Funding Organization
National Institute of Allergy and Infectious Diseases
1000 opportunities
About
No description available for this funder.
Grants (1000)
Mechanisms of HBx Recognition and Epigenetic Regulation of HBV cccDNA
openMar 29, 2029$50,114 - $50,114
Defining molecular determinants of resident memory T cell differentiation and persistence
openMar 31, 2030$36,673 - $36,673
Implementing novel CRISPR screening models to inform HIV cure strategies by characterizing primary human CD4 T cell resistance to CD8 cytotoxicity
openMar 31, 2029$50,114 - $50,114
Nonpeptidergic neurons suppress cutaneous inflammation via glutamate release
openMar 31, 2030$55,114 - $55,114
Investigating the Role of S. aureus Citrate Metabolism in Prosthetic Joint Infection
openMar 31, 2028$41,509 - $41,509
Investigating the cellular and molecular mechanisms of periventricular inflammation in neuroinflammatory CNS
openMar 31, 2029$35,448 - $35,448
Exploring the Impact of Paternal Immune Activation on Offspring Immunity to Viral Infection
openMar 31, 2028$50,114 - $50,114
Understanding the mechanism of action of repurposed antihypertensive drugs against Borrelia burgdorferi
openMar 31, 2029$46,302 - $46,302
Exploring the targeting and function of mitochondrial gasdermin D in macrophage-driven hyperinflammation
openMar 31, 2028$50,114 - $50,114
A deep mutational scan of the HIV-1 capsid core.
openMar 31, 2030$55,114 - $55,114
Exacerbation of Coxsackievirus B3-Induced Pancreatitis by NOD2 Autoregulation Across the Gut-Pancreas Axis
openMar 31, 2029$76,300 - $76,300
Investigating Relationships of the Upper Airway Microbiota with SARS-CoV-2 Susceptibility and Coronavirus Disease 2019 Disease Presentation
openMar 31, 2028$34,934 - $34,934
Elucidating the molecular mechanisms underlying defensosome biogenesis and release
openMar 31, 2029$50,114 - $50,114
The Role of Type I Interferon in Murine Roseolovirus Induced Autoimmune Gastritis
openJan 31, 2029$36,673 - $36,673
Regulation of spore germination by an intrinsically disordered protein
openMar 31, 2029$46,302 - $46,302
Role of Arid1a in NK cell development and antiviral immunity
openApr 2, 2029$46,564 - $46,564
Novel Gene Variants of ZFYVE21 and Dysregulated Innate Immunity
openMar 31, 2031$778,828 - $778,828
Investigating the impact of type I IFN signaling on regulatory T cell function during mucosal HSV-2 infection
openApr 7, 2028$49,343 - $49,343
Dissecting the protective and pathogenic functions of Tbet+CD11c+ B cells in differing inflammatory environments
openApr 6, 2029$50,114 - $50,114
Deciphering Residual Malaria Mechanisms in the Peruvian Amazon to Inform Novel and Effective Control Strategies
openMar 31, 2031$580,306 - $580,306
AAV-delivered meganucleases for durable control of genital HSV disease
openMar 31, 2028$232,558 - $232,558
Consequences of mast cell activation and complement dysregulation in eosinophilic esophagitis
openMar 31, 2031$207,995 - $207,995
RNA Ribosylation's Role in Viral RNA Biology and Innate Immunity
openMar 31, 2028$229,714 - $229,714
Immunogenicity and Safety of High-Dose vs. Standard-Dose Influenza Vaccines Administered Over Consecutive Seasons to Lung Transplant Recipients
openMar 31, 2031$887,964 - $887,964
Examining the mechanisms underlying Libby Amphibole associated autoimmunity
openMar 31, 2030$138,803 - $138,803
Impact of Host Genetic Variants on Regulating Chikungunya Virus-Induced Disease
openMar 31, 2028$229,360 - $229,360
Transcriptional Mechanisms that Catalyze Dysregulated Type 17 Mucosal Inflammation via Innate Lymphoid Cells
openMar 31, 2031$201,744 - $201,744
Impact of Mechanical Circulatory Support and Microbiome Change on Outcomes in Heart Transplant Recipients
openMar 31, 2031$196,020 - $196,020
Human Intestinal Organoids as a Model for Acute GI-ARS
openMar 31, 2031$560,175 - $560,175
Mapping the determinants of bedaquiline resistance in Mycobacterium tuberculosis
openMar 31, 2028$403,756 - $403,756
Ultra-long-acting in-situ forming implant (ISFI) as a subcutaneous injection for prevention of HIV and unplanned pregnancy
openMar 31, 2028$1,106,984 - $1,106,984
Novel Pediatric TB Diagnostics using Host and Microbial Biomarkers
openMar 31, 2028$210,302 - $210,302
Epigenetic regulation of neo-sex chromosomes in filarial parasites
openMar 31, 2028$440,211 - $440,211
Understanding Multidrug-Resistant Pathogen Infections and their Treatment with Antibiotics and Bacteriophages
openMar 31, 2028$161,244 - $161,244
The role of ZBP1 in controlling HSV-1 pathogenesis
openMar 31, 2031$660,723 - $660,723
Determinants of viral assembly and infectivity within the Ebola virus VP24 protein
openMar 31, 2031$843,182 - $843,182
Development of molecular tools and mouse models to study neglected Sindbis virus genotypes and their epidemic potential
openMar 31, 2028$88,250 - $88,250
Mentoring patient-oriented research on point-of-care diagnostics for infectious diseases
openMar 31, 2031$209,758 - $209,758
Molecular Mechanisms of Aire in Transcriptional Regulation
openMar 31, 2028$267,000 - $267,000
Adaptable and hemodynamic Gut-On-VascularNet models to mitigate radiation injury
openMar 31, 2031$608,000 - $608,000
The Use of the Pig-to-Human Decedent Model to Optimize Future Results in Clinical Xenotransplantation Trials
openMar 31, 2031$2,064,597 - $2,064,597
Characterizing a Novel Toxin in Interbacterial Competition Among B. fragilis
openMay 31, 2029$36,673 - $36,673
Acquisition of essential nutrient lysine by Staphylococcus aureus during invasive infection
openMar 31, 2028$50,114 - $50,114
Mechanisms of Nuclear Egress in Gamma-herpesviruses
openMar 31, 2028$46,302 - $46,302
Leveraging Large Language Models for the Design of Monoclonal Antibodies Against Malaria
openMar 31, 2028$282,757 - $282,757
Identifying the functional impact of ZNF688 autoantibodies in oral lupus lesions
openMar 31, 2027$160,100 - $160,100
Immune regulatory role of reactive oxygen species (ROS) in sepsis
openMar 31, 2031$760,700 - $760,700
Modeling Dirty Timestamp Mice to Assess the Impact of Perinatal Exposure to Diverse Pathogenic Microbes on the Functional Programming of Group 1 ILCs
openMar 31, 2028$411,078 - $411,078
Modeling the Vaginal Microbiome: Predicting BV Recurrence and Identifying Preventative Targets
openMar 31, 2028$427,625 - $427,625
Interleukin 33 signaling beneficially regulates pathologic glia in multiple sclerosis
openMar 31, 2031$157,788 - $157,788
Unique Antibody Structural Variegation Mechanisms
openMar 31, 2031$976,318 - $976,318
Protective mRNA Vaccines Against Tuberculosis
openMar 31, 2031$717,003 - $717,003
Interplay of heterosexual male-female partner microbiomes, Chlamydia trachomatis and transmission
openMar 31, 2031$816,421 - $816,421
Reassessing West Nile virus action thresholds for improved disease control
openMar 31, 2028$436,157 - $436,157
Development of a Humanized IL33 Mouse
openMar 31, 2028$174,824 - $174,824
Inter-strain recombinants of human cytomegalovirus as an in vitro model of in vivo genetic diversity.
openMar 31, 2028$147,000 - $147,000
Enhancing Host Defense Against Bacterial Pneumonia in Lipodystrophy: Evaluating the Therapeutic Potential of Leptin and Tirzepatide
openMar 31, 2028$429,000 - $429,000
A Cluster Randomized Stepped-Wedge Effectiveness-Implementation Trial of a Patient Decision Aid to Increase Sexually Transmitted Infection Testing in the Emergency Department: The STIckER Trial
openMar 31, 2031$872,037 - $872,037
Serotype re-emergence and vaccine impact in the era of next-generation pneumococcal vaccines
openMar 31, 2031$792,513 - $792,513
Development and Support of the Pathway Tools Software
openMar 31, 2030$1,219,508 - $1,219,508
Defective HIV-1 proviral abundance and their immune effects in children and adolescents living with perinatal HIV-1
openMar 31, 2031$779,616 - $779,616
Microbial drivers of oral vaccine failure
openMar 31, 2028$242,250 - $242,250
Role and regulation of methylarginine effector TDRD3 in T cell immunity
openMar 31, 2031$794,183 - $794,183
Development of full thickness human skin model for investigating the mechanism(s) of radiation induced skin injuries and therapeutics development
openMar 31, 2031$556,457 - $556,457
Novel Long-Acting HBV Capsid Assembly Modulators
openMar 31, 2028$954,603 - $954,603
Understanding the mechanisms of maternal antibody interference with oral vaccination
openMar 31, 2031$653,742 - $653,742
Advancing iPSC-derived Thymic Epithelial Cells as Cell Therapy for T Cell Immune Reconstitution in Vulnerable Populations(original application ID AI190181-01)
openMar 31, 2031$809,250 - $809,250
Advancing Analytical Tools to Quantify and Mitigate the Risk for Transitioning from Episodic to Endemic Transmission for Emerging Infections
openMar 31, 2031$787,837 - $787,837
Unraveling the Biosynthesis of Aromatic Virulence Factors in Pseudomonas aeruginosa
openMar 31, 2029$470,978 - $470,978
Development of broadly protective Lassa vaccines using the Pichinde virus vector
openMar 31, 2028$192,500 - $192,500
Understanding carnitine reprogramming in sepsis
openMar 31, 2031$194,904 - $194,904
Discovery and Development of Novel Antimalarial Drugs
openMar 31, 2031$791,611 - $791,611
Mechanisms of respiratory viral infections in hospitalized children
openMar 31, 2031$598,906 - $598,906
Lipidomic discovery of physiological CD1 antigens and blockers for human T cells
openMar 31, 2031$893,459 - $893,459
Development of 3D Multi-cellular Cardiac Tissues for Modeling Delayed Radiation-induced Injury
openMar 31, 2031$538,838 - $538,838
A Sicangu-driven social network strategy for syphilis prevention
openMar 31, 2028$417,567 - $417,567
Cytosolic DNA sensing pathway regulation via non-canonical NF-kB signaling
openMar 31, 2031$372,997 - $372,997
Mechanisms of Macrophage Manipulation by pathogenic SFG Rickettsia: Role of Mitochondrial and Immune Pathways
openMar 31, 2027$440,949 - $440,949
Targeting Evasion Factors: Discovery of novel antibodies for durable suppression of HSV reactivation
openMar 31, 2028$215,758 - $215,758
A mouse model to analyze Foxp3+ TFH cells
openMar 31, 2028$158,500 - $158,500
Omics/Clinical Core
openMar 31, 2027$311,474 - $311,474
Research Project 1: Epidemiology of malaria species and their natural history in human hosts
openMar 31, 2029$90,180 - $90,180
Correlates of protective immunity to HCV and rational vaccine design: Project 1
openMar 31, 2027$143,462 - $143,462
Novel Mechanisms of Genetic Errors of Immunity
openMar 31, 2030$2,483,910 - $2,483,910
Illuminating pediatric immunology through genetics
openMay 31, 2030$533,819 - $533,819
Statistical and Data Management Core
openJul 31, 2030$500,697 - $500,697
Pediatric Fungal Network's (PFN) STudy of Rare Invasive Fungal DisEases in Immunocompromised Pediatric Patients (STRIDE) Career Enhancement Core
openJul 31, 2030$138,924 - $138,924
Targeted therapy platform for eliciting memory-like NK cell responses
openMar 31, 2028$146,948 - $146,948
The impact of low-abundance commensals on gut colonization resistance
openMar 31, 2028$434,090 - $434,090
Development of new genetic tools for selective targeting plasma cells
openMar 31, 2028$161,500 - $161,500
Decoding the glycan forms of glycoRNA-L and glycoRNA-S from leukocytes
openMar 31, 2028$157,500 - $157,500
Development of a novel Guinea pig model that mimics human relapsing fever disease.
