Funding Organization
National Institute of Dental and Craniofacial Research
306 opportunities
About
No description available for this funder.
Grants (306)
Functional and structural characterization of phospholipase A2 in Porphyromonas gingivalis
openMay 9, 2028$50,914 - $50,914
PREDICT: Advancing Periodontitis Care with Artificial Intelligence (AI)-Driven Diagnostics and Clinical Decision Support
openFeb 28, 2031$578,830 - $578,830
Intersection of Macrophage and Fibroblast Responses in Salivary Gland Fibrotic Injury
openMar 23, 2029$35,571 - $35,571
MicroRNA-Mediated Mechanisms in Temporomandibular Joint Health and Disease
openApr 30, 2031$706,281 - $706,281
Social stress induces bone loss and growth plate reduction
openMay 14, 2027$393,750 - $393,750
3D human periodontal sulcus tissue model to study early fingerprints of oral dysbiosis
openApr 14, 2027$50,338 - $50,338
Effects of Altered Immunity in XLH on Dental and Periodontal Infection
openMay 14, 2028$116,937 - $116,937
Collaborative for REsearch to AdvanceTMD Evidence (CREATE)
openJun 30, 2030$3,476,015 - $3,476,015
Advancing Craniosynostosis Treatment (ACT)Rare Diseases Consortium
openMay 31, 2030$1,530,000 - $1,530,000
360° Collaborative Hub for AI in TMD Research (360° Chat-TMD)
openJun 30, 2030$3,017,704 - $3,017,704
Angiogenic and Anti-microbial Supports for Pulp Regeneration
openJan 31, 2027$582,724 - $582,724
Mechanisms for Impaired Diabetic Wound Healing
openApr 30, 2031$521,495 - $521,495
Deciphering Cellular and Genetic Features that Give Rise to Osteonecrosis of the Jaw (ONJ R01)
openApr 30, 2030$584,420 - $584,420
Pathogen Synergy and Immune Subversion in Periodontal Disease
openApr 30, 2031$568,759 - $568,759
Oral Epithelial Cells, Candida and PMN Activation
openFeb 28, 2031$695,970 - $695,970
Unveiling Cryptic Connections in Streptococcus mutans: Hidden Protein Interaction Networks, Global Posttranscriptional Gene Regulation, and Therapeutic Potential
openApr 30, 2031$634,041 - $634,041
Impact of Bariatric Surgery on the Risk of Adverse Oral Health Outcomes
openApr 30, 2028$323,366 - $323,366
Identifying non-coding sources of mammalian craniofacial variation
openApr 30, 2028$128,191 - $128,191
The role of taste receptor cells in periodontal homeostasis
openApr 30, 2031$522,405 - $522,405
Role of immunomodulators IL-33 and SPRR in oropharyngeal candidiasis
openApr 30, 2028$449,625 - $449,625
PDGFR dimer-specific dynamics in the craniofacial mesenchyme
openApr 30, 2031$513,174 - $513,174
Project 1
openJun 30, 2030$869,003 - $869,003
Advancing Craniosynostosis Treatment (ACT) Rare Diseases Consortium Administrative Core
openMay 31, 2030$363,105 - $363,105
Elucidating The Immunoregulatory Role of Dendritic Cell Subsets in Periodontal Disease
openApr 5, 2028$320,660 - $320,660
MASTL Kinase in DNA Repair and Treatment Resistance in Oral Squamous Cell Carcinoma
openApr 7, 2028$42,358 - $42,358
Development of a Rhesus Macaque Model of Persistent Oral HPV and HIV Co-infection to Study Oropharyngeal Cancer Induction
openApr 14, 2027$44,984 - $44,984
Cultivating Researchers in Oral and Systemic health Studies (CROSS)
openMar 31, 2031$133,239 - $133,239
Defining the mechanisms of Epstein-Barr virus persistence and recurrence
openMar 31, 2031$488,772 - $488,772
Novel Granular Hydrogels for Theranostic Management of Periodontitis
openMar 31, 2028$121,667 - $121,667
Dentin Sialophosphoprotein (DSPP) Preprotein Signal Peptide Removal and Dentinogenesis Imperfecta (DGI)
openMar 31, 2031$346,500 - $346,500
Medicaid coverage of treatment for periodontal disease and its impact on health outcomes
openJan 31, 2027$185,918 - $185,918
Dental Research Intensive Program for Undergradate Students
openJan 31, 2030$134,934 - $134,934
Developmental and molecular basis for a craniofacial metabolic syndrome
openJan 31, 2027$190,576 - $190,576
lluminating the Role of the Novel G Protein-Coupled P2Y10 Receptor in Sjögren’s Disease Pathophysiology
openFeb 28, 2027$156,833 - $156,833
Mechanisms of hyperactive Ras signaling in craniofacial and dental diseases
openFeb 28, 2030$600,029 - $600,029
Addition of a Reverse Amide to Methacrylate-Based Dental Materials to Inhibit Microbial Biofilm Formation.
