibular patterning

open
$503,648 - $503,648

Developing SWIR fluorophores for enhanced visualization of buried nerves in head and neck cancer surgery

open
$620,592 - $620,592

A web-based clearinghouse for researchers and dental providers to increase participation in oral health research and clinical trials

open
$304,998 - $304,998

ARID1 proteins orchestrate cranial neural crest differentiation

open
$493,458 - $493,458

Enamel 11 International Conference

open
$15,000 - $15,000

Practitioners Approach to Oral Appliance Therapy for Obstructive Sleep Apnea and the Impact on Patients Outcomes

open
$449,861 - $449,861

Leveraging Microsurgery and Bioprinting for Rapidly Oriented Vascularized Tissue Engineering

open
$685,594 - $685,594

Development of an Integrated Dental Plaque Bioanalytical Platform for Point-of-Care Diagnostics of Oral Diseases

open
$422,665 - $422,665

SARS-CoV-2 tropism and immunomodulation in salivary gland

open
$401,500 - $401,500

Sex-specific immune microenvironment in oral cancer

open
$156,000 - $156,000

A Chairside Diagnostic to Reduce the Need for Endodontic Retreatment

open
$443,490 - $443,490

Single-Cell-Resolved Mapping and Evolution-Driven Functional Interrogation of Human Midface Enhancers

open
$804,478 - $804,478

Neural Circuit Mechanisms of Peripheral Nerve Stimulation for Trigeminal Neuropathic Pain

open
$239,405 - $239,405

Epigenetic Regulation of KSHV Latency

open
$583,289 - $583,289

Association of Denosumab Therapy with Tooth Root Resorption

open
$427,625 - $427,625

Integrating population-wide oral microbiome data to better understand health differences in the United States

open
$198,000 - $198,000

Evaluation and Implementation of Malnutrition Screening tools in dental settings

open
$165,724 - $165,724

Targeting Systems Vulnerabilities in the EGFR/HER3/HER2 Oncogenic Signaling Circuitry: New Precision Therapies for Oral Cancer

open
$483,360 - $483,360

Systematic identification of drivers controlling Fusobacterium and oral squamous cell carcinoma interactions

open
$442,750 - $442,750

Function of Zymogen Granule 16B (ZG16B) in Salivary Glands

open
$55,338 - $55,338

Defining the role of tissue-resident macrophages during salivary gland morphogenesis

open
$50,338 - $50,338

Exposome-on-a-chip: eliminating the elusiveness of the flavonoid hesperidin effect on bone and BMP function

open
$424,560 - $424,560

Development of a human salivary gland-on-a-chip composed of both parenchyma and stroma to model dry mouth caused by radiotherapy

open
$409,960 - $409,960

Harnessing immune-epithelial interactions to promote restoration of salivary gland function after IR

open
$644,970 - $644,970

Regeneration of radiation-damaged salivary glands using neurogenicstimulation of stem cells

open
$1,039,386 - $1,039,386

The role of primary cilia and C2cd3 in craniofacial skeletogenesis

open
$646,212 - $646,212

A multifaceted investigation of speech outcome after maxillary advancement

open
$161,644 - $161,644

Selective Recruitment of RSK Protein Kinases Through Non-Catalytic Docking Interactions

open
$461,375 - $461,375

Discovery of regulatory and cryptic splice-impacting variants in facial ectoderm-expressed genes: a secondary analysis of GMKF orofacial cleftdata.

open
$313,000 - $313,000

Engineering Oral Tumor Microcirculation: Blood and lymphatic capillary network-enabled Human Oral Tumor Microenvironment Chips for Preclinical Research

open
$421,625 - $421,625

Enhancing Dental and Craniomaxillofacial Surgery Outcomes with Cost-Effective and Scalable Animal-Free Amino Acid-Based Membranes for Guided Bone Regeneration

open
$976,000 - $976,000

An organ on-a-chip model of oral cancer and bone invasion

open
$704,206 - $704,206

Understanding viral mechanisms to inform oncolytic therapies for EBV-associated lymphomas in PLWH