openMar 31, 2028$160,500 - $160,500
A Transposon-based Gene Drive to Combat Antimicrobial Resistance
openMar 31, 2031$171,046 - $171,046
The interplay of protein secretion and lipid virulence factors in host immune suppression by Mycobacterium tuberculosis
openMar 31, 2031$756,714 - $756,714
Molecular mechanisms by which S. aureus alpha-toxin impairs the antigen-specific T cell response
openMar 31, 2031$664,076 - $664,076
Effects of oxygen and bile acid processing on the small intestinal microbiome and colonization resistance
openMar 31, 2028$423,500 - $423,500
Inhibitors of the Reverse Transsulfuration Pathway as a New Treatment for Helicobacter pylori Infection
openMar 31, 2028$481,250 - $481,250
Mapping anti-filovirus humoral immune responses in broadly seroreactive individuals
openMar 31, 2028$279,000 - $279,000
Ex Vivo Delivery of Viral-Mediated Gene Therapy for the Amelioration of Post-Transplant Rejection
openMar 31, 2031$597,613 - $597,613
Mechanisms of cryptococcal IRIS
openMar 31, 2031$749,353 - $749,353
Identification and elimination of antigen-specific expanded clones
openMar 31, 2028$427,438 - $427,438
Phase 1b/2a Evaluation of the Safety and Tolerability of SYN-004 in Adult Allogeneic Hematopoietic Cell Transplantation (allo-HCT) Recipients
openMar 31, 2031$919,820 - $919,820
Maternal vaccination to prevent Klebsiella pneumoniae gut colonization and neonatal sepsis
openMar 31, 2031$726,966 - $726,966
Early regulation of T follicular helper cell differentiation via stroma-derived Notch signals
openMar 31, 2028$50,114 - $50,114
Regulation of donor specific antibody production
openMar 31, 2031$690,359 - $690,359
Endogenous Retroviruses and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
openMar 31, 2031$388,229 - $388,229
Exploiting symbiosis to identify novel antifungals to combat emerging drug-resistant pathogens
openMar 31, 2028$411,078 - $411,078
Regulatory T Cells and Lymphatic Endothelial Cells: Regulatory Interactions for Migration and Suppression
openMar 31, 2031$559,800 - $559,800
Identification and Investigation of CD4+ T cell Clonotypes Comprising a Polyclonal Repertoire Against Aeroallergen in a Murine Model of Allergic Asthma
openMar 31, 2028$421,098 - $421,098
Determining the role of micronutrient deficiency in the immune response to oral rotavirus vaccine in a low-resource setting.
openMar 31, 2028$228,000 - $228,000
Time resolved structural analyses of β-lactam/β-lactam inhibitor binding to AmpC
openMar 31, 2031$799,572 - $799,572
The upper intestinal environment and mediators of human cholera severity
openMar 31, 2031$581,755 - $581,755
A Single Long-Acting Injection For HBV Treatment Using Novel Entecavir Prodrugs For PWLH
openMar 31, 2031$899,741 - $899,741
Vaccine Strategies for Preventing Pandemic Influenza Viruses
openMar 31, 2031$799,792 - $799,792
Immune homeostasis during Borrelia burgdorferi infection
openMar 31, 2031$700,997 - $700,997
Passive immunization to prevent vertical papillomavirus transmission in a preclinical mouse model
openMar 31, 2028$234,900 - $234,900
Caregiver Beliefs and Psychosocial Experiences Related to Emerging Treatment Options for Children with Food Allergy
openMar 31, 2028$182,000 - $182,000
Genetic and functional dissection of tissue-infiltrating and age-associated B cells in murine lupus
openMar 31, 2031$499,175 - $499,175
Decoding cellular networks governing respiratory mucosal IgA immunity
openMar 31, 2031$773,388 - $773,388
Human Airway Macrophage Immunity in Tuberculosis: Defining Early Determinants of Infection
openMar 31, 2031$757,038 - $757,038
Speeding Immune Reconstitution after Thymus Transplantation
openMar 31, 2028$444,125 - $444,125
Multiplex binding antibody assay for confirmatory HSV-1/2 serological diagnosis
openMar 31, 2028$270,591 - $270,591
Novel Genetic Approaches to Elucidate Critical Signaling Pathways in Leishmania donovani
openMar 31, 2028$429,000 - $429,000
AI-powered multimodal precision sensing system to track tick phenotypic responses in natural and simulated environments
openMar 31, 2028$415,584 - $415,584
Enhancing Influenza Vaccines through Genetic Surveillance: Can Better Antigenic Match Improve Population Health?
openMar 31, 2031$182,422 - $182,422
A multi-biologic, AAV-deliverable HIV-1 functional cure
openMar 31, 2031$889,519 - $889,519
Elucidating how environmental perturbations determine the duration of enteric viral infection
openMar 31, 2031$627,483 - $627,483
Identification of Host Factors that Mediate the Nuclear Retention of Unspliced and Partially Spliced HIV-1 Transcripts
openMar 31, 2028$427,626 - $427,626
Investigating the developmental and transcriptional bases for distinct functions of IL-10+ and IL-10− Treg cells
openMar 31, 2028$167,951 - $167,951
Characterizing autoreactive B cells and their roles in the pathogenesis of SLE using immune organoids
openMar 31, 2028$127,926 - $127,926
Long-noncoding RNAafu-182- A novel regulator of fungal triazole tolerance
openMar 31, 2031$418,378 - $418,378
Pathogenesis of S. aureus thymidine-dependent small-colony variants
openMar 31, 2028$533,850 - $533,850
Assessing the tolerability and versatility of the new Spytag003/Spycatcher003 as a novel bio-conjugation system for displaying protein antigens on the surface of bacteriophage VLPs
openMar 31, 2029$587,528 - $587,528
Defining the T cell state that sustains chronic allergic disease
openMar 31, 2031$193,600 - $193,600
Structure and ligand binding of receptor adenylate cyclase from Trypanosoma brucei
openMar 31, 2028$157,500 - $157,500
Defining a Minimal Sequential Infection Model to Mature Mouse Immune Responses
openMar 31, 2028$456,500 - $456,500
Identification of bacterial isolates and communities that influence male life history traits and mating success among genetically diverse Ae. aegypti mosquitoes
openMar 31, 2031$525,789 - $525,789
Transforming ANA Testing: Leveraging Epidemiology and AI to Detect Autoimmune Disease
openMar 31, 2031$800,097 - $800,097
Dissecting the Contribution of Neutrophils to Diabetes/Tuberculosis Comorbidity
openMar 31, 2028$259,125 - $259,125
Antibody signatures of HIV treatment effectiveness: toward low-cost rapid tests for treatment monitoring
openMar 31, 2031$841,719 - $841,719
Novel structural and functional insights into T cell metabolism in healthy and disease states
openMar 31, 2027$50,114 - $50,114
Post-initiation control of Pseudomonas aeruginosa exopolysaccharide biosynthesis operons
openMar 31, 2028$439,094 - $439,094
Identification of Ancient Antiviral Defenses Using Viral Ubiquitination Modulators
openMar 31, 2028$249,000 - $249,000
Coreceptor therapy-induced de-differentiation of autoreactive Tfh
openMar 31, 2028$427,625 - $427,625
Genetic and Immunological Investigation of ABCF1 in Celiac Disease and Autoimmunity
openMar 31, 2031$661,009 - $661,009
Defining Particle-Associated Rotavirus NSP4
openMar 31, 2028$240,000 - $240,000
Leveraging phenazine cycling to understand maintenance metabolism in Pseudomonas aeruginosa
openMar 31, 2031$711,488 - $711,488
Developing a Molecular Taxonomy for Immune-Mediated Diseases
openMar 31, 2031$641,889 - $641,889
Light-Assisted Drying: A Novel Method for Stabilizing Inactivated Poliovirus Vaccine in a Sugar Glass for Room-Temperature Storage
openMar 31, 2028$142,910 - $142,910
Comparison of adaptive immunity between different Salmonella serovers
openMar 31, 2028$412,206 - $412,206
Defining the Molecular Epidemiology of Leishmaniasis in Texas Through a One Health Approach.
openMar 31, 2028$461,187 - $461,187
House dust-mite allergen-specific T cell subsets in allergy and asthma
openMar 31, 2031$536,810 - $536,810
Multi-omics Analysis of Bacteria-Host Interactions in Brugia malayi, a Medically Important Nematode with a Wolbachia Endosymbiont
openMar 31, 2031$678,218 - $678,218
N Protein Nexus: Rewiring Host Translation Machinery for SARS-CoV-2's Early Replicative Advantage
openMar 31, 2028$213,048 - $213,048
Ecology of Plasmodium malariae transmission in Cameroon
openMar 31, 2028$88,560 - $88,560
Role of GLI2 in antibody production
openMar 31, 2029$568,367 - $568,367
Systematic exploitation of synergy to improve tuberculosis therapy.
openMar 31, 2031$698,387 - $698,387
Characterization of basophils in urinary tract infections
openMar 31, 2028$458,364 - $458,364
Origin and function of non-canonical CX3CR1+ neutrophils
openMar 31, 2031$735,631 - $735,631
Intracellular bacteria hijack ER-Golgi transport to facilitate infection
openMar 31, 2031$670,881 - $670,881
Virulence mechanisms regulating Candida-driven vaginal epithelial exfoliation
openMar 31, 2031$777,795 - $777,795
Complement convertase imaging techniques for optimization of complement therapeutic amelioration of antibody mediated rejection
openMar 31, 2030$3,267,712 - $3,267,712
Discovery and Optimization of Broadly Protective Merbecovirus Neutralizing Antibodies
openMar 31, 2031$829,735 - $829,735
Passive immunotherapy for measles infection
openMar 31, 2031$855,113 - $855,113
Mechanisms of food-specific antibody induction in the gut
openMar 31, 2031$493,889 - $493,889
DNA ADP-ribosylation in the bacterial-phage arms race
openMar 31, 2031$638,220 - $638,220
Elucidating the role of genome organization in cDC1 development
openMar 31, 2028$162,000 - $162,000
Impact of environmental stress-induced adaptive immune responses on tissue physiology and tumorigenesis.
openMar 31, 2028$162,000 - $162,000
Identifying signaling networks that contribute to Th17-mediated neuroinflammation
openMar 31, 2031$762,086 - $762,086
Complement-mediated clearance of extracellular mitochondria
openMar 31, 2028$485,375 - $485,375
Modulation of HIV immune control by HLA-E-VL9 and HLA-E-VL9 binding antibodies
openMar 31, 2028$106,164 - $106,164
Role of myeloid KLF2 in the neonatal innate immune response
openMar 31, 2031$165,240 - $165,240
Proximal regulation of innate immune signals in ischemia reperfusion injury
openMar 31, 2028$184,000 - $184,000
Delving into peptide specificity of NK inhibitory receptors
openMar 31, 2028$423,500 - $423,500
Regulation of Filovirus mRNA translation
openMar 31, 2028$204,375 - $204,375
Antimicrobial Polymers for Treatment of Multidrug-Resistant Wound Biofilm Infections
openMar 31, 2030$2,641,186 - $2,641,186
HIV-1 antibodies in the presence of tuberculosis and other coinfections
openMar 31, 2031$872,596 - $872,596
Peptide-conjugated phosphodiamidate morpholino oligonucleotide (PPMO)-based henipavirus therapeutics
openMar 31, 2028$475,339 - $475,339
The role of organelle contact sites in macrophage antifungal responses
openMar 31, 2028$194,400 - $194,400
Aptamer tools for the study of HIV capsid structure, function, and interactions.