openFeb 28, 2027$151,926 - $151,926
Defining TRPV4 contribution of Schwann cells to oral cancer pain
openFeb 28, 2030$162,743 - $162,743
The impact of bacterial oxidative stress responses on the ecology and pathogenicity of oral streptococci
openFeb 28, 2030$470,279 - $470,279
Nutritional Niches within Supragingival Biofilms
openFeb 28, 2027$163,561 - $163,561
C. albicans interactions with S. mutans modulate cariogenic biofilm formation and virulence
openFeb 28, 2030$445,260 - $445,260
Mechanisms underlying spatial interaction in the oral microbiota
openJun 30, 2026$137,609 - $137,609
Regulating Skeletal Stem Cell and Neutrophil Dynamics for Improved Cleft Palate Bone Regeneration by Newly Designed Surrogate Bone Morphogenetic Protein-2
openFeb 28, 2027$129,420 - $129,420
Validation of a clinically accessible prognostic biomarker for oropharynx cancer using molecular and spatial data
openDec 31, 2029$129,226 - $129,226
Genetic Regulatory Network in Craniofacial Development
openJan 31, 2030$762,445 - $762,445
SkillFlix for Dental Professionals: Video-based Microskills Training to Improve Dental Professionals' Response to Problem Behaviors of Pediatric Patients with IDD
openOct 16, 2026$306,618 - $306,618
The Role of CD4+ Memory T cell Subtypes in Periodontal Disease Recurrence
openMar 31, 2030$247,190 - $247,190
Multiparametric characterization of periodontal tissues for inflammation monitoring using quantitative ultrasound, texture analysis and machine learning
openMar 31, 2027$80,148 - $80,148
Protein Phosphoribosylation: Characterization of a novel protein modification
openMar 31, 2027$178,000 - $178,000
Leveraging single-cell co-culture and gene expression profiling to identify tumor antigen-specific T cells in oral cancer
openMar 31, 2030$390,000 - $390,000
Systemic/Abscopal Anti-Tumor Immune Responses during IAP Antagonism and Radiation
openMar 31, 2027$234,750 - $234,750
Identification of diffusible small molecules that regulate replication of Porphyromonas gingivalis
openMar 31, 2027$201,250 - $201,250
Characterization of a conserved streptococcal membrane protein affecting manganese utilization
openMar 31, 2027$273,009 - $273,009
Cellular plasticity in salivary gland regeneration
openFeb 28, 2027$454,108 - $454,108
Investigating the Regulatory Logic Underlying Meningeal Development and Tumorigenesis
openMar 31, 2027$162,281 - $162,281
Improving Caries Diagnosis with Targeted Nanoparticle-Enhanced AI-Assisted Intraoral Imaging
openApr 2, 2027$294,632 - $294,632
Harvard MD Anderson Collaborative to Reduce LyMphatic MOrbidity in Head and Neck Cancer with Artificial Intelligence (HARMONiC-AI)
openJan 31, 2030$716,638 - $716,638
Phosphate and Enamel Formation
openJan 31, 2030$677,989 - $677,989
Epigenetic Compounds Stimulating Dental Bone Repair
openApr 7, 2027$306,868 - $306,868
Mertk-driven regeneration of alveolar bone
openMar 31, 2030$476,287 - $476,287
Effects of the oral microbiome on Adverse Outcomes of Pediatric Hematopoietic Cell Transplantation
openMar 31, 2027$205,000 - $205,000
The role of LSD1 in regulating periodontal induced bone loss
openMar 31, 2027$198,006 - $198,006
Data science approaches to classify aggressive tissue phenotypes and predict disease-free survival in HPV-negative head and neck squamous cell carcinoma (HNSCC)
openMar 31, 2028$168,610 - $168,610
AI-linked cytomics-on-a-chip to enable near-real time identification and management of oral lichenoid lesions in primary care
openMar 31, 2027$1,178,476 - $1,178,476
Cellular and molecular control of periodontal tissue regeneration
openMar 31, 2030$547,435 - $547,435
Optoelectroactive citrate biocomposites for bone regeneration
openMar 31, 2029$541,093 - $541,093
Sharpey's fibers and PDL regeneration
openMar 31, 2030$579,200 - $579,200
Effects of Preventive Dental Services and Requiring Dental Screening Certificates for School on Academic Achievement
openApr 30, 2027$155,500 - $155,500
CD38 signaling in aging-associated immune responses induced by oral pathogens
openApr 30, 2027$226,500 - $226,500
Functions of PRDM Histone Methyltransferases during Cartilage Development in the Craniofacial Skeleton
openApr 30, 2028$222,211 - $222,211
Clinically-calibrated Accelerated Fatigue Test for Predicting the Clinical Performance of Dental Restorative Materials
openApr 30, 2028$441,247 - $441,247
Leveraging whole genome sequencing and functional genomic characterization to improve NSCLP gene discovery
openFeb 28, 2030$598,122 - $598,122
Demystifying DMFT/DMFS: Pragmatic nationwide assessment of dental caries outcomes from NHANES
openApr 30, 2027$219,132 - $219,132
Cellular senescence contributes to salivary gland dysfunction in Sjögren’s syndrome
openApr 30, 2027$248,750 - $248,750
IL-17 receptor signaling in megakaryocytes and the implications for oral mucosal immune responses during oropharyngeal candidiasis
openApr 30, 2028$473,632 - $473,632
Salmonella derived nanoparticles for cancer immunotherapy
openApr 30, 2027$204,688 - $204,688
Epigenetic Therapy of Periimplantitis
openJan 31, 2030$582,000 - $582,000
Immune-derived mediators of salivary gland development and differentiation
openApr 30, 2030$628,965 - $628,965
Apical extracellular matrix during organ formation
openApr 30, 2027$146,999 - $146,999
Temporo-masseteric Nerve Block in post-wisdom tooth extraction pain - a randomized study
openApr 30, 2029$168,228 - $168,228
Polyamine blockade and anti-tumor immunity in head and neck squamous cell carcinoma
openApr 30, 2029$170,208 - $170,208
Mechanisms of Macroglossia in Beckwith-Wiedemann Syndrome
openJan 31, 2030$818,112 - $818,112
Evidence-based optimization of treatment timing in the craniofacial complex
openJan 31, 2030$551,608 - $551,608
Targeting the stress-specific function of replication protein A in oral squamous cell carcinoma
openApr 30, 2027$192,865 - $192,865
Deep Reasoning AI Virtual Anatomical Technology & Augmented Reasoning Platform: Application to Craniomaxillofacial Reconstruction
openMay 7, 2027$350,000 - $350,000
Irx1 regulation of oral tissue repair and maintenance.