open
$601,309 - $601,309

Human Pluripotent Stem Cells and Organoids for Salivary Gland Regeneration

open
$35,204 - $35,204

Dissecting motor cortex modulation of nociception during chronic pain

open
$248,999 - $248,999

Tackling Treg mediated resistance to radiation and anti-PDL1 in HNSCC's

open
$499,311 - $499,311

Novel OrganoPET Assay for Precision Therapy of Head and Neck Cancer

open
$249,000 - $249,000

Mechanisms of salivary epithelium-specific expansion post-irradiation

open
$714,711 - $714,711

Pathogenicity of ethanol tolerant strains of Candida albicans in the oral cavity

open
$463,530 - $463,530

Feasibility of a New Methodology for Dental Education in Temporomandibular Disorders through Virtual Patient-Based Learning

open
$105,450 - $105,450

Targeting PDE4 in Sjögren's Syndrome Xerostomia

open
$429,000 - $429,000

TRPM2-mediated immune activation initiates radiation-induced loss of oral function

open
$622,744 - $622,744

Mineral Scaffold-Modulated Senescence in Irradiated Bone

open
$520,093 - $520,093

An emergency department provider centered intervention for non-traumatic dental condition management

open
$248,997 - $248,997

Therapy Induced Senescence as a Potent Therapeutic Target

open
$45,290 - $45,290

Oral Cancer Diagnosis and Outcomes: Role of Medicaid Dental Coverage and Dental Utilization

open
$449,358 - $449,358

Developing novel 3D printed grafts for nasal reconstruction

open
$305,320 - $305,320

Distinct roles of neural crest cell populations in cranial suture development and disease

open
$315,000 - $315,000

Comparative Experimental Evolution of Gene Essentiality in Streptococcus sanguinis and S. mutans

open
$310,500 - $310,500

A Preliminary Elucidation of the Role of Dietary Fiber in Mitigating Sarcopenia Risk in Head and Neck Cancer

open
$286,000 - $286,000

UNDERSTANDING THE MECHANISMS BEHIND RADIOTHERAPY RESISTANCE OF IMMUNOLOGICALLY COLD HEAD AND NECK CANCER

open
$320,000 - $320,000

Six1 role on cell fate decisions within the mouse mandibular arch at single-cell resolution.

open
$315,289 - $315,289

Unraveling dentin and enamel roles on the development and progression of wedge-shaped noncarious cervical lesions

open
$311,000 - $311,000

Expression of markers of type 2 diabetes-induced premature cellular senescence in gingival biopsies of individuals with periodontal health and periodontitis

open
$307,000 - $307,000

Targeting of HPV oncoproteins using novel antibody therapeutics

open
$315,000 - $315,000

Identification of Rare Variants for Orofacial Clefts Using Publicly Available Datasets

open
$295,856 - $295,856

Deciphering the mechanism of response to novel HPV-specific viral immune therapy in HPV associated head and neck cancer

open
$451,000 - $451,000

Gene Regulation and Physiology of Oral Streptococci

open
$434,625 - $434,625

Mechanisms of cannabinoid-resistance among oral spirochetes

open
$431,750 - $431,750

Improving the design and implementation of school-based oral health programs using secondary data analysis

open
$322,000 - $322,000

ACTL6a ties metabolic reprogramming to cancer stem cell maintenance in oral cavity squamous cell carcinoma

open
$308,223 - $308,223

Development and Validation of an MRI-Compatible Jaw Metabolic Stressor Task

open
$299,782 - $299,782

Mechanistic investigation of multispecies interactions in clear aligner induced periodontal inflammation

open
$398,000 - $398,000

Gene Regulatory Mechanisms of Mll4 in Tooth Enamel Development

open
$320,200 - $320,200

Enhancing bacteriophage function with coevolution and synthetic biology

open
$198,046 - $198,046

Administrative Supplement for Probabilistic Deep Learning Cervical Lymph-Node Auto-Segmentation For Imaging-enhanced Evaluation of Extracapsular Extension Risk (PDL-CLASIFIER)

open
$175,256 - $175,256

Using Novel Machine Learning Approaches to Understand Subgingival Microbiome Heterogeneity in Relation to Health and Disease