openMar 31, 2031$538,501 - $538,501
Cell polarity in the obligate intracellular pathogen Rickettsia parkeri
openMar 31, 2028$423,355 - $423,355
Rapid Cell-Based UTI Diagnosis and Antibiotic Selection Test
openMar 31, 2030$617,438 - $617,438
Deciphering the activation mechanisms and immune functions of GSDMC
openMar 31, 2030$2,469,932 - $2,469,932
A Microfluidic-Free Droplet Technology for Rapid and Quantitative Airborne Pathogen Monitoring
openMar 31, 2028$451,000 - $451,000
Generation of a non-cleavable allele of Pik3ip1/TrIP
openMar 31, 2028$135,586 - $135,586
Dissection of Shigella pathogenesis in vivo using a new oral infection mouse model
openMar 31, 2031$751,663 - $751,663
Development of a therapeutic antibody cocktail against New World Arenaviruses
openMar 31, 2031$923,708 - $923,708
A novel pentavalent circular RNA-based EBV vaccine
openMar 31, 2031$932,172 - $932,172
Establishing the etiology of chronic placental villitis of unknown etiology
openMar 31, 2031$689,081 - $689,081
Dissecting the intrinsic role of SLC4A2 in the development of liver inflammation in a mouse model of PBC
openMar 31, 2027$164,000 - $164,000
Dissecting the impact of gut evolution on Klebsiella pneumoniae pathogenesis.
openMar 31, 2028$435,875 - $435,875
Impact of regulatory dendritic cells in neonatal immune responses to Influenza infection
openMar 31, 2031$490,611 - $490,611
An Assay for Paenibacillus Detection in Low Resourced Settings
openMar 31, 2028$267,704 - $267,704
Anti-inflammatory effects of reverse transcriptase inhibitors during bacterial infection
openMar 31, 2028$158,800 - $158,800
Human upper airway immune memory kinetics and durability against respiratory pathogens
openMar 31, 2031$159,300 - $159,300
Modeling SARS-CoV-2 variant emergence from immunocompromised hosts
openMar 31, 2031$161,946 - $161,946
Increasing Breadth of Immune Response by Single-Dose Influenza Vaccines
openMar 31, 2031$721,365 - $721,365
Investigating the immunomodulatory role of the Nonclassical MHC Molecule HLA-F in Human Pregnancy
openMar 31, 2031$818,457 - $818,457
Statistical Models for Estimating Spatial and Sub-population HIV Epidemics
openMar 31, 2031$842,720 - $842,720
Neutralizing antibody pressure on the evolution of SARS-CoV-2 variants."
openMar 31, 2031$194,160 - $194,160
Exploration of the bacterial polyadenylase PAP I as an antimicrobial drug target
openMar 31, 2028$430,375 - $430,375
Surveillance of antibiotic resistance in natural commensal Neisseria populations: Reservoirs of resistance for important human pathogens
openMar 31, 2029$561,410 - $561,410
Mentoring in Anti-Infective Clinical Pharmacology and Pharmacometrics
openMar 31, 2031$203,556 - $203,556
Species-specific Yeast RNAi Pesticides for Sand Fly Control
openMar 31, 2028$464,176 - $464,176
Mechanisms underlying Phage-Antibiotic Synergy and Resistance in Daptomycin-Resistant Enterococcus faecium
openMar 31, 2028$455,719 - $455,719
Hijacking the neonatal Fc receptor: the novel biology of arterivirus entry, transmission, and persistence
openMar 31, 2031$615,446 - $615,446
Integrated Program for Cutaneous Immune-Stromal Interactions in SLE (IPCISS)
openMay 31, 2030$1,540,008 - $1,540,008
Program for Resistance, Immunology, Surveillance & Modeling of Malaria in Uganda (PRISM) Renewal
openApr 30, 2029$590,328 - $590,328
Temporal Regulation of mRNA Biogenesis in Immune Responses
openFeb 9, 2027$34,370 - $34,370
Synergistic Nanobodies for Pandemic Preparedness
openJan 31, 2030$876,480 - $876,480
Development and application of pediatric-specific blood transcriptional modules across diverse geographical settings through public data mining
openJan 31, 2027$286,791 - $286,791
Elucidating influenza-induced protection of malaria-associated respiratory distress syndrome in mice
openMar 31, 2027$192,500 - $192,500
Nanobody-mediated proteolysis of Aspergillus fumigatus transcription factors in vitro and in vivo
openJan 31, 2027$197,420 - $197,420
Characterization of TOX isoform-specific roles in T cell and ILC development
openJan 31, 2027$250,500 - $250,500
In vivo functional characterization of a novel protein encoded by a lncRNA
openJan 31, 2027$74,346 - $74,346
Characterization of a novel chimeric autoantigen receptor (CAAR) treatment for Graves' disease
openFeb 23, 2028$440,333 - $440,333
Single-cell transcriptional atlas of Giardia encystation
openJan 31, 2027$218,767 - $218,767
Immunobiology of a novel human DAMP receptor, its murine homolog, & their ligand
openJan 31, 2030$578,093 - $578,093
Characterization of a novel post-transcriptional regulator in P. aeruginosa
openJan 31, 2030$868,776 - $868,776
An integrated multiplexed diagnostic assay targeting fusion lipoproteins and cardiolipin for detection of treponemal and nontreponemal antibodies in syphilis patients
openJan 31, 2029$692,013 - $692,013
Mosquito extracellular vesicles in malaria parasite killing and immune priming
openJan 31, 2030$648,924 - $648,924
Evolved cefiderocol resistance and cross protection
openJan 31, 2030$794,849 - $794,849
Dynamic FOXP3 Expression in the Development of Regulatory T cells from Induced Pluripotent Stem Cells
openJan 31, 2030$196,992 - $196,992
Development of broadly neutralizing human monoclonal antibodies against henipaviruses
openJan 31, 2030$830,098 - $830,098
[18F]fluoromannitol: A novel imaging agent to delineate osteomyelitis in sickle cell disease
openJan 31, 2029$894,735 - $894,735
Mechanisms of STAT1 and STAT3 canonical and persistent activation in physiology and disease
openFeb 28, 2030$639,485 - $639,485
Molecular details of the IgE antibody response to galactose-alpha-1,3-galactose in alpha-gal syndrome
openFeb 28, 2030$753,304 - $753,304
mRNA-Based Vaccines Against Tick Borne Thogotoviruses
openFeb 28, 2027$207,262 - $207,262
Host-Microbe Interactions and SARS-CoV-2 Susceptibility and Symptoms in aNovel Human Challenge Model
openJun 30, 2026$95,750 - $95,750
Development of an ETEC multivalent subunit vaccine using outer membrane vesicles
openFeb 28, 2027$229,500 - $229,500
Active and passive humoral immunity to enteric adenovirus infection in Bangladeshi children
openFeb 28, 2030$192,260 - $192,260
Host heterogeneity affects susceptibility of Babesia microti infection using vector-mediated transmission
openFeb 28, 2027$250,573 - $250,573
Understanding the mechanism of tropism specific immune restriction in HIV infection
openFeb 28, 2030$197,366 - $197,366
Hypoxia morphology of Aspergillus fumigatus impacts diagnostics
openFeb 28, 2027$50,114 - $50,114
A single biosensors for the simultaneous molecular detection of HIV and Hepatitis B and C viruses at resource-limited settings
openFeb 29, 2028$537,619 - $537,619
Membrane Protein Complexes in the M. Tuberculosis Divisome: Structures and Interactions
openFeb 28, 2030$668,549 - $668,549
Care, Review, Assessment and Feedback Tool In Acute Respiratory infections (CRAFT-IAR)
openFeb 28, 2030$873,716 - $873,716
Mechanism of parainfluenza virus genome replication
openFeb 28, 2030$734,184 - $734,184
The Establishment of Lung Resident Self-Antigen-Specific CD4+ Tregs Following Acute Tissue injury
openFeb 28, 2030$194,740 - $194,740
Streptococcus pneumoniae HtrA and its target interactions
openFeb 28, 2027$234,000 - $234,000
The role of PPARd-controlled CIITA/MHCII expression in Treg's function in tumor immunity
openFeb 28, 2027$237,500 - $237,500
Revealing the Mechanisms of Cleaved and Intact GSDMD Pore Formation and Membrane Rupture
openFeb 29, 2028$38,123 - $38,123
Role of PKC Epsilon in Atheroprotection
openFeb 28, 2027$205,000 - $205,000
Biophysical and genetic approaches to uncover ventral disc contractile attachment mechanisms in Giardia
openFeb 28, 2030$718,086 - $718,086
Optimization of UltraPCR for detection of and assessment of treatment outcomes in Trypanosoma cruzi infection
openFeb 28, 2030$504,703 - $504,703
Characterization of innate immune signaling pathways in the tick Ixodes scapularis
openFeb 28, 2030$831,622 - $831,622
Determinants of reservoir contraction and expansion in vivo, ex vivo, and in vitro
openFeb 28, 2030$648,378 - $648,378
Functions of the largest HSV-1 virion protein, pUL36
openFeb 28, 2027$75,175 - $75,175
Reproductive and Child Health StaRR Program
openFeb 28, 2030$402,731 - $402,731
Structural studies of the OrfX-type progenitor toxin complex of botulinum neurotoxin
openFeb 28, 2030$616,816 - $616,816
Mechanisms and Consequences of c-di-GMP Control of Motility and Biofilm Formation
openFeb 28, 2030$774,575 - $774,575
Defining the larval repertoire of Aedes aegypti somatosensory neurons
openFeb 28, 2027$75,418 - $75,418
Handheld and population-based sequencing for rapid detection of new and repurposed drug resistance in M. tuberculosis
openFeb 28, 2027$290,717 - $290,717
Mechanisms of Resistance and Clinical Outcomes of non-Carbapenemase Producing Carbapenem-Resistant Klebsiella pneumoniae Infections
openFeb 28, 2027$259,461 - $259,461
COVID Global Mix - Global Mix / Investigation of COVID-19 Disease Parameters for Transmission Models in Low-Resource Settings
openFeb 28, 2027$48,219 - $48,219
Dissecting innate immune control of intestinal and systemic Yersinia infection
openFeb 28, 2030$1,024,897 - $1,024,897
Metabolic and epigenetic regulation of skin Tregs
openFeb 28, 2030$597,542 - $597,542
Targeting monocyte allorecognition to achieve allograft acceptance
openFeb 28, 2030$612,975 - $612,975
Development of Oral Immunotherapy against Clostridioides difficile Transmission
openFeb 28, 2030$719,022 - $719,022
The role of caspase-3 mediated cleavage of VPS4A in restricting HSV-1
openJun 30, 2029$40,023 - $40,023
Naive CD8 T cell functional heterogeneity
openFeb 28, 2030$658,849 - $658,849
Altered protein structures and neoepitopes in lupus neutrophils from dysregulated splicing of messenger RNA
openFeb 28, 2027$256,808 - $256,808
Statistical methods for TCR-sequencing experiments
openFeb 28, 2027$219,792 - $219,792
Regulation of the HA stem nanoparticle vaccine response by antigen duration
openFeb 28, 2027$228,195 - $228,195
Therapeutic targeting the host hypoxia-response pathway to treat Mucormycosis
openFeb 28, 2030$750,815 - $750,815
Defining successful intrahepatic CD4+ T cell responses against the hepatitis C virus
openFeb 28, 2030$489,389 - $489,389
Nonhuman Primate Core Humoral Immunology Laboratory for AIDS Vaccine Research and Development
openMar 29, 2032$2,523,410 - $2,523,410
Efficient and Long-lived Brain Delivery of Neutralizing Antibodies Against Eastern Equine Encephalitis Virus for Post-exposure Therapy
openMar 31, 2027$240,300 - $240,300
Building tools to study commensal-specific CD8+ T cells in the small intestine