openMay 7, 2027$480,840 - $480,840
Automated Characterization of Arterial Calcification in Dental Cone Beam Computed Tomography as Predictors of Cardiovascular Disease
openMay 31, 2027$150,989 - $150,989
Kalirin and Osteocyte Dysfunction: Implications Across Skeletal Sites and Experimental Periodontitis
openMay 31, 2027$55,338 - $55,338
Periodontal Regeneration with Supramolecular Nanomaterials
openMay 31, 2027$456,500 - $456,500
ENPP1 Roles and ATP Metabolism in Cementogenesis
openMay 31, 2027$155,500 - $155,500
Discovery of streptococcal natural products with activity against the endodontic pathogen Enterococcus faecalis
openMay 31, 2027$310,000 - $310,000
Assessing marginal associations between dental caries and periodontal diseases and their determinants in cross-sectional studies
openMay 31, 2027$319,624 - $319,624
Metabolic-Purinergic fitness in periodontal health and disease
openMar 31, 2030$381,216 - $381,216
Mechanisms of Integrative and Conjugative Elements in Oral Bacteria
openMay 31, 2028$374,511 - $374,511
Immune receptor degradation for immune evasion of head and neck cancer
openMar 31, 2030$633,851 - $633,851
New advances to break the genetic tractability barrier of human Prevotella species
openMay 31, 2027$234,000 - $234,000
Osteocytes-bacteria interaction via NOD1 as a mechanism of bone loss in periodontitis
openJun 14, 2027$322,313 - $322,313
Identifying transcriptional interplay between skin and oral ectoderm during mandibular patterning
openMar 31, 2030$503,648 - $503,648
A web-based clearinghouse for researchers and dental providers to increase participation in oral health research and clinical trials
openJun 12, 2027$304,998 - $304,998
Developing SWIR fluorophores for enhanced visualization of buried nerves in head and neck cancer surgery
openJun 12, 2027$620,592 - $620,592
Therapeutic Targeting of Apical Periodontal T-Cells in Chronic Oral Inflammation
openMay 31, 2030$180,943 - $180,943
ARID1 proteins orchestrate cranial neural crest differentiation
openMar 31, 2030$493,458 - $493,458
Leveraging Microsurgery and Bioprinting for Rapidly Oriented Vascularized Tissue Engineering
openMay 31, 2030$685,594 - $685,594
Enamel 11 International Conference
openJun 15, 2026$15,000 - $15,000
Practitioners Approach to Oral Appliance Therapy for Obstructive Sleep Apnea and the Impact on Patients Outcomes
openJun 16, 2027$449,861 - $449,861
Development of an Integrated Dental Plaque Bioanalytical Platform for Point-of-Care Diagnostics of Oral Diseases
openJun 16, 2027$422,665 - $422,665
SARS-CoV-2 tropism and immunomodulation in salivary gland
openJun 16, 2027$401,500 - $401,500
Neural Circuit Mechanisms of Peripheral Nerve Stimulation for Trigeminal Neuropathic Pain
openJun 30, 2027$239,405 - $239,405
Sex-specific immune microenvironment in oral cancer
openJun 30, 2027$156,000 - $156,000
Association of Denosumab Therapy with Tooth Root Resorption
openJun 30, 2027$427,625 - $427,625
Integrating population-wide oral microbiome data to better understand health differences in the United States
openJun 30, 2027$198,000 - $198,000
Single-Cell-Resolved Mapping and Evolution-Driven Functional Interrogation of Human Midface Enhancers
openMar 31, 2030$804,478 - $804,478
Epigenetic Regulation of KSHV Latency
openMar 31, 2030$583,289 - $583,289
A Chairside Diagnostic to Reduce the Need for Endodontic Retreatment
openJun 30, 2027$443,490 - $443,490
Function of Zymogen Granule 16B (ZG16B) in Salivary Glands
openJun 30, 2027$55,338 - $55,338
Systematic identification of drivers controlling Fusobacterium and oral squamous cell carcinoma interactions
openJun 30, 2027$442,750 - $442,750
Targeting Systems Vulnerabilities in the EGFR/HER3/HER2 Oncogenic Signaling Circuitry: New Precision Therapies for Oral Cancer
openJun 30, 2030$483,360 - $483,360
Evaluation and Implementation of Malnutrition Screening tools in dental settings
openJun 30, 2029$165,724 - $165,724
Defining the role of tissue-resident macrophages during salivary gland morphogenesis
openJun 30, 2028$50,338 - $50,338
The role of primary cilia and C2cd3 in craniofacial skeletogenesis
openApr 30, 2030$646,212 - $646,212
A multifaceted investigation of speech outcome after maxillary advancement
openJun 30, 2030$161,644 - $161,644
Harnessing immune-epithelial interactions to promote restoration of salivary gland function after IR
openJun 30, 2030$644,970 - $644,970
Development of a human salivary gland-on-a-chip composed of both parenchyma and stroma to model dry mouth caused by radiotherapy
openJun 30, 2027$409,960 - $409,960
Regeneration of radiation-damaged salivary glands using neurogenicstimulation of stem cells
openJun 30, 2027$1,039,386 - $1,039,386
Exposome-on-a-chip: eliminating the elusiveness of the flavonoid hesperidin effect on bone and BMP function
openJun 30, 2027$424,560 - $424,560
Engineering Oral Tumor Microcirculation: Blood and lymphatic capillary network-enabled Human Oral Tumor Microenvironment Chips for Preclinical Research
openJun 30, 2027$421,625 - $421,625
Discovery of regulatory and cryptic splice-impacting variants in facial ectoderm-expressed genes: a secondary analysis of GMKF orofacial cleftdata.