open
$121,630 - $121,630

Optimizing Oral Cancer Screening and Precision Management of Potentially Malignant Oral Lesions

open
$465,582 - $465,582

The role of the Foxi3 transcription factor in craniofacial microsomia

open
$573,768 - $573,768

Control of Virulence Properties in the Major Human Oral Fungal Pathogen Candida albicans by the Asc1 Translational Regulator

open
$40,549 - $40,549

Characterizing the microbial and inflammatory state within distant clinically healthy tissues in patients with active periodontal disease

open
$311,000 - $311,000

Evaluating CT/Xray imaging-correlated impedance-based metrics for predictive surgical osseointegration and injury prevention

open
$220,000 - $220,000

Biomimetic Nitric Oxide and Hydroxyapatite Duo for Advanced Direct Pulp Capping

open
$408,375 - $408,375

Streptococcus species as potential therapeutics for oropharyngeal squamous cell carcinoma

open
$592,080 - $592,080

Peptide Discovery for Osteogenesis

open
$300,155 - $300,155

Determining molecular mechanisms of damage and repair in an oral mucosa chip

open
$306,200 - $306,200

Role of hyaluronan in YAP signaling on TMJ health and pathology

open
$507,006 - $507,006

Inhibition of Hedgehog Signaling as a Therapeutic Strategy for OSCC

open
$616,000 - $616,000

Ontology-based aPplications of mUlti-discipLinary knowlEdge on orodeNtal Conditions and outcomEs (OPULENCE)

open
$736,507 - $736,507

Development of an early tooth organoid via human induced pluripotent stem cells

open
$435,167 - $435,167

Engineering Mechanisms Causing Adverse Biofilm Responses to 3D Printed Titanium Surfaces

open
$377,030 - $377,030

Myogenic Mechanisms of Craniofacial Skeletal Muscle Regeneration

open
$169,992 - $169,992

In Toto Readout of Transcriptomes and Lineage Relationships in Native Craniofacial Tissues

open
$688,679 - $688,679

The Interplay of Mesenchymal Stem Cells and Neutrophils During Rapid Maxillary Expansion

open
$136,711 - $136,711

Investigation of New Molecules in Tooth and Root Developmental Anomalies

open
$297,000 - $297,000

Controlled delivery of mitochondria for craniofacial bone healing

open
$447,009 - $447,009

Microphysiological systems to recapitulate and interrogate Sjögren’s disease salivary gland pathogenesis

open
$432,209 - $432,209

KSHV Replication and Trained Immunity

open
$505,056 - $505,056

Mechanisms sustaining lytic herpesviral infection in the oral cavity

open
$466,640 - $466,640

Role of Macrophage Migration Inhibitory Factor (MIF) in KSHV-associated Malignancies

open
$306,000 - $306,000

Lysosome-targeting chimeras degrading immune checkpoint proteins to enhance immunoradiotherapy of head and neck cancer

open
$129,289 - $129,289

Leveraging Advances in Practices and Outcomes in Cleft Care: The LEAP Study

open
$1,281,274 - $1,281,274

From Crest to Bone: Understanding neural crest skeletogenic capacity along the neural axis

open
$162,281 - $162,281

Zinc nanocrystals from zinc tetraammine fluoride for caries arrest and remineralization

open
$297,711 - $297,711

Developing AI-Derived Multilevel Risk Scores for Oral Cavity and Oropharyngeal Cancer Patients

open
$325,176 - $325,176

Chemoprevention of Electronic Cigarette Promoted Oral Squamous Cell Carcinoma

open
$317,000 - $317,000

Molecular Mechanism by which Notch Signaling regulates TMJ Osteoarthritis

open
$419,379 - $419,379

Point of Care Detection of HPV and P16 in Saliva

open
$1,414,853 - $1,414,853

Development and characterization of metastatic Myb-NFIB fusion adenoid cystic carcinoma cell line models

open
$451,000 - $451,000

A Novel Anti-infective Therapy for Treating Periodontitis

open
$309,038 - $309,038

Validating the hybrid epithelial/mesenchymal state as a biomarker of treatment response and outcomes in head and neck cancer