openMar 31, 2027$86,650 - $86,650
Uncovering the proviral role of B cell-intrinsic STAT1 expression during chronic gammaherpesvirus infection
openMar 31, 2028$49,538 - $49,538
Epithelial Immune Cell Interactions in Persistent T2 Inflammation
openMar 31, 2028$247,508 - $247,508
Virologic and immunologic impacts of active viral persistence in lung AMs of HIV-1-infected, cART-suppressed individuals
openMar 31, 2029$152,468 - $152,468
Co-benefits of co-delivery of long-acting antiretrovirals and contraceptives
openMar 31, 2027$329,173 - $329,173
Scaling function-first antibody discovery leveraging memory B cells
openMar 31, 2027$1,000,000 - $1,000,000
Investigating VICE domain functions tied to altered ribosome localization and translational flux during HSV-1 infection
openMar 31, 2027$34,114 - $34,114
Enhanced Antifungal Therapy to Improve Survival in Early Disseminated Cryptococcal Infection
openMar 31, 2028$274,913 - $274,913
A multidisciplinary approach to study ecotypes driving transmission and pathogenesis of Visceral Leishmaniasis (VL) and Post kala-azar dermal leishmaniasis (PKDL) in Eastern Africa
openMar 31, 2027$60,763 - $60,763
Identifying vulnerabilities in the long-lived HIV reservoir to accelerate its decay
openMar 31, 2028$32,698 - $32,698
Revealing the Structural Determinants of TCR Cross-Recognition via Extended Positional Scanning
openMar 31, 2027$78,220 - $78,220
Project 1: Human and Non-human Primate Influenza B-cell Repertoires
openMar 31, 2028$710,000 - $710,000
Molecular analysis of mother-to-child transmission of hepatitis B virus
openMar 31, 2030$621,698 - $621,698
Tropical Medicine Research Center for Talaromycosis in Vietnam
openMar 31, 2027$235,391 - $235,391
Optical Sequencing to Link Quantitative Bacterial Phenotypes to Human Mutations
openMar 31, 2027$199,506 - $199,506
Host Response to Hepatitis Delta Virus Infection
openMar 31, 2027$249,000 - $249,000
Developmental acquisition of memory-phenotype CD8+ T cell function in infection and cancer
openMar 31, 2029$55,114 - $55,114
Core-001
openMar 31, 2029$24,712 - $24,712
The effects of immunosuppression on SARS-CoV-2 persistence, virus genetic diversity and clinical outcomes of COVID-19
openMay 31, 2026$169,500 - $169,500
ICEMR Data Management Core
openMar 31, 2029$27,864 - $27,864
Alphavirus Pathogenesis and Immunity
openMar 31, 2030$782,871 - $782,871
Project-002
openMar 31, 2029$42,210 - $42,210
Understanding and Targeting the Barriers to Effective Malaria Control and Elimination in the Asia-Pacific Region
openMar 31, 2029$191,687 - $191,687
COVID Transmission and Morbidity in Malawi (COVID-TMM)
openMar 31, 2027$81,489 - $81,489
Identification of post-translationally modified antigens using genetic code expansion
openMar 31, 2027$223,451 - $223,451
Influence of hypoxia on the antiviral functions of human intestinal epithelial cells
openMar 31, 2030$646,188 - $646,188
Continuous in vitro culture and genetics of Plasmodium vivax in a bespoke blood cell bioreactor
openMar 31, 2028$406,450 - $406,450
Using Targeted, Controlled High Frequency Energy for Treatment of Onychomycosis
openMar 31, 2028$1,000,000 - $1,000,000
KSHV Infection And Persistence
openMar 31, 2030$857,354 - $857,354
Rapid Antibiotic Susceptibility Testing via Selective Lysis and Nanogap Trapping
openMar 31, 2030$490,093 - $490,093
Mechanisms of central nervous system invasion by the Lyme disease spirochete, Borrelia burgdorferi
openMar 31, 2027$192,500 - $192,500
Trispecific Killer Cell Engager for the Treatment of Systemic Lupus Erythematosus
openMar 31, 2027$235,500 - $235,500
Structural, functional, and microbiological exploration toward synergistic dual aminoglycoside combinations
openMar 31, 2027$237,518 - $237,518
Examining the influence of chromosome copy number on Pseudomonas aeruginosa persisters to fluoroquinolones
openMar 31, 2027$205,000 - $205,000
Interrogation of SidB-dependent septation for echinocandin potentiation in invasive aspergillosis treatment
openApr 14, 2027$40,960 - $40,960
The interplay of maternal antibody and newborn vaccine responses
openMar 31, 2030$793,102 - $793,102
Apolipoprotein E governs lymph node stromal cell function and lipid metabolism during autoimmunity
openMar 31, 2030$189,540 - $189,540
How to build a rib cage for a cell: the patterning, growth, and maturation of the cortical microtubules in Toxoplasma
openMar 31, 2030$563,513 - $563,513
SMART Use of Biologics in Chronic Rhinosinusitis with Nasal Polyposis
openMar 31, 2030$1,498,642 - $1,498,642
Toward field-ready paratransgenesis for malaria: bacterial strain optimization and microbiota interactions
openMar 31, 2030$606,815 - $606,815
Administrative Core - Drivers of influenza A virus transmission in humans
openMar 31, 2030$414,941 - $414,941
Assessing the Mycobacterium tuberculosis carriage state
openMar 31, 2027$187,998 - $187,998
Impact of Vpr-induced epigenetic remodeling on HIV persistence
openMar 31, 2030$610,527 - $610,527
Integrin-mediated regulation of type-1 dendritic cell positioning and function in lymph nodes
openMar 31, 2027$220,625 - $220,625
Evaluating Treatment Efficacy in Canine Visceral Leishmaniasis: The Role of Individual Factors and Co-Infections in Disease Control and Therapeutic Response.
openMar 31, 2027$77,000 - $77,000
The role of Alternaria fungal sensitization in asthma pathogenesis
openApr 30, 2026$175,000 - $175,000
Next Generation Development of Broadly Neutralizing HIV Antibodies for Prevention
openMar 31, 2028$180,640 - $180,640
Oral BCG: Optimizing mucosal vaccination against tuberculosis
openMar 31, 2030$1,162,224 - $1,162,224
Molecular investigations of HIV-1 maturation pathways and inhibitor actions in situ
openMar 31, 2030$859,992 - $859,992
Conserved NO-Binding Cytochromes in Burkholderia pseudomallei and Other Pathogens
openMar 31, 2027$216,165 - $216,165
Developing vaccines against the intracellular and extracellular Lifestages of the Cryptosporidium parasite
openMar 31, 2027$201,875 - $201,875
IL17 Signaling in Monogenic Type 1 Diabetes
openMar 31, 2027$164,000 - $164,000
Development of YK-4-250, a radiation mitigator of GI-ARS
openMar 31, 2030$552,787 - $552,787
Defining the role of the Brucella TIR-NAD hydrolase activity in immunosuppression and pathogenesis
openMar 31, 2027$233,250 - $233,250
Decoding T cell clonotypes, biology and predictive biomarkers associated with immune checkpoint Myocarditis
openApr 30, 2030$858,186 - $858,186
Unraveling the molecular mechanisms of innate immune memory in humans
openApr 30, 2030$735,078 - $735,078
Novel roles of Fc gamma binding protein in colonic host-microbiota interactions
openApr 30, 2027$222,750 - $222,750
Defining the role of the RGS12 locus in macrophage function
openApr 30, 2028$42,885 - $42,885
APOBEC3-driven host mechanism promotes poxvirus diversification to overcome host immune restriction
openApr 30, 2027$221,105 - $221,105
PD-1/PD-L1 signaling at the interface between immune and stem cell crosstalk
openApr 30, 2027$384,250 - $384,250
Microglial immunity in Toxoplasmic encephalitis
openApr 30, 2027$227,018 - $227,018
Identifying metabolic targets to reinvigorate T cell exhaustion
openApr 30, 2027$49,538 - $49,538
Protein display drug ANDI reduces asthmatic airway hyperreactivity
openApr 30, 2027$320,863 - $320,863
Next Generation ELQs for Treatment and Once-Monthly Protection Against Malaria
openApr 30, 2029$587,318 - $587,318
Rapid Point-of-Care Assay for Diagnosis of Neurocysticercosis in Seizure Patients
openApr 30, 2027$123,606 - $123,606
Development of novel multivalent mucosal vaccines for human noroviruses
openApr 30, 2030$798,173 - $798,173
Multidisciplinary studies on overcoming SARS-CoV-2 main protease drug resistance and on fitness costs
openFeb 6, 2028$48,974 - $48,974
Uganda Schistosomiasis Multidisciplinary Research Centre (U-SMRC)
openApr 30, 2027$252,274 - $252,274
Defining a role and functional consequences of the disordered N-terminal domain from the Borna Disease Virus Phosphoprotein
openApr 30, 2028$36,046 - $36,046
Clinical Core
openApr 30, 2026$203,405 - $203,405
Investigating B cell central tolerance to a model commensal antigen
openApr 30, 2027$186,486 - $186,486
Development, Clinical Validation, and Readiness for Implementation of a Novel Mp1p D4 Poin Diagnosis of Talaromycosist of Care Test for Rapid
openApr 30, 2028$138,564 - $138,564
International epidemiology Databases to Evaluate AIDS (IeDEA) Southern Africa.
openApr 30, 2027$221,852 - $221,852
PRESCIENT: A phase IIc, open-label, randomized controlled trial of ultra-short course bedaquiline, clofazimine, pyrazinamide and delamanid versus standard therapy for drug-susceptible tuberculosis
openApr 30, 2027$398,334 - $398,334
Learning from Remission and Relapse in SLE
openApr 30, 2029$90,908 - $90,908
LpxH Inhibitors as Novel Therapeutics Against Multidrug-resistant Enterobacterales
openApr 30, 2030$747,763 - $747,763
A Novel Electrochemical LFA for Diagnosing TB from a Single Drop of Blood
openApr 30, 2027$238,500 - $238,500
Assessing food-specific tolerogenic CD4+ T cells in protection from food allergy
openApr 30, 2027$49,538 - $49,538
Role of WDFY4 in Treg development
openApr 30, 2030$737,502 - $737,502
Randomized Control Trial of Nitazoxanide for the Treatment of Cryptosporidium Infection in Malnourished Children in Bangladesh
openApr 30, 2028$196,370 - $196,370
Human papillomavirus regulation of the Hippo signaling pathway
openApr 30, 2030$533,707 - $533,707
Development of Commensal-Specific T cell Studies
openApr 30, 2027$74,718 - $74,718
STRIVE: Short-Term Research in Immunology and Virology Experience
openApr 30, 2030$105,170 - $105,170
Harnessing the Host Response to Leptosporisis for Diagnosis and Prognosis
openApr 30, 2028$70,200 - $70,200
Central Africa International Epidemiology databases to Evaluate AIDS
openApr 30, 2026$227,788 - $227,788
Targeting TB transmission hotspots to find undiagnosed TB in South Africa: a genomic, geospatial and modeling study (TARGET- TB)
openApr 30, 2027$314,460 - $314,460
Caribbean, Central, and South America network for HIV Epidemiology (CCASAnet)
openApr 30, 2027$220,447 - $220,447
Adaptive Immune Responses to Congenital and Postnatal Cytomegalovirus Infection
openApr 30, 2029$598,664 - $598,664
The Molecular Basis of Staphylococcus aureus SplB manipulation of the host
openApr 30, 2030$390,000 - $390,000
Metabolic determinants of Mtb virulence, vulnerability and variation
openApr 30, 2027$311,641 - $311,641
Virulence and Adaptation to the Host Environment of Pathogenic Leptospira
openApr 30, 2028$352,728 - $352,728
Interrogating the RIP kinase function of LRRK2 in chronic inflammation and susceptibility to infection.