openJun 30, 2027$313,000 - $313,000
Selective Recruitment of RSK Protein Kinases Through Non-Catalytic Docking Interactions
openJun 30, 2027$461,375 - $461,375
Enhancing Dental and Craniomaxillofacial Surgery Outcomes with Cost-Effective and Scalable Animal-Free Amino Acid-Based Membranes for Guided Bone Regeneration
openJun 30, 2027$976,000 - $976,000
An organ on-a-chip model of oral cancer and bone invasion
openMar 31, 2030$704,206 - $704,206
Understanding viral mechanisms to inform oncolytic therapies for EBV-associated lymphomas in PLWH
openMar 31, 2030$601,309 - $601,309
Human Pluripotent Stem Cells and Organoids for Salivary Gland Regeneration
openJun 30, 2028$35,204 - $35,204
Dissecting motor cortex modulation of nociception during chronic pain
openJun 30, 2028$248,999 - $248,999
Tackling Treg mediated resistance to radiation and anti-PDL1 in HNSCC's
openJun 30, 2029$499,311 - $499,311
Novel OrganoPET Assay for Precision Therapy of Head and Neck Cancer
openJun 30, 2028$249,000 - $249,000
Targeting PDE4 in Sjögren's Syndrome Xerostomia
openJun 30, 2027$429,000 - $429,000
Feasibility of a New Methodology for Dental Education in Temporomandibular Disorders through Virtual Patient-Based Learning
openJun 30, 2027$105,450 - $105,450
Mechanisms of salivary epithelium-specific expansion post-irradiation
openMar 31, 2030$714,711 - $714,711
Pathogenicity of ethanol tolerant strains of Candida albicans in the oral cavity
openJun 30, 2027$463,530 - $463,530
Mineral Scaffold-Modulated Senescence in Irradiated Bone
openMar 31, 2030$520,093 - $520,093
TRPM2-mediated immune activation initiates radiation-induced loss of oral function
openMar 31, 2030$622,744 - $622,744
An emergency department provider centered intervention for non-traumatic dental condition management
openJun 30, 2028$248,997 - $248,997
Therapy Induced Senescence as a Potent Therapeutic Target
openJun 30, 2027$45,290 - $45,290
Oral Cancer Diagnosis and Outcomes: Role of Medicaid Dental Coverage and Dental Utilization
openMar 31, 2030$449,358 - $449,358
Developing novel 3D printed grafts for nasal reconstruction
openJun 30, 2026$305,320 - $305,320
Distinct roles of neural crest cell populations in cranial suture development and disease
openJul 14, 2027$315,000 - $315,000
UNDERSTANDING THE MECHANISMS BEHIND RADIOTHERAPY RESISTANCE OF IMMUNOLOGICALLY COLD HEAD AND NECK CANCER
openJul 14, 2027$320,000 - $320,000
Comparative Experimental Evolution of Gene Essentiality in Streptococcus sanguinis and S. mutans
openJul 14, 2027$310,500 - $310,500
A Preliminary Elucidation of the Role of Dietary Fiber in Mitigating Sarcopenia Risk in Head and Neck Cancer
openJul 14, 2027$286,000 - $286,000
Six1 role on cell fate decisions within the mouse mandibular arch at single-cell resolution.