open
$702,871 - $702,871

Identifying cellular and molecular signatures from distinct T cell receptor clonotypes associated with favorable immune checkpoint inhibitor responses in HNSCCs

open
$750,429 - $750,429

Modeling Hemifacial Spasm in Mice

open
$433,657 - $433,657

Silver Diamine Fluoride (SDF) and Medicaid Policy: Improving Pediatric Oral Health

open
$693,179 - $693,179

Exploiting immunostimulatory microbial pattern recognition to improve head and neck cancer therapy

open
$427,208 - $427,208

Commercialization Readiness Pilot for A Comprehensive Platform for Pediatric Cranial Evaluation

open
$1,000,000 - $1,000,000

Decoding Neuroimmune Interactions to Enhance Craniofacial Bone Healing

open
$521,362 - $521,362

Therapeutic mechanisms of iPSC-MSC derived extracellular vesicles on dry mouth caused by Sjorgren's syndrome or radiotherapy

open
$643,574 - $643,574

Bacteriophages in dental caries: Roles and potential as a therapy

open
$645,988 - $645,988

Effectiveness of an Early Intensive Preventive Dental Program by Oncology Providers to Reduce Dental Disease and Improve Compliance in Head and Neck Cancer Patients: OraRad IPDP

open
$681,331 - $681,331

Advancing the Genomics Knowledge Base for Oral Diseases

open
$673,091 - $673,091

The intersection of AI, clinical practice and health outcomes with linked Medical-Dental electronic records.

open
$438,768 - $438,768

Pre-vascularization of an Integrated 3D Human Osteo-Mucosal Model

open
$583,826 - $583,826

The Oral Microbiome and Cognitive Function

open
$332,787 - $332,787

Epstein-Barr virus nuclear antigen 2 in transcription regulation

open
$450,462 - $450,462

A Novel Immunological-Directed Probiotic for the Treatment of Sjögren’s Syndrome

open
$429,158 - $429,158

Oral Health Influences Among Emerging Adult Women of Central and South American ancestry

open
$235,954 - $235,954

A Pathomimetic Gingiva-on-a-Chip for Assessing Microbiota-Directed Anti-Inflammatory Therapeutics

open
$442,750 - $442,750

Investigating the role of ELAVL1 as a post-transcriptional regulator of cranial neural crest development

open
$50,006 - $50,006

Underscoring human oral host-pathogen interactions and modulation in an immunocompetent in vitro model of early dysbiosis

open
$540,629 - $540,629

Intraoperative stereo imaging for oral specimen orientation and margin visualization

open
$452,967 - $452,967

A Team Science Approach to the Co Development of Oral Mucosa for Therapeutic Purposes

open
$1,240,877 - $1,240,877

Frequent Standardized Oral Care Using Human Milk to Reduce Gastrointestinal Dysbiosis and Inflammation to Improve Health Outcomes and Reduce Cost in Preterm Very Low Birth Weight Infants

open
$511,706 - $511,706

Advancing Craniosynostosis Treatment (ACT) Rare Diseases Consortium Career Enhancement Core

open
$133,466 - $133,466

Establishing a novel 13C-labeled metabolite library for the study of dental caries

open
$597,807 - $597,807

Targeting TRPC1: A Novel Approach to Treat Oral Cancer

open
$315,000 - $315,000

Use of Apatinib-nanosponge conjugate to reduce post-radiation induced oral cavity and salivary fibrosis.

open
$298,942 - $298,942

Targeting CISD1-mediated ferropoptosis in head and neck cancer

open
$418,000 - $418,000

Small Molecule Inhibitors Against HPV-Induced Orophageal Cancers

open
$433,125 - $433,125

Dissecting CCL5 contribution to antigen specific T cell responses in head and neck cancers

open
$3,742,682 - $3,742,682

Fibronectin Modulation of Oral Cancer Nociception

open
$672,660 - $672,660

Bitter taste receptors in oral cancer tumor-associated macrophages

open
$511,578 - $511,578

Low-Burden High Fidelity Obstructive Sleep Apnea Screening Using Oral Cavity Images

open
$305,746 - $305,746

Senescent periodontal ligament cells as a potential therapeutic target for age-associated periodontitis

open
$385,116 - $385,116

Investigating the role of ESRP2 in craniofacial development using the cleft primary palate (cpp) avian model.