openApr 30, 2027$162,000 - $162,000
Host-Pathogen Interaction in Leptospirosis
openApr 30, 2028$78,022 - $78,022
Identifying correlates of risk for future tuberculosis disease progression in children (INTREPID)
openApr 30, 2028$28,397 - $28,397
Circularization of RNA to improve the durability of the vaccine immune response
openApr 30, 2030$798,400 - $798,400
EGF as an environmental cue of B. burgdorferi gene regulation
openApr 30, 2027$162,000 - $162,000
Investigating the chromatin remodeling functions of polyphosphate condensates in Pseudomonas aeruginosa
openApr 30, 2030$779,915 - $779,915
Increasing the protective capacity of antibodies by enhancing Fc-mediated responses
openApr 30, 2030$416,276 - $416,276
Role of ASIC1a activation in ECM associated brain injury and mortality
openApr 30, 2027$213,000 - $213,000
Immune signatures of CMV disease risk after orthotopic liver transplant
openApr 30, 2030$832,910 - $832,910
Autologous Non-viral CRISPR/Cas Homology-directed Repair for Artemis-deficient Severe Combined Immunodeficiency
openApr 30, 2030$200,016 - $200,016
Phosphatases in lupus
openApr 30, 2030$558,045 - $558,045
Determining Optimal Immunosuppression and Kidney Allocation Strategies for Mitigating Risks from Epstein-Barr Virus in Kidney Transplant Centers
openApr 30, 2030$644,770 - $644,770
Orchestration of the antibody response by PI3K-gamma
openApr 30, 2030$837,497 - $837,497
A global Infectious diseases framework to grow interdisciplinary research
openApr 30, 2030$146,170 - $146,170
Unraveling skin microbiota-immune interactions that drive early life commensal tolerance
openNov 6, 2026$47,767 - $47,767
Developing allogeneic iNKT cell adoptive therapy to improve outcomes for HSCT indications
openApr 30, 2027$306,500 - $306,500
Activation of type I interferon production in human immune cells by cell-to-cell transmission of HIV-1
openApr 30, 2028$479,925 - $479,925
Interpretable and Adaptable Graph Neural Networks: Modeling Metapopulation Dynamics of Vaccine-Preventable Childhood Infections
openApr 30, 2030$711,555 - $711,555
Transcriptional Regulation of human natural killer cell function
openApr 30, 2030$666,567 - $666,567
Accelerating Public Health Impact Through the University of Washington/NASTAD Research Alliance in Implementation Science to End HIV (RAISE) Regional Consultative Hub
openApr 30, 2030$623,243 - $623,243
Exploratory study of pesticide use and coccidioidomycosis
openApr 30, 2027$247,621 - $247,621
Structural interrogation of the HIV-1 virion and the mechanism of the capsid targeting compound Lenacapavir
openApr 30, 2026$653,693 - $653,693
Modulation of Pediatric Sepsis by Virus Persistence
openApr 30, 2030$721,728 - $721,728
Immune repertoire remodeling following B cell-targeted CAR T cells for induction of renal allograft tolerance in non-human primates
openApr 30, 2030$1,648,086 - $1,648,086
Engineering non-replicating self-recirculating phages as platform for gene therapy of the microbiome
openApr 30, 2027$233,250 - $233,250
A Novel Broad-Spectrum Nanoimmunotherapeutic Approach for Combating Multidrug Resistant Bacteria
openApr 30, 2030$392,634 - $392,634
Carbohydrate based multi-component vaccine against Bordetella pertussis
openApr 30, 2030$780,834 - $780,834
Influence of Maternal IgA on Neonatal iNKT Cell Development and Gluten Sensitive Enteropathy.
openMay 14, 2028$41,778 - $41,778
Functional Omics Core Laboratory
openMay 14, 2026$2,065,495 - $2,065,495
Control of Long-lived HIV Cellular Reservoirs in memory CD4+ T cells by Bach2
openApr 30, 2027$499,550 - $499,550
Identifying Mechanisms of Resistance to Pathogen-Specific Antibacterial Antisense Compounds and Strategies to Circumvent Them
openApr 30, 2027$254,478 - $254,478
Lead optimization of oral DHFR inhibitor for the treatment of multidrug-resistant N. gonorrhoeae infections.
openApr 30, 2028$1,000,000 - $1,000,000
Ubiquitin pathway modulators as novel antituberculosis drugs
openApr 30, 2027$302,421 - $302,421
Dysregulation of Gamma Secretase in Common Acquired Hidradenitis Suppurativa
openMay 14, 2028$54,538 - $54,538
Metabolic determinants of carbon dioxide tolerance in the pathogenic fungi, Cryptococcus neoformans
openApr 30, 2027$158,433 - $158,433
Esx5 secretome in TB and TB-HIV pathogenesis and immunity
openApr 30, 2030$820,246 - $820,246
Advanced development of multi-omics based assays to predict late radiation organinjuries - the DEARE-Watch project
openApr 30, 2030$570,849 - $570,849
Robust verification of genetic variant-associated candidate off-target sites
openApr 30, 2028$856,513 - $856,513
Validated Immunoassays to Accelerate Therapeutic Genome Editing INDs
openApr 30, 2028$715,222 - $715,222
Leveraging antibody-omics to prevent and detect TB in children affected by HIV
openApr 30, 2027$209,750 - $209,750
Development of immune evasive strategies for allogeneic cell replacement therapies
openApr 30, 2026$307,091 - $307,091
Clonal lineage tracing of HIV specific NK memory cells
openApr 30, 2027$220,000 - $220,000
Understanding formation and dynamics of the SIV reservoir.
openApr 30, 2027$824,331 - $824,331
Machine Learning to Modulate Influenza Immunity
openApr 30, 2030$1,195,056 - $1,195,056
Multimodal Nanoparticles for Severe Inflammation and Sepsis
openApr 30, 2030$684,206 - $684,206
Clinical Pharmacology Quality Assurance (CPQA)
openMay 29, 2026$1,836,411 - $1,836,411
Exploring innate immune responses to rhinovirus in allergic asthma
openApr 30, 2027$80,750 - $80,750
Identification and targeting of metabolic profiles in cytotoxic T-lymphocyte (CTL)-resistant, HIV-infected CD4+ T-cells
openMay 27, 2028$49,538 - $49,538
Rapid Stress Response in Bacterial Pathogens: the Role of Extant Porins in Antibiotic Tolerance
openApr 30, 2030$637,275 - $637,275
DEVELOPMENT OF MONOCLONAL ANTIBODIES TO CHEMOKINES IN THE FERRET MODEL OF RESPIRATORY DISEASE.
openMay 31, 2027$599,987 - $599,987
Enhancing the utility of deer mice as an infectious disease model
openMay 31, 2030$466,725 - $466,725
Understanding the role of ubiquitination-like processes in bacterial antiviral immunity
openOct 31, 2027$42,843 - $42,843
Respiratory pathogen-specific T cell signatures following vaccination, natural infection, and treatment
openMay 31, 2027$93,590 - $93,590
An integrated approach to understand and diagnose congenital Chagas disease
openMay 31, 2027$119,448 - $119,448
Home Fingerprick Blood-Based HIV Self-Test For Quantitative Monitoring Of Viral Rebound
openAug 31, 2026$554,633 - $554,633
Focal mass drug administration (fMDA) to reduce Plasmodium vivax transmission, a pragmatic cluster randomized controlled trial in Peru
openMay 31, 2027$668,530 - $668,530
Understanding HIV's impact on RR/MDR-TB development and transmission through genomics
openMay 31, 2026$20,698 - $20,698
Linking Mycobacterium Tuberculosis infection outcomes with transcriptional networks in genetically diverse mouse macrophages
openMay 31, 2028$35,130 - $35,130
Separating the molecular determinants that govern the evolution of Orthoflavivirus NS5-mediated IFN antagonism
openMay 31, 2028$49,538 - $49,538
A more durable and universal adjuvanted influenza vaccine through synthetic biology
openMay 31, 2027$599,526 - $599,526
ANTIBODY REAGENTS FOR IMMUNOLOGIC ANALYSIS OF UNDER-REPRESENTED MAMMALIAN MODELS
openMay 31, 2028$1,500,000 - $1,500,000
Sustained Release of Potent Antiviral Prodrugs for HIV Prevention
openMay 31, 2026$67,212 - $67,212
M. tuberculosis exosome detection for pediatric TB diagnosis
openMay 31, 2027$104,166 - $104,166
DON in Pediatric Cerebral Malaria: A Phase I / II Dose-Escalation Safety Study
openMay 31, 2027$548,344 - $548,344
Cellular Immunology Core Laboratory
openMay 31, 2026$2,573,880 - $2,573,880
Morphological and molecular identification of Hyalomma tick vectors of Crimean-Congo Hemorrhagic Fever virus
openMay 31, 2028$355,000 - $355,000
Clinical Impact of the Cefazolin Inoculum Effect
openMay 31, 2028$161,779 - $161,779
Genetics & Clinical Cohorts
openMay 31, 2026$155,060 - $155,060
Diagnostic Innovations for Pediatric Tuberculosis in Bolivia
openMay 31, 2028$120,406 - $120,406
Host and parasite factors influencing P. vivax RBC invasion and asexual development
openMay 31, 2027$154,170 - $154,170
Malaria associated pathogenesis of chronic kidney disease (MAP-CKD)
openMay 31, 2027$263,811 - $263,811
Lung Transplant Clinical Trial Network (LT-CTN)
openMay 31, 2028$297,730 - $297,730
Chromatin Biology of the African Trypanosome
openMay 31, 2027$1,057,830 - $1,057,830
Understanding the Molecular Rules of a Bacterial Multidrug Efflux Transporter
openMay 31, 2027$36,868 - $36,868
Biochemical Mechanism of HIV DNA Integration
openMay 31, 2030$819,601 - $819,601
Defining Mechanisms for Plasmacytoid Dendritic Cell-driven Mycobacterium tuberculosis Susceptibility
openMay 31, 2027$162,000 - $162,000
Safety and Tolerability of TASIS-Peanut (Targeted Allergen Specific Immunotherapy within the Skin) patch for the Treatment of Peanut Allergy
openMay 31, 2028$999,658 - $999,658
Host Pathogen Variation & TB Pathogenesis
openMay 31, 2026$210,900 - $210,900
Effectively Linking Molecular Informatics and Network Analytics to Reduce Malaria (ELIMINAR-Malaria)
openMay 31, 2028$22,000 - $22,000
East Africa International Epidemiology Database to evaluate AIDS (IeDEA) Regional Consortium
openMay 31, 2026$195,343 - $195,343
Novel strategies for treatment of Mycobacterium abscessus pulmonary disease
openMay 31, 2026$240,878 - $240,878
Vaccine- and infection-derived correlates of protection for cholera
openMay 31, 2029$236,187 - $236,187
Reducing malaria in pregnancy through focal drug administration in household members: A pilot feasibility trial