openJul 14, 2027$315,289 - $315,289
Expression of markers of type 2 diabetes-induced premature cellular senescence in gingival biopsies of individuals with periodontal health and periodontitis
openJul 14, 2027$307,000 - $307,000
Unraveling dentin and enamel roles on the development and progression of wedge-shaped noncarious cervical lesions
openJul 14, 2027$311,000 - $311,000
Deciphering the mechanism of response to novel HPV-specific viral immune therapy in HPV associated head and neck cancer
openJul 14, 2027$451,000 - $451,000
Identification of Rare Variants for Orofacial Clefts Using Publicly Available Datasets
openJul 14, 2027$295,856 - $295,856
Targeting of HPV oncoproteins using novel antibody therapeutics
openJul 14, 2027$315,000 - $315,000
Mechanisms of cannabinoid-resistance among oral spirochetes
openJul 14, 2027$431,750 - $431,750
Gene Regulation and Physiology of Oral Streptococci
openJun 30, 2030$434,625 - $434,625
ACTL6a ties metabolic reprogramming to cancer stem cell maintenance in oral cavity squamous cell carcinoma
openJul 14, 2027$308,223 - $308,223
Improving the design and implementation of school-based oral health programs using secondary data analysis
openJul 14, 2027$322,000 - $322,000
Development and Validation of an MRI-Compatible Jaw Metabolic Stressor Task
openJul 14, 2027$299,782 - $299,782
Mechanistic investigation of multispecies interactions in clear aligner induced periodontal inflammation
openJul 14, 2027$398,000 - $398,000
Gene Regulatory Mechanisms of Mll4 in Tooth Enamel Development
openJul 14, 2027$320,200 - $320,200
Administrative Supplement for Probabilistic Deep Learning Cervical Lymph-Node Auto-Segmentation For Imaging-enhanced Evaluation of Extracapsular Extension Risk (PDL-CLASIFIER)
openMar 31, 2027$175,256 - $175,256
Optimizing Oral Cancer Screening and Precision Management of Potentially Malignant Oral Lesions
openJul 31, 2027$465,582 - $465,582
Using Novel Machine Learning Approaches to Understand Subgingival Microbiome Heterogeneity in Relation to Health and Disease
openJul 31, 2027$121,630 - $121,630
The ANTENATAL Study: An ecoNomic evaluaTion of pEriodontal treatmeNt in pregnAnt women and identification of responders to Treatment using mAchine Learning"
openMay 31, 2029$383,833 - $383,833
Control of Virulence Properties in the Major Human Oral Fungal Pathogen Candida albicans by the Asc1 Translational Regulator
openJul 31, 2030$40,549 - $40,549
The role of the Foxi3 transcription factor in craniofacial microsomia
openJan 31, 2028$573,768 - $573,768
Characterizing the microbial and inflammatory state within distant clinically healthy tissues in patients with active periodontal disease
openJul 31, 2027$311,000 - $311,000
Evaluating CT/Xray imaging-correlated impedance-based metrics for predictive surgical osseointegration and injury prevention
openJul 31, 2027$220,000 - $220,000
Biomimetic Nitric Oxide and Hydroxyapatite Duo for Advanced Direct Pulp Capping
openJul 31, 2027$408,375 - $408,375
Streptococcus species as potential therapeutics for oropharyngeal squamous cell carcinoma
openJul 31, 2029$592,080 - $592,080
Determining molecular mechanisms of damage and repair in an oral mucosa chip
openJul 31, 2027$306,200 - $306,200
Bioinspired Synthetic High-Density Lipoprotein (sHDL) nanotherapeutics with immunomodulatory and regenerative potential in endodontics
openJul 31, 2027$135,000 - $135,000
Peptide Discovery for Osteogenesis
openJul 31, 2027$300,155 - $300,155
Inhibition of Hedgehog Signaling as a Therapeutic Strategy for OSCC
openJul 31, 2029$616,000 - $616,000
Role of hyaluronan in YAP signaling on TMJ health and pathology
openJul 31, 2027$507,006 - $507,006
Engineering Mechanisms Causing Adverse Biofilm Responses to 3D Printed Titanium Surfaces
openJul 31, 2030$377,030 - $377,030
Ontology-based aPplications of mUlti-discipLinary knowlEdge on orodeNtal Conditions and outcomEs (OPULENCE)
openMay 31, 2030$736,507 - $736,507
Development of an early tooth organoid via human induced pluripotent stem cells
openJul 31, 2027$435,167 - $435,167
Myogenic Mechanisms of Craniofacial Skeletal Muscle Regeneration
openJun 30, 2027$169,992 - $169,992
In Toto Readout of Transcriptomes and Lineage Relationships in Native Craniofacial Tissues
openApr 30, 2030$688,679 - $688,679
The Interplay of Mesenchymal Stem Cells and Neutrophils During Rapid Maxillary Expansion
openJun 30, 2030$136,711 - $136,711
Microphysiological systems to recapitulate and interrogate Sjögren’s disease salivary gland pathogenesis
openJul 31, 2027$432,209 - $432,209
TMJ-on-a-chip for delineating multi-tissue crosstalk in inflammation and pathophysiological mechanical loadings
openApr 30, 2030$745,663 - $745,663
Investigation of New Molecules in Tooth and Root Developmental Anomalies
openJul 31, 2027$297,000 - $297,000
Controlled delivery of mitochondria for craniofacial bone healing
openJul 31, 2027$447,009 - $447,009
KSHV Replication and Trained Immunity
openApr 30, 2030$505,056 - $505,056
Mechanisms sustaining lytic herpesviral infection in the oral cavity
openApr 30, 2030$466,640 - $466,640
Role of Macrophage Migration Inhibitory Factor (MIF) in KSHV-associated Malignancies