open
$50,324 - $50,324

Tissue-immunoengineering of TMJ neodisc implants

open
$589,135 - $589,135

AntiXero: An extended duration solution for cancer-associated dry mouth.

open
$406,496 - $406,496

Determining the role of Raftlin-2 in neural crest cell specification and migration

open
$50,338 - $50,338

Targeting Succinate Signaling for Innovative Pain Relief in Oral Cancer.

open
$3,892,146 - $3,892,146

Restoration of non-cavitated carious lesions in enamel using nano-fluorapatite particles

open
$270,594 - $270,594

Engineering Cell Fate in Salivary Gland Development

open
$249,000 - $249,000

Piezo1- Mediated Type H Vessel Formation in Periodontitis

open
$101,356 - $101,356

Gene regulatory programs underlying differences in neural crest developmental potential in the head and neck

open
$50,338 - $50,338

SCH: Multidimensional Microfluidic Salivary Sensor with Adversarial Knowledge Distillation for Point-of-Care Assessment of Periodontitis and Comorbidities

open
$287,077 - $287,077

Multimodal Multi-Electrode Array (MEA) for Probing Tooth Root Organoid Maturation and Sensory Innervation

open
$50,338 - $50,338

Caregiver-implemented early speech and language intervention for toddlers with cleft palate

open
$336,748 - $336,748

Nanodroplet Infused Analgesic-Wafer for Transmucosal Opioid-free Treatment of Subacute Oral Pain

open
$413,298 - $413,298

Redefining Dental Imaging: Low-Cost MRI with Relaxed Field Requirements

open
$341,970 - $341,970

Ultrasensitive detection of circulating DNA methylation for head and neck cancer prognosis

open
$712,674 - $712,674

Bioinformatics/data science Core (BDSC)

open
$869,004 - $869,004

Identifying Subgroups of Adolescents with Chronic Temporomandibular Disorder Pain to Guide Personalized Treatment

open
$310,295 - $310,295

Defining TMJ cartilage progenitors and their regulatory niche for TMJ regeneration

open
$655,455 - $655,455

Structural-functional studies of gingipain biogenesis and localization

open
$358,823 - $358,823

Targeting GTP Cyclohydrolase 1 for treating chronic orofacial pain

open
$392,312 - $392,312

Dichotomy of Phosphate Actions in Periodontal Health

open
$454,002 - $454,002

Medicaid Accountable Care Organizations and Children's Oral Health and Access to Care

open
$728,647 - $728,647

miR6891-5p-regulated X skewing in Sjögren's Disease: molecular mechanism, reversal strategies, and clinical significance

open
$363,221 - $363,221

Aging, Sex Bias, and CD8 T Cell Exhaustion in Salivary Gland Inflammation

open
$468,875 - $468,875

360 Whole-Person/Healthcare/Community TMD Research

open
$754,425 - $754,425

Deciphering transcription factor spatiotemporal and dosage effects in face development

open
$78,840 - $78,840

Investigating the molecular etiology of Keratinocyte Differentiation Factor 1 (KDF1) in disease phenotypes of the ectoderm.

open
$50,338 - $50,338

Integrative Predictors of Temporomandibular Degenerative Joint Disease

open
$698,865 - $698,865

Role of BAP1 in the biphasic life cycle of KSHV

open
$45,037 - $45,037

Harnessing Knowledge from the Social and Behavioral Sciences to Develop Sociobehavioral Interventions that Address Children's Oral Health Disparities

open
$18,000 - $18,000

Disease Etiology and Structural Proteomics of Jbts17

open
$41,058 - $41,058

Elucidating the effects of sublingual tablets containing buprenorphine on dental caries, and development of a novel formulation.