openMay 31, 2026$123,118 - $123,118
Early Life B-cell and plasma cell development in the human Spleen: a new paradigm for lifelong immunity
openMay 31, 2030$778,829 - $778,829
Unraveling the spectrum of intrabacterial amide hydrolysis to develop new classes of pyrazinoic acid prodrugs against pyrazinamide resistant Mycobacterium tuberculosis
openMay 31, 2030$813,373 - $813,373
Dissecting the role of CD38 and metabolism in the heightened Treg potential of human neonatal naïve CD4+ T cells
openJun 2, 2027$47,767 - $47,767
IL-15 Therapy Combined with TGF-Beta Blockade for Sustained HIV Remission
openMay 31, 2030$800,389 - $800,389
Developing Novel Tools for Precision Targeting of Pro-Autoimmune Th17 Cells
openMay 31, 2027$166,000 - $166,000
Planning for Na-GST-1 Hookworm Vaccine Phase 2 CHIM Efficacy Trial
openMay 31, 2026$242,058 - $242,058
Dissecting the molecular targets to overcome beta-lactam resistance in M. abscessus complex
openMay 31, 2030$901,706 - $901,706
Uncovering mechanisms of nitric oxide detoxification and reactivity in Pseudomonas aeruginosa
openMay 31, 2027$158,000 - $158,000
A Novel Cost-Effective Multispecific Therapeutic for Dengue
openMay 31, 2026$294,583 - $294,583
An unconventional regimen comprising biofilm disruptor as an adjunct with antibiotics to treat Mycobacterium abscessus chronic lung disease
openMay 31, 2027$155,227 - $155,227
Exploiting a high-precision phenotypic map to illuminate environmental sensing by a fungal meningitis pathogen
openMay 31, 2030$616,588 - $616,588
The Effects of Doxycycline on Inflammation and the Microbiome: 'Flipping the Script' on STI PEP
openMay 31, 2030$797,734 - $797,734
Human antibodies as broad alphavirus immunotherapeutics
openMay 31, 2030$843,620 - $843,620
Development of Conformer-Specific Anti-I-A Class II mAbs
openMay 31, 2027$164,000 - $164,000
Solving the puzzle of beta-1,6-glucan in the cryptococcal cell wall
openMay 31, 2030$773,053 - $773,053
Host Regulation of Flavivirus Infection
openMay 31, 2030$530,385 - $530,385
Phage-Polymer Nanoparticles for Treatment of Antibiotic-Recalcitrant Wound Biofilm Infections
openMay 31, 2030$593,860 - $593,860
STING induced IFNL2/3 protects human intestinal epithelial cells from rotavirus infection
openMay 31, 2030$502,248 - $502,248
A multipronged, mRNA gene therapy approach to HIV cure
openMay 31, 2030$486,057 - $486,057
Systemic and gastrointestinal targeted CDPK1 inhibitors for cryptosporidiosis
openMay 31, 2030$812,603 - $812,603
Virus and Host Directed Immunotherapies for Cure in SHIV-infected Infant Macaques
openMay 31, 2030$1,332,155 - $1,332,155
Study the role of ICOS on murine and human ILC2s
openMay 31, 2030$590,711 - $590,711
Pre-clinical studies to repurpose FDA-approved adenosine A2A receptor antagonists for lethal rickettsial infection
openMay 31, 2030$463,698 - $463,698
Defining macrophage defense during Klebsiella pneumoniae bacteremia
openMay 31, 2027$249,000 - $249,000
Characterizing the Neonatal Nasal Microbiome Following a Parent-to-Child Nasal Microbiota Transplant
openMay 31, 2027$401,191 - $401,191
Investigating Lipid-gene Molecular Profiles of Septic ARDS
openMay 31, 2027$424,223 - $424,223
Functions of mRNPs in RNA metabolism in Plasmodium falciparum
openMay 31, 2030$375,000 - $375,000
DNA Binding Dynamics and Oligomerization of Sensors of the PYHIN family in Pattern Recognition
openMay 31, 2028$556,427 - $556,427
Novel B cell epitope discovery against human coronaviruses
openMay 31, 2030$899,935 - $899,935
Mycobacterium tuberculosis disease effect on HIV-1 immunity, evolution, and persistence
openMay 31, 2026$711,993 - $711,993
Injectable 3D-Clustered Human Fibroblastic Reticular Cells for Expanding Regulatory T Cells
openMay 31, 2027$231,131 - $231,131
Molecular Programs Governing Enterococcal Translocation
openMay 31, 2030$828,820 - $828,820
Decoding mechanisms of early life inflammation
openMay 31, 2030$797,735 - $797,735
Bridging cell and organism scales to model viral, cell, and microenvironmental determinants of infection outcome
openMay 31, 2030$812,397 - $812,397
Lymphatic control of germinal centers
openMay 31, 2030$806,693 - $806,693
The Role of Tbet+ B cells in viral reinfection
openMay 31, 2027$416,121 - $416,121
Testing the contribution of ex-Tregs to autoimmunity and cancer immunity
openMay 31, 2027$441,202 - $441,202
Self Assembled Peptide Nanoparticles as Multi-Antigen Universal Influenza Vaccines
openMay 31, 2030$390,942 - $390,942
Effects of Vaccination on Acute and Post-Acute Respiratory Viral Infection Outcomes in Solid Organ Transplant Recipients
openMay 31, 2030$1,442,898 - $1,442,898
Developing new antifungals against sterolglycosidases
openMay 31, 2030$782,178 - $782,178
Decoding the polymicrobial interactions in bile acid metabolism by the gut microbiome.
openJun 11, 2028$37,731 - $37,731
Cellular Identity of the Intact HIV Reservoir
openMay 31, 2027$489,500 - $489,500
Clinical Research Products Management Center (CRPMC)
openJun 15, 2026$8,628,931 - $8,628,931
Characterization of Allogeneic T Cells Mediating HIV Cure
openMay 31, 2030$1,657,972 - $1,657,972
Host-pathogen interactions during Staphylococcus aureus spine infections
openMay 31, 2030$208,332 - $208,332
Defining the Structure and Function of a New Family of Peptidoglycan Crosslinking Enzymes
openMay 31, 2030$661,693 - $661,693
A membrane fusion apparatus trailblazes measles virus spread in airway cells
openMay 31, 2027$427,625 - $427,625
Regulation of Chlamydial Divisome Assembly
openMay 31, 2030$782,795 - $782,795
A CRISPR based organoid screen for mediators of epithelial-myeloid interactions
openMay 31, 2027$453,750 - $453,750
Manipulation of antibody responses by a retrovirus
openMay 31, 2027$451,000 - $451,000
Novel Integrative Analysis of Microbiome and Host Genetics in Childhood Asthma Research
openMay 31, 2030$597,904 - $597,904
TGFβ Restricts Tfh2 Differentiation but Augments IgE-Mediated Mast Cell Function: Critical and Opposing Roles in Allergic Disease
openMay 31, 2027$162,000 - $162,000
Non-viral gene therapy with eCD4-Ig
openMay 31, 2026$917,294 - $917,294
Elucidating Novel Mechanism of HIV-1 Evading APOBEC3G Antiviral Function Through Selective Viral RNA Packaging
openMay 31, 2027$400,125 - $400,125
Johns Hopkins HIV Implementation Science Hub (Hopkins Hub)
openMay 31, 2030$773,365 - $773,365
Rapid Antigen Test for Diagnosis of Active HCV Infection
openMay 31, 2027$272,133 - $272,133
Adipocyte-Eosinophil Communication and Its Role in Regulation of Airway Function
openMay 31, 2030$730,392 - $730,392
Development of a Human Lymph node-on a Chip Microphysiological System for Evaluation of Vaccine Effectiveness against Infectious Diseases
openMay 31, 2027$437,477 - $437,477
Role of Merkel cell polyomavirus small T antigen in persistent infection
openMay 31, 2030$634,981 - $634,981
Autoimmunity, calorie restriction, and core body temperature
openMay 31, 2027$541,500 - $541,500
Cellular mechanisms of macrophage activation syndrome
openMay 31, 2030$188,772 - $188,772
Evaluating the safety, immunogenicity and efficacy of a robust attenuated Mtb vaccine in the setting of HIV co-infection
openMay 31, 2030$905,998 - $905,998
Role of HMGB1 in an experimental model of Bacterial ligand induced Vasculitis
openMay 31, 2027$459,250 - $459,250
Center for accelerated development of drug candidates targeting high threat bacterial infections
openMay 31, 2030$7,562,521 - $7,562,521
Dissecting the mechanism of altered immune responses during obesity
openMay 31, 2027$425,647 - $425,647
Deciphering innate and adaptive immune responses to Rickettsia parkeri
openMay 31, 2030$745,295 - $745,295
Fine-resolution genetic mapping of advanced intercross lines of Biomphalaria glabrata
openMay 31, 2027$430,251 - $430,251
Role of TXLNA in cytosolic DNA-mediated innate immunity
openMay 31, 2030$382,500 - $382,500
Synoviocyte endothelial cell cross talk in rheumatoid arthritis
openMay 31, 2027$459,250 - $459,250
Mechanistic Investigation of a Rotavirus Auxiliary Protein NSP6 Countering Host Defense
openMay 31, 2030$593,021 - $593,021
The anatomy of T-cell mediated neutrophil recruitment during lung infection
openMay 31, 2027$472,210 - $472,210
IND-enabling development of MM-009, a reservoir-intravaginal ring for ultra-highrates of month-long lactic acid release to treat and prevent bacterial vaginosis
openMay 31, 2028$1,025,000 - $1,025,000
Therapeutic Mechanisms of Farnesol in Modulating Gut Dysbiosis and Neuroinflammation in Multiple Sclerosis
openMay 31, 2028$418,493 - $418,493
Evaluating the impact of pre-existing humoral immunity on hepatocyte death
openMay 31, 2027$516,175 - $516,175
Advancing mosquito blood-feeding rate quantification using micro-CT imaging: an innovative tool for vector-borne disease transmission studies
openMay 31, 2027$135,107 - $135,107
Buy the world a coke and keep it mosquito free
openMay 31, 2027$433,303 - $433,303
Isothermal DNA amplification using double DNA primer
openMay 31, 2027$151,496 - $151,496
NIAID VIROLOGY QUALITY ASSURANCE (VQA)
openJun 20, 2026$3,434,765 - $3,434,765
Lytic viral genes in the pathogenesis of oncogenic gammaherpesviruses
openMay 31, 2027$420,335 - $420,335
A less resource-intensive mouse model of M. abscessus lung disease
openMay 31, 2027$426,938 - $426,938
Predicting Viral Spillover Risk using Machine Learning and Adversarial Mutation
openMay 31, 2027$422,814 - $422,814
A chromatin structure informed exploration of gene regulation in Anopheles coluzzii
openMay 31, 2027$429,000 - $429,000
Biomaterial technologies to train innate immunity
openMay 31, 2027$425,226 - $425,226
Identifying the Determinants of Persister Cell Survival in M. tuberculosis.