openJul 31, 2027$306,000 - $306,000
Lysosome-targeting chimeras degrading immune checkpoint proteins to enhance immunoradiotherapy of head and neck cancer
openJul 31, 2027$129,289 - $129,289
Leveraging Advances in Practices and Outcomes in Cleft Care: The LEAP Study
openJun 30, 2030$1,281,274 - $1,281,274
From Crest to Bone: Understanding neural crest skeletogenic capacity along the neural axis
openJul 31, 2027$162,281 - $162,281
Zinc nanocrystals from zinc tetraammine fluoride for caries arrest and remineralization
openJul 31, 2027$297,711 - $297,711
Developing AI-Derived Multilevel Risk Scores for Oral Cavity and Oropharyngeal Cancer Patients
openAug 7, 2027$325,176 - $325,176
Chemoprevention of Electronic Cigarette Promoted Oral Squamous Cell Carcinoma
openAug 6, 2027$317,000 - $317,000
A Novel Anti-infective Therapy for Treating Periodontitis
openJul 31, 2027$309,038 - $309,038
Molecular Mechanism by which Notch Signaling regulates TMJ Osteoarthritis
openMay 31, 2030$419,379 - $419,379
Development and characterization of metastatic Myb-NFIB fusion adenoid cystic carcinoma cell line models
openAug 7, 2027$451,000 - $451,000
Point of Care Detection of HPV and P16 in Saliva
openJul 31, 2027$1,414,853 - $1,414,853
Impedance-based bone health characterization for predictive osseointegration and patient-specific treatment
openAug 7, 2026$296,171 - $296,171
Validating the hybrid epithelial/mesenchymal state as a biomarker of treatment response and outcomes in head and neck cancer
openMay 31, 2030$702,871 - $702,871
Identifying cellular and molecular signatures from distinct T cell receptor clonotypes associated with favorable immune checkpoint inhibitor responses in HNSCCs
openFeb 28, 2027$750,429 - $750,429
Silver Diamine Fluoride (SDF) and Medicaid Policy: Improving Pediatric Oral Health
openMay 31, 2030$693,179 - $693,179
Modeling Hemifacial Spasm in Mice
openAug 10, 2027$433,657 - $433,657
Exploiting immunostimulatory microbial pattern recognition to improve head and neck cancer therapy
openMay 31, 2030$427,208 - $427,208
Commercialization Readiness Pilot for A Comprehensive Platform for Pediatric Cranial Evaluation
openAug 11, 2027$1,000,000 - $1,000,000
Decoding Neuroimmune Interactions to Enhance Craniofacial Bone Healing
openAug 11, 2027$521,362 - $521,362
Bacteriophages in dental caries: Roles and potential as a therapy
openAug 12, 2027$645,988 - $645,988
Therapeutic mechanisms of iPSC-MSC derived extracellular vesicles on dry mouth caused by Sjorgren's syndrome or radiotherapy
openMay 31, 2030$643,574 - $643,574
Contribution of Truncated TrkB Isoform in Oral Cancer Pain
openMay 31, 2029$654,733 - $654,733
Epstein-Barr virus nuclear antigen 2 in transcription regulation
openMay 31, 2030$450,462 - $450,462
Effectiveness of an Early Intensive Preventive Dental Program by Oncology Providers to Reduce Dental Disease and Improve Compliance in Head and Neck Cancer Patients: OraRad IPDP
openAug 13, 2026$681,331 - $681,331
The Oral Microbiome and Cognitive Function
openAug 13, 2027$332,787 - $332,787
Characterization of two endopeptidases encoded by Streptococcus sanguinis
openAug 13, 2027$426,250 - $426,250
Pre-vascularization of an Integrated 3D Human Osteo-Mucosal Model
openAug 13, 2028$583,826 - $583,826
Advancing the Genomics Knowledge Base for Oral Diseases
openMay 31, 2028$673,091 - $673,091
Oral Health Influences Among Emerging Adult Women of Central and South American ancestry
openApr 30, 2028$235,954 - $235,954
A Novel Immunological-Directed Probiotic for the Treatment of Sjögren’s Syndrome
openAug 13, 2026$429,158 - $429,158
A Pathomimetic Gingiva-on-a-Chip for Assessing Microbiota-Directed Anti-Inflammatory Therapeutics
openAug 13, 2027$442,750 - $442,750
The intersection of AI, clinical practice and health outcomes with linked Medical-Dental electronic records.
openAug 13, 2027$438,768 - $438,768
Investigating the role of ELAVL1 as a post-transcriptional regulator of cranial neural crest development
openAug 14, 2030$50,006 - $50,006
Underscoring human oral host-pathogen interactions and modulation in an immunocompetent in vitro model of early dysbiosis
openAug 14, 2027$540,629 - $540,629
Intraoperative stereo imaging for oral specimen orientation and margin visualization
openAug 14, 2027$452,967 - $452,967
A Team Science Approach to the Co Development of Oral Mucosa for Therapeutic Purposes
openMay 31, 2030$1,240,877 - $1,240,877
Frequent Standardized Oral Care Using Human Milk to Reduce Gastrointestinal Dysbiosis and Inflammation to Improve Health Outcomes and Reduce Cost in Preterm Very Low Birth Weight Infants
openJul 31, 2027$511,706 - $511,706
Establishing a novel 13C-labeled metabolite library for the study of dental caries
openJul 31, 2027$597,807 - $597,807
Advancing Craniosynostosis Treatment (ACT) Rare Diseases Consortium Career Enhancement Core
openMay 31, 2030$133,466 - $133,466
Targeting CISD1-mediated ferropoptosis in head and neck cancer
openAug 19, 2027$418,000 - $418,000
Targeting TRPC1: A Novel Approach to Treat Oral Cancer
openAug 19, 2027$315,000 - $315,000
Use of Apatinib-nanosponge conjugate to reduce post-radiation induced oral cavity and salivary fibrosis.