open
$47,454 - $47,454

Voice-activated antibacterial piezoelectric composites for dental restorations

open
$435,875 - $435,875

Determining the Impact of Metabolic Syndrome on the Oral Microbiome and Periodontal Health Using a Longitudinal Systems Biology Approach

open
$699,184 - $699,184

Investigating the roles of extracellular pyruvate in regulating Streptococcus mutans physiology and stress resistance

open
$419,375 - $419,375

Cartilage and bone of the lower jaw in development and disease

open
$760,727 - $760,727

Pharmacological inhibition of ENPP1 to promote cementum regeneration and periodontal return to function

open
$469,207 - $469,207

Probing the role of Selenomonas sputigena in supragingival biofilm spatial structuring and virulence

open
$249,000 - $249,000

The Development of an early detection tool for oral-dental radiation induced injury

open
$38,901 - $38,901

Transcriptional regulatory Mechanisms of Salivary gland Regeneration in a defined genetic model

open
$440,275 - $440,275

An Atlas of Bacterial Physiology in the Human Oral Cavity

open
$340,149 - $340,149

Radiation-guided theranostic agents to monitor response to oral cancer treatment

open
$427,625 - $427,625

PDGFRbeta-mediated skeletal-vascular crosstalk in calvarial bone marrow development

open
$341,000 - $341,000

Photochemical Tissue Passivation (PTP) to Reduce Temporomandibular Joint (TMJ) Osteoarthritis (OA)

open
$408,951 - $408,951

Treatment for Peri-implantitis via Local Immunomodulation and Effect on the Microbiome

open
$679,631 - $679,631

Role of tissue homeostasis in Sjogren's disease

open
$527,732 - $527,732

Investigation of Key Nicotinamide Adenine Dinucleotide Metabolism Pathway Roles in Support of Epstein-Barr Virus Replication

open
$135,000 - $135,000

Engineered Synthetic Low-Density Lipoprotein Nanoparticles for Enhanced Cancer Immunotherapy in Head and Neck Cancer

open
$644,452 - $644,452

Uncovering interactions between bioderived nanomaterials and water in novel dental adhesives: strategies for reduced moisture sensitivity

open
$298,613 - $298,613

The Role of MK2 on head and neck cancer cell migration, invasion, and metastases

open
$693,365 - $693,365

Developmental Systems Genomics of morphogenetic timing and facial shape variation

open
$795,730 - $795,730

Elucidating the etiology for Schneckenbecken dysplasia, a rare disease, using a vetrebrate model system

open
$154,000 - $154,000

Pathogenesis, Phenotypic Variation, and Prevention of Craniofacial Anomalies

open
$371,250 - $371,250

Revealing the Trajectory and Critical Roles of Retinoic Acid in Ameloblast Differentiation

open
$312,000 - $312,000

Regulation of early mandibular morphogenesis by the homeobox protein MSX1

open
$449,886 - $449,886

Elucidating subclonal evolution and fitness dynamics in oral carcinogenesis

open
$735,436 - $735,436

Workflow Optimization for School-based Preventive Oral Health Services Delivery

open
$555,081 - $555,081

2026 Craniofacial Morphogenesis and Tissue Regeneration Gordon Research Conference and Gordon Research Seminar

open
$23,000 - $23,000

Function-based annotation and classification of uncharacterized eukaryotic viruses in the human virome

open
$582,838 - $582,838

Hiding in plain sight: integrating AI with targeted bench methods to discover and characterize viruses in the human body

open
$423,366 - $423,366

Leveraging primary cell and organoid culture to identify and map the human virome

open
$587,718 - $587,718

Computational methods for benchmarking and development of best practices for virus discovery and characterization in the HVP consortium

open
$563,429 - $563,429

Developing computational, experimental and ecological approaches to study integrated phages and their hosts

open
$539,000 - $539,000

Unraveling the Regulation of Transcription and Activity of Calcium Transporter SLC24A4 in Enamel Formation

open
$451,000 - $451,000

Investigating the Role of Histamine and HRH1 in Mucus Secretion in the Salivary Glands

open
$75,852 - $75,852

Funder Overview

Total Opportunities318
Grants318
Contracts0

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