openMay 31, 2027$404,108 - $404,108
Mingling life imaging and cell subpopulations expression analysis in NHP lungs targeted with exosome associated double AAV vectors
openMay 31, 2027$437,250 - $437,250
Understanding heterogeneity of necroptotic cell death and mechanism(s) of necroptosis escape
openMay 31, 2027$450,764 - $450,764
Development of novel antibodies to autoreactive B cells as a potential therapeutic for SLE patients
openMay 31, 2027$423,500 - $423,500
Revealing the Role of Lipid-Laden Macrophages in Staphylococcus aureus Osteomyelitis Abscess Formation
openJun 30, 2027$34,880 - $34,880
Genetic basis of incomplete penetrance of RPSA haploinsufficiency for congenital asplenia
openJun 30, 2027$466,125 - $466,125
The role of VacA in Helicobacter pylori-host cell cholesterol homeostasis
openJun 30, 2028$49,538 - $49,538
The Role of Xist in T Cell Activation and Female-Biased Autoimmunity
openJun 30, 2027$46,207 - $46,207
Alphavirus determinants of microvascular endothelial cell infection
openJun 30, 2027$254,250 - $254,250
Immunometabolite L-2-Hydroxyglutarate in Natural Killer Cell Antiviral Immunity
openJun 30, 2029$54,538 - $54,538
Structural Basis for HIV-1 Rev Nucleocytoplasmic Trafficking
openJun 30, 2028$43,193 - $43,193
Novel TNF Secretion Assays
openJun 30, 2027$149,041 - $149,041
Type 2 Immune Responses in Endotoxemia-induced Lung Injury
openJun 30, 2027$486,109 - $486,109
Systematic identification of interactions between Lyme Borrelia and Ixodes scapularis
openJun 30, 2027$461,375 - $461,375
Macrophage-derived nanoparticles as an adjuvant therapy for severe bacterial pneumonia
openJun 30, 2029$43,049 - $43,049
Chemical Probes of Complement Pathways
openJun 30, 2027$407,156 - $407,156
High throughput identification of bacteriophages and their hosts with single-cell transcriptomics
openDec 31, 2027$36,046 - $36,046
Innate immune regulation of mAb-induced infusion reactions
openJun 30, 2027$431,147 - $431,147
Norepinephrine-mediated resistance to nutritional immunity in Neisseria gonorrhoeae
openJun 30, 2029$38,945 - $38,945
Elucidating the role of fimbriae in Klebsiella pneumoniae-mediated liver abscess formation
openJun 30, 2027$427,625 - $427,625
Novel Antivirals Targeting Lenacapavir-Resistant HIV
openJun 30, 2029$49,538 - $49,538
RANKL regulation of human B cell responses
openJun 30, 2026$88,360 - $88,360
Novel Mechanisms of CD4-Independent Immunity Against Pneumocystis
openJun 30, 2027$226,500 - $226,500
Age-associated changes in B cell and antibody effector responses to Streptococcus pneumoniae
openJun 30, 2028$49,538 - $49,538
The Cell Biology of HIV-1 Genome Trafficking
openJun 30, 2030$376,863 - $376,863
Extent, dynamics and mechanisms of Plasmodium vivax immune evasion caused by PvDBP gene amplification
openJun 30, 2028$63,525 - $63,525
Once Bitten: Acquisition of Malaria Adaptive Immunity (OBAMA - Immunity)
openJun 30, 2028$154,153 - $154,153
Integrating single-cell omics and ancestry-adjusted eQTL mapping to characterize Tuberculosis immune response
openJun 30, 2026$43,200 - $43,200
Control of CD8+ T cell Memory Homeostasis via Extracellular Damage Sensors ARTC2 & P2RX7
openJun 30, 2026$90,964 - $90,964
Sustained release of VRC07 from capsule-intravaginal ring for preventing HIV transmission
openJun 30, 2026$306,183 - $306,183
Targeted antibiotic therapy for Shigella among children in low-resource settings
openJun 30, 2029$140,429 - $140,429
Liposomal Amphotericin B and Flucytosine Antifungal Strategies for Talaromycosis (LAmB-FAST)
openJun 30, 2031$531,188 - $531,188
The effect of HIV on SARS-CoV-2 transmission and emergence of variants of concern
openJun 30, 2026$201,406 - $201,406
Characterization of cAMP signaling microdomains in the human pathogen Trypanosoma cruzi
openJun 30, 2027$444,688 - $444,688
Contribution of C4b-binding protein to interactions of Neisseria gonorrhoeae with human neutrophils
openJun 30, 2028$38,922 - $38,922
Evaluation of High-throughput Extracellular Vesicle Loading Platform for Therapeutic Genome Editing INDs
openMay 1, 2028$452,378 - $452,378
Innovative Antibiotic Combinations for Hypervirulent Klebsiella pneumoniae
openJun 30, 2027$456,911 - $456,911
Type 5 secretion as a novel mechanism to deliver protein effectors directly into mammalian host cells
openJun 30, 2027$410,497 - $410,497
Innate memory signaling in airway epithelial cells
openJun 30, 2027$235,500 - $235,500
Structural and Biochemical Studies of HIV and MMTV Retroviral Integration onto Nucleosome-bound Target DNA
openJun 30, 2028$47,475 - $47,475
Enhancing Surveillance Methods for Genomic Epidemiology in Healthcare
openJun 30, 2030$128,655 - $128,655
Basic immunological toolbox for genus Peromsycus, infection tolerant reservoirs of zoonotic agents
openJun 30, 2027$431,750 - $431,750
Gamma herpesvirus impact on required B cell:CD4 T interactions in a B cell-dependent, antibody-independent mouse model of multiple sclerosis
openJun 30, 2027$427,627 - $427,627
Development of an improved transposon mutagenesis system for comprehensive genetic analysis of Borrelia burgdorferi
openJun 30, 2027$165,000 - $165,000
Innate Cells with Adaptive Specificity: Bond Kinetics of NK Cell Inhibitory Receptor Ly49C
openJun 30, 2028$78,040 - $78,040
Characterization of Plasmodium falciparum long non-coding RNAs and their roles in gene regulation
openJun 30, 2027$445,488 - $445,488
The evolutionary genetic basis for changes in viral receptor-binding specificities
openJun 30, 2028$41,963 - $41,963
Modulation of cytomegalovirus replication by the viral temperance factor RL13
openJun 30, 2027$426,939 - $426,939
PET to Assess Post-TB Lung Disease in TB Patients with / without HIV coinfection
openJun 30, 2027$445,500 - $445,500
Mechanisms of sigma-factor-dependent transcriptional control in Mycobacterium tuberculosis
openJun 30, 2028$75,520 - $75,520
Bacterial and Host Heterogeneity in TB latency, persistence and progression
openJun 30, 2026$38,013 - $38,013
Enhancing immunity to malaria in young children with effective chemoprevention
openJun 30, 2027$513,257 - $513,257
MEPCS (Multi-epitope protease cleavage sites) vaccine for protecting against SIV rectal transmission
openJun 30, 2029$657,563 - $657,563
A Structural and Functional Interrogation of the Ligand-Independent Signaling Properties of the IgE BCR
openJun 30, 2028$49,538 - $49,538
Innovative Tools to Expand HIV Self-Testing and Long-Acting Injectables for HIV Treatment and Prevention Among Commercial Minibus Drivers (I-TEST LAIs)
openJun 30, 2029$93,646 - $93,646
Contribution of RpoS to persistence of Borrelia burgdorferi in mammals
openJun 30, 2027$457,875 - $457,875
The role of the spleen in maintaining immune tolerance to transplanted islets
openJun 30, 2027$423,500 - $423,500
Alveolus on a chip model of non-tuberculous mycobacteria infection
openJun 30, 2027$451,000 - $451,000
Development of Diagnostic Antibodies for Acute and Chronic Chagas Disease
openJun 30, 2027$449,408 - $449,408
A 3-In-One Design of CAR Tregs for Robust Immunotolerance
openJun 30, 2027$423,500 - $423,500
Molecular Tailoring of Bispecific Antibody–BottlebrushConjugates
openJun 30, 2027$386,194 - $386,194
Virus-host interactions regulating innate signaling for human cytomegalovirus latency
openJan 31, 2027$384,698 - $384,698
Dynamic and functional analysis of Enterococcus faecalis penicillin binding protein 4 pedestal domain
openJun 30, 2030$51,628 - $51,628
A new deep learning approach to probe the molecular basis of inhalation allergens
openJun 30, 2027$440,000 - $440,000
Myobacterium tuberculosis Phenylalanine Synthesis as a Novel Drug Target
openJun 30, 2027$423,500 - $423,500
Identification of Cross-Protective Surface Antigens in Burkholderia Species
openJun 30, 2027$38,936 - $38,936
Role of Carbon Metabolism and Virulence of Shigella flexneri
openJun 30, 2030$391,709 - $391,709
Development of novel model to measure TCR signal strength in dual TCR cells
openJun 30, 2027$159,500 - $159,500
Antibody feedback on B cell response to vaccination
openJun 30, 2029$36,673 - $36,673
Microbiology of Post-Treatment Lyme Disease Syndrome
openJun 30, 2029$495,862 - $495,862
Mechanisms of varied sensitivity of P. falciparum field isolates to the antimalarial drug pipeline
openJun 30, 2028$97,524 - $97,524
Inflammation and Fibrosis in Pulmonary TB: the INFIN-TB Study
openJun 30, 2027$335,986 - $335,986
Harnessing the Malarial Immunity Omics Landscape in Vaccinated and Unvaccinated Children for Improved Therapeutic Strategies
openJun 30, 2029$232,955 - $232,955
Development of mosaic enterovirus mRNA vaccine to prevent hand, foot and mouth disease
openJun 30, 2027$433,175 - $433,175
Structural Studies of Helicobacter Pyloris Cag Type IV Secretion System
openJun 30, 2028$80,224 - $80,224
Investigation of the role(s) chlamydial polymorphic membrane proteins (Pmps) play during infection with C. trachomatis
openJun 30, 2027$423,500 - $423,500
Introducing a novel computational framework for B-cell epitope prediction based on immune-induced selection signatures
openJun 30, 2027$406,260 - $406,260
Cell-type-specific Evaluation of Liver Allografts during Normothermic-Machine-Perfusion
openJun 30, 2027$429,000 - $429,000
Investigating a hemagglutinin mediated molecular mechanism of avian influenza A virus host tropism
openJun 30, 2027$49,538 - $49,538
Architecture of a divergent bipartite internal ribosome entry site from Giardiavirus
openJun 30, 2027$518,400 - $518,400
Use of random barcode transposon site sequencing as a tool for identifying nutrient acquisition strategies utilized by Mycobacterium tuberculosis during infection of human macrophages
openJun 30, 2027$227,096 - $227,096
The role of Salmonella Typhi virulence factors in systemic dissemination
openJun 30, 2029$42,895 - $42,895
Investigating the role of type 1 interferon signaling on vaccine stability within lymphatic endothelial cells
openJun 30, 2027$38,558 - $38,558
Defining mechanistic drivers of impaired B cell response to influenza A virus vaccine under conditions of obesity
openJun 30, 2027$75,052 - $75,052
Mechanical deformation of the cell envelope as a form of surface-sensing in Pseudomonas aeruginosa
openJun 30, 2028$80,020 - $80,020
Immunomodulatory effects of interferon lambda on infant neutrophils
openJun 30, 2027$416,199 - $416,199
Advancing Transplantation Outcomes in Children
openJun 30, 2028$66,028 - $66,028
Deciphering the impact of sex in early subtype C HIV infection and during HART
openJun 30, 2027$63,564 - $63,564
Inhibition of lipoprotein synthesis in Helicobacter pylori
openJun 30, 2027$481,250 - $481,250
Leptospira prevalence, cycling, and infection in the peridomestic environment
openJun 30, 2028$146,890 - $146,890
Isolation of broadly protective monoclonal antibodies for Crimean Congo Hemorrhagic Fever
openJun 30, 2029$58,536 - $58,536
Uncovering the mechanisms and implications of BST2 antagonism by SARS-CoV-2
openJun 30, 2028$49,538 - $49,538
Assessment of Biomarker Guided CNI Substitution in Kidney Transplantation
openJun 30, 2029$50,000 - $50,000
Characterization of a ubiquitin binding domain in interferon pathway protein RIOK3
openJun 30, 2027$143,094 - $143,094
Characterizing the Renal Immune Microenvironment in Antibody-Mediated Rejection to Predict Treatment Response using Imaging Mass Cytometry
openJun 30, 2026$76,756 - $76,756
Bacterial and host determinants of progression, manifestations and consequences of TB
openJun 30, 2026$8,125 - $8,125
A Randomized Clinical Trial to Evaluate Solutions for the Management of Virologic Failure for Individuals on TLD in Sub-Saharan Africa
openJun 30, 2027$278,479 - $278,479
Innovative approaches to enhance regulatory immune cell function and renal transplant survival in nonhuman primates
openMay 31, 2030$1,455,073 - $1,455,073
Adaptive immune responses in bats
openJun 30, 2030$452,475 - $452,475
Effects of a chromosomal inversion on gene regulation in a major malaria vector
openJun 30, 2029$51,628 - $51,628
Evaluation of Immunodominant fragments of PfGARP for malaria vaccine development
openJun 30, 2027$412,500 - $412,500
Tobacco Mosaic Virus as a mucosal delivery platform for an intranasal vaccine against Pseudomonas aeruginosa
openJun 30, 2027$261,846 - $261,846
Gene regulatory network of memory B cell and long-lived plasma cell differentiation
openJun 30, 2030$625,348 - $625,348
Zoonotic Uropathogenic Escherichia coli in Northwest Ecuador: Incidence and Risk Factors
openJun 30, 2027$158,314 - $158,314
PB1-F2 mediates hypoxemia in influenza
openJun 30, 2027$433,125 - $433,125
Determining function and mechanism of lncRNA Chast in Trypanosoma cruzi infection and dissemination
openJun 30, 2027$440,000 - $440,000
Molecular mechanisms of signal transduction by the Campylobacter jejuni BumSR two-component system
openJun 30, 2027$451,000 - $451,000
Defining correlates of protection from dengue illness in a long-term cohort study of multigenerational house-holds in Thailand
openJun 30, 2028$94,253 - $94,253
3STEP: A swab-seal-read assay for tuberculosis and RIF resistance enabled by autonomous extraction technology
openJun 30, 2027$1,000,000 - $1,000,000
Elucidating astrovirus egress and the effects of infection on gut homeostasis
openSep 30, 2027$42,788 - $42,788
The role of pH in the pathogenesis of type 1 diabetes
openJun 30, 2027$429,000 - $429,000
Exploiting a multiplex HTS assay to identify novel boron-based inhibitors of mycobacterial class II aminoacyl-tRNA synthetases
openJun 30, 2027$415,978 - $415,978
MSP68 as an effective radiation countermeasure
openJun 30, 2027$167,500 - $167,500
HIV-1 Fusion on Native Membranes Captured by Cryo-Electron Tomography
openJun 30, 2030$603,338 - $603,338
FOXN1 variant regulation of T cell production
openJun 30, 2027$436,466 - $436,466
Genetic Regulation of Factor VIII Inhibitor Development
openJun 30, 2027$470,553 - $470,553
Bringing alloreactivity into focus with the lens of TCR cross-reactivity
openJun 30, 2027$459,439 - $459,439
In vivo and ex vivo gene editing for Artemis-deficient SCID
openJun 30, 2027$420,771 - $420,771
From inhibitors to enzymatic deficiencies: exploring alterations in erythrocyte glycolysis as an antimalarial strategy.
openJun 30, 2030$187,056 - $187,056
Designing better T cell epitopes for improved T cell vaccines and therapies
openJun 30, 2027$462,000 - $462,000
Control of regulatory T cell fitness and function by heme synthesis
openJun 30, 2030$647,187 - $647,187
New potent orally bioavailable nitro-containing compounds to treat mycobacterial infections
openJun 30, 2028$2,248,740 - $2,248,740
Individualized HIV Curative Combination Strategy against Persistent HIV on ART
openMay 31, 2030$3,568,644 - $3,568,644
IAS 2025. the 13th IAS Conference on HIV Science, Kigali, Rwanda, 14-17 July 2025
openJun 30, 2026$940,000 - $940,000
The Role of Ariadne RBR E3 ubiquitin protein ligase 2 (ARIH2) in influenza A virus replication and pathogenesis in the airway epithelial cells
openJun 30, 2030$605,778 - $605,778
Regulation of neutrophil plasticity, heterogenicity, and functional ambivalency by WNT5 in colitis
openJun 30, 2029$2,685,326 - $2,685,326
Regulation of the cGAS-STING pathway by RNF11
openJun 30, 2027$425,004 - $425,004
Investigating the role of T cells in promoting post-acute memory deficits after COVID-19 in mice
openJun 30, 2027$107,995 - $107,995
Bacterial cell wall remodeling, innate immunity, and pathogenesis
openJun 30, 2029$2,841,668 - $2,841,668
Sequence specific determinants, and impacts, of NS2 interactions with the influenza A virus polymerase
openJun 30, 2027$438,500 - $438,500
Mechanisms that underpin immunoglobulin gene rearrangement
openJun 30, 2027$438,500 - $438,500
Sex differences in a cytokine controlling antibody class switch recombination
openJul 7, 2027$439,088 - $439,088
Metabolic targeting of CD4 T cells in CNS autoimmunity
openJun 30, 2030$790,222 - $790,222
B cell receptor dependent infection as a mechanism of immune-mediated enhancement of dengue virus infection and pathogenesis
openJun 30, 2030$649,530 - $649,530
Contributions of BRWD1-mediated cohesin conversion to B cell biology
openJun 30, 2029$3,018,216 - $3,018,216
Human cutaneous responses to arthropod-mediated viral transmission
openJul 7, 2027$449,625 - $449,625
A Unique Device to Measure Radiation Dose and Homogeneity of Exposure Following a Large-Scale Ionizing Radiation Event
openMay 31, 2030$350,000 - $350,000
The multifaceted roles of PI(4,5)P2 on HIV-1 assembly
openJun 30, 2027$132,300 - $132,300
Formation of a Novel SARS-CoV-2 Nucleocapsid Dimer: Impacts on Viral and Cellular Processes
openJun 30, 2027$438,983 - $438,983
Phage-Seq phenotyping of the Pseudomonas aeruginosa surface-ome
openJun 30, 2027$453,629 - $453,629
Microbiota-mediated colonization resistance to Acinetobacter baumannii.
openJun 30, 2030$582,350 - $582,350
Role of cholinergic neuroimmune signaling pathway disruption in the pathogenesis of Hirschsprung-associated enterocolitis
openJul 7, 2027$439,216 - $439,216
Develop novel iNOS/NO inhibitors for mitigating inflammatory cell death, ARDS, and MODS
openJun 30, 2027$385,625 - $385,625
Kinase activity rewiring in T cell trans-differentiation
openJun 30, 2027$464,750 - $464,750
Study the Treg-IL-27 axis in immune regulation
openJun 30, 2029$3,022,197 - $3,022,197
Bioinspired Point of Care Testing for HIV/HBV Co-infection
openJun 30, 2030$354,570 - $354,570
Understanding the influence of climate and other environmental factors on blastomycosis incidence and seasonality in northern Great Lakes states
openJun 30, 2027$419,274 - $419,274
Long-lived highly differentiated monocyte-derived cells (LDMs) activate lung-resident CD8+ T cell memory
openJun 30, 2027$415,250 - $415,250
Role of post-sepsis exercise therapy in regulating CD4 T cell immunity against secondary Pseudomonas aeruginosa infection
openJun 30, 2027$460,625 - $460,625
Development of siRNA-peptide libraries for delivery screening
openJun 30, 2027$506,000 - $506,000
Cellular Determinants of HCMV infection
openJun 30, 2030$525,095 - $525,095
Determinants of pegivirus persistence and immune control
openJun 30, 2030$692,689 - $692,689
A synthetic miR-7702: a potential therapeutic approach for SARS-CoV-2 infection
openJun 30, 2027$411,400 - $411,400
Uncovering the role of BND2 cells in autoimmunity
openJun 30, 2030$634,984 - $634,984
Single-cell phenotyping for better drug discovery
openJun 30, 2027$461,250 - $461,250
EV-D68 genetic neuropathogenesis determinants
openJun 30, 2027$430,170 - $430,170
The role of cryptic influenza virus proteins in replication and pathogenesis
openJun 30, 2029$3,085,097 - $3,085,097
Defining the impact of type 1 cytokine signaling on STAT-mediated epithelial reprogramming and barrier dysfunction in eosinophilic esophagitis
openJun 30, 2029$3,375,359 - $3,375,359
Natural Killer Cell Recruitment and Differentiation
openJun 30, 2027$223,068 - $223,068
How SAMHD1 regulates HIV-1 innate immunity and viral gene expression
openJun 30, 2030$769,414 - $769,414
Training of Neutrophils to Defend Against a Lethal Bacterial Infection of the Lung
openJun 30, 2027$430,760 - $430,760
Gardnerella promotion of N. gonorrhoeae pathogenesis
openJun 30, 2027$243,750 - $243,750
Notch regulation of airway epithelial-immune cell cross-talk in SARS-CoV-2 infection
openJun 30, 2027$448,688 - $448,688
Development of new tools to study how T. gondii rhoptry effector proteins are delivered into host cells during invasion
openJun 30, 2027$408,865 - $408,865
Overcoming obstacles in structural elucidation of B cell antigen receptor assembly and lateral interaction
openJun 30, 2027$489,500 - $489,500
Cell intrinsic antiviral immunity in diverse bats
openJun 30, 2030$454,726 - $454,726
Identifying novel immune determinants that influence S. aureus biofilm infection using Collaborative Cross (CC) mouse lines
openJun 30, 2027$417,845 - $417,845
Mechanisms of antagonism of BST2 isoforms and implications for HIV pathogenesis
openJun 30, 2030$368,750 - $368,750
Metabolic Regulation by SAPS3 of Virus-specific T cell Immunity
openJun 30, 2029$2,832,747 - $2,832,747
Harnessing phage resistance mechanisms for optimization of antibiotic therapy in mycobacteria
openJun 30, 2027$408,375 - $408,375
Characterization of Homotypic Fusion in Chlamydia muridarum
openJun 30, 2027$156,000 - $156,000
Hyaluronidase mediated GBS Disease
openJun 30, 2029$3,613,118 - $3,613,118
Microbial Programming of T-cell Migration from Gut to Brain
openJun 30, 2029$4,908,988 - $4,908,988
Determining the role of 90K on SARS-CoV-2
openJun 30, 2027$437,895 - $437,895
Mouse model of neonatal fungal colonization to study homeostasis and disease
openJun 30, 2027$245,250 - $245,250
B cell-dependent regulatory T cells
openJun 30, 2030$807,799 - $807,799
Advancing a Platform Technology for C. difficile Infection Treatment: the Promise of Antisense Oligonucleotides
openJun 30, 2027$426,875 - $426,875
Regulation of infectious spore formation in the fungal pathogen Coccidioides posadasii
openJun 30, 2027$438,038 - $438,038
Elucidating fungal and bacterial polymicrobial interactions during catheter-associated urinary tract infections
openJun 30, 2027$234,750 - $234,750
Colorado State University StARR Program in Infectious Disease and Immunology
openJun 30, 2030$209,164 - $209,164
Investigating the Metabolic Role of the Redox Cofactor F420 in Mycobacterium tuberculosis Hypoxic Persistence
openJul 14, 2029$54,538 - $54,538
Resources to Advance Pediatrics and HIV Prevention Science: Scientific and Quality/Regulatory Support Services
openJul 14, 2026$66,177 - $66,177
Glycopolymers as Cellular Glues
openJul 14, 2028$49,538 - $49,538
Development of a radiation countermeasure with sex-dependent radiation response.
openJun 30, 2027$170,800 - $170,800
Protective roles of CD180 and NOD1 in the protective immunity against cerebral Toxoplasma infection
openJun 30, 2027$423,500 - $423,500
The Ferret as a model for evaluation of antiviral efficacy against Venezuelan equine encephalitis virus
openJun 30, 2027$423,500 - $423,500
Defining STING Interactions that are Required for Rhinovirus Replication
openJun 30, 2027$423,803 - $423,803
Single cell analysis of dysregulated inducible DNA amplifications of immune response genes in Down syndrome
openJun 30, 2027$234,000 - $234,000
Human rotavirus egress and infection in association with extracellular vesicles
openJun 30, 2027$481,250 - $481,250
Investigating the contribution of a novel monocyte transcriptional state to sepsis immunopathogenesis and patient heterogeneity
openJun 30, 2030$197,640 - $197,640
Determining the contribution of glutaminase-dependent metabolism of dendritic cells to inflammatory diseases
openJun 30, 2030$751,138 - $751,138
Roles and regulation of tissue resident CD8 T cells during a persistent viral infection
openJun 30, 2029$3,194,992 - $3,194,992
Placating death eaters: Tuning macrophage metabolism and phenotype via nanoparticles
openJun 30, 2027$152,250 - $152,250
Investigating the development and regulation of the extrafollicular B cell response as a programmed response type
openJun 30, 2030$556,843 - $556,843
Targeting Multidrug-Resistant Pseudomonas aeruginosa with R Pyocins
openJun 30, 2027$439,896 - $439,896
Evaluation of the Mechanisms Underlying Induction and Maintenance Immunosuppression Impact on T Cell Function after Kidney Transplantation
openJun 30, 2029$3,106,301 - $3,106,301
Using proteomics to identify host