openAug 19, 2026$298,942 - $298,942
Small Molecule Inhibitors Against HPV-Induced Orophageal Cancers
openJul 31, 2027$433,125 - $433,125
Dissecting CCL5 contribution to antigen specific T cell responses in head and neck cancers
openAug 20, 2029$3,742,682 - $3,742,682
Fibronectin Modulation of Oral Cancer Nociception
openAug 20, 2027$672,660 - $672,660
Bitter taste receptors in oral cancer tumor-associated macrophages
openMay 31, 2030$511,578 - $511,578
Tissue-immunoengineering of TMJ neodisc implants
openMay 31, 2030$589,135 - $589,135
Senescent periodontal ligament cells as a potential therapeutic target for age-associated periodontitis
openMay 31, 2030$385,116 - $385,116
Investigating the role of ESRP2 in craniofacial development using the cleft primary palate (cpp) avian model.
openAug 23, 2028$50,324 - $50,324
Low-Burden High Fidelity Obstructive Sleep Apnea Screening Using Oral Cavity Images
openAug 21, 2026$305,746 - $305,746
AntiXero: An extended duration solution for cancer-associated dry mouth.
openAug 24, 2026$406,496 - $406,496
Determining the role of Raftlin-2 in neural crest cell specification and migration
openAug 31, 2028$50,338 - $50,338
Targeting Succinate Signaling for Innovative Pain Relief in Oral Cancer.
openAug 31, 2029$3,892,146 - $3,892,146
Restoration of non-cavitated carious lesions in enamel using nano-fluorapatite particles
openAug 31, 2026$270,594 - $270,594
Engineering Cell Fate in Salivary Gland Development
openAug 31, 2028$249,000 - $249,000
Piezo1- Mediated Type H Vessel Formation in Periodontitis
openAug 31, 2028$101,356 - $101,356
Gene regulatory programs underlying differences in neural crest developmental potential in the head and neck
openAug 31, 2028$50,338 - $50,338
SCH: Multidimensional Microfluidic Salivary Sensor with Adversarial Knowledge Distillation for Point-of-Care Assessment of Periodontitis and Comorbidities
openAug 31, 2026$287,077 - $287,077
Multimodal Multi-Electrode Array (MEA) for Probing Tooth Root Organoid Maturation and Sensory Innervation
openAug 31, 2027$50,338 - $50,338
Caregiver-implemented early speech and language intervention for toddlers with cleft palate
openAug 31, 2027$336,748 - $336,748
Nanodroplet Infused Analgesic-Wafer for Transmucosal Opioid-free Treatment of Subacute Oral Pain
openAug 31, 2027$413,298 - $413,298
Cellular heterogeneity and niche regulation in TMJ
openMay 31, 2030$368,438 - $368,438
Redefining Dental Imaging: Low-Cost MRI with Relaxed Field Requirements
openAug 31, 2026$341,970 - $341,970
Ultrasensitive detection of circulating DNA methylation for head and neck cancer prognosis
openMay 31, 2030$716,123 - $716,123
Bioinformatics/data science Core (BDSC)
openJun 30, 2030$869,004 - $869,004
Defining TMJ cartilage progenitors and their regulatory niche for TMJ regeneration
openSep 10, 2027$655,455 - $655,455
Identifying Subgroups of Adolescents with Chronic Temporomandibular Disorder Pain to Guide Personalized Treatment
openSep 10, 2027$310,295 - $310,295
Broader Evaluation of TMD Treatment Efficacy and Response (BETTER TMD)
openJun 30, 2030$896,543 - $896,543
Structural-functional studies of gingipain biogenesis and localization
openSep 10, 2027$358,823 - $358,823
Targeting GTP Cyclohydrolase 1 for treating chronic orofacial pain
openAug 31, 2026$392,312 - $392,312
Dichotomy of Phosphate Actions in Periodontal Health
openSep 14, 2027$454,002 - $454,002
Medicaid Accountable Care Organizations and Children's Oral Health and Access to Care
openSep 16, 2027$728,647 - $728,647
miR6891-5p-regulated X skewing in Sjögren's Disease: molecular mechanism, reversal strategies, and clinical significance
openSep 18, 2027$363,221 - $363,221
Aging, Sex Bias, and CD8 T Cell Exhaustion in Salivary Gland Inflammation
openSep 18, 2027$468,875 - $468,875
Analysis of high dimensional genomic dataset to reveal mechanistic insights on divergent outcomes of head and neck cancer using system biology modeling coupled with experimental validation
openSep 18, 2028$1,899,042 - $1,899,042
360 Whole-Person/Healthcare/Community TMD Research
openJun 30, 2030$754,425 - $754,425
Deciphering transcription factor spatiotemporal and dosage effects in face development
openSep 29, 2028$78,840 - $78,840
Investigating the molecular etiology of Keratinocyte Differentiation Factor 1 (KDF1) in disease phenotypes of the ectoderm.
openNov 30, 2027$50,338 - $50,338
Role of BAP1 in the biphasic life cycle of KSHV
openDec 31, 2028$45,037 - $45,037
Integrative Predictors of Temporomandibular Degenerative Joint Disease
openMay 31, 2030$698,865 - $698,865
Harnessing Knowledge from the Social and Behavioral Sciences to Develop Sociobehavioral Interventions that Address Children's Oral Health Disparities
openDec 31, 2026$18,000 - $18,000
Elucidating the effects of sublingual tablets containing buprenorphine on dental caries, and development of a novel formulation.
openDec 31, 2028$47,454 - $47,454
Disease Etiology and Structural Proteomics of Jbts17
openDec 31, 2028$41,058 - $41,058
Microfracture-based Repair for Temporomandibular Joint Osteoarthritis
openJan 15, 2027$78,840 - $78,840
Voice-activated antibacterial piezoelectric composites for dental restorations
openJan 15, 2028$435,875 - $435,875
Determining the Impact of Metabolic Syndrome on the Oral Microbiome and Periodontal Health Using a Longitudinal Systems Biology Approach
openDec 31, 2030$699,184 - $699,184
Investigating the roles of extracellular pyruvate in regulating Streptococcus mutans physiology and stress resistance
openJan 15, 2028$419,375 - $419,375
Cartilage and bone of the lower jaw in development and disease
openJan 31, 2027$760,727 - $760,727
Pharmacological inhibition of ENPP1 to promote cementum regeneration and periodontal return to function
openJan 31, 2028$469,207 - $469,207
The Development of an early detection tool for oral-dental radiation induced injury
openJan 31, 2029$38,901 - $38,901
Probing the role of Selenomonas sputigena in supragingival biofilm spatial structuring and virulence
openJan 31, 2029$249,000 - $249,000
Transcriptional regulatory Mechanisms of Salivary gland Regeneration in a defined genetic model
openJan 31, 2028$440,275 - $440,275
An Atlas of Bacterial Physiology in the Human Oral Cavity
openFeb 3, 2028$340,149 - $340,149
Radiation-guided theranostic agents to monitor response to oral cancer treatment
openFeb 5, 2028$427,625 - $427,625
PDGFRbeta-mediated skeletal-vascular crosstalk in calvarial bone marrow development
openFeb 14, 2028$341,000 - $341,000
Photochemical Tissue Passivation (PTP) to Reduce Temporomandibular Joint (TMJ) Osteoarthritis (OA)
openFeb 14, 2028$408,951 - $408,951
Treatment for Peri-implantitis via Local Immunomodulation and Effect on the Microbiome
openJan 31, 2031$679,631 - $679,631
Role of tissue homeostasis in Sjogren's disease
openJan 31, 2031$527,732 - $527,732
Investigation of Key Nicotinamide Adenine Dinucleotide Metabolism Pathway Roles in Support of Epstein-Barr Virus Replication
openFeb 29, 2028$135,000 - $135,000
Engineered Synthetic Low-Density Lipoprotein Nanoparticles for Enhanced Cancer Immunotherapy in Head and Neck Cancer
openFeb 28, 2031$644,452 - $644,452
Uncovering interactions between bioderived nanomaterials and water in novel dental adhesives: strategies for reduced moisture sensitivity
openFeb 29, 2028$298,613 - $298,613
Developmental Systems Genomics of morphogenetic timing and facial shape variation
openFeb 28, 2031$795,730 - $795,730
Elucidating the etiology for Schneckenbecken dysplasia, a rare disease, using a vetrebrate model system
openFeb 28, 2027$154,000 - $154,000
Neuroimmunology regulating reparative dentinogenesis
openFeb 28, 2031$690,195 - $690,195
The Role of MK2 on head and neck cancer cell migration, invasion, and metastases
openFeb 28, 2031$693,365 - $693,365
Pathogenesis, Phenotypic Variation, and Prevention of Craniofacial Anomalies
openFeb 28, 2031$371,250 - $371,250
Revealing the Trajectory and Critical Roles of Retinoic Acid in Ameloblast Differentiation
openFeb 28, 2028$312,000 - $312,000
Elucidating subclonal evolution and fitness dynamics in oral carcinogenesis
openFeb 28, 2031$735,436 - $735,436
Regulation of early mandibular morphogenesis by the homeobox protein MSX1
openFeb 28, 2031$449,886 - $449,886
Workflow Optimization for School-based Preventive Oral Health Services Delivery
openMar 4, 2029$555,081 - $555,081
2026 Craniofacial Morphogenesis and Tissue Regeneration Gordon Research Conference and Gordon Research Seminar
openMar 5, 2027$23,000 - $23,000
Computational methods for benchmarking and development of best practices for virus discovery and characterization in the HVP consortium
openJan 31, 2030$563,429 - $563,429
Hiding in plain sight: integrating AI with targeted bench methods to discover and characterize viruses in the human body
openJan 31, 2030$423,366 - $423,366
Function-based annotation and classification of uncharacterized eukaryotic viruses in the human virome
openJan 31, 2030$582,838 - $582,838
Developing computational, experimental and ecological approaches to study integrated phages and their hosts
openJan 31, 2030$539,000 - $539,000
Leveraging primary cell and organoid culture to identify and map the human virome
openJan 31, 2030$587,718 - $587,718
Unraveling the Regulation of Transcription and Activity of Calcium Transporter SLC24A4 in Enamel Formation
openMay 31, 2027$451,000 - $451,000
Investigating the Role of Histamine and HRH1 in Mucus Secretion in the Salivary Glands
openAug 31, 2028$75,852 - $75,852
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Total Opportunities306
Grants306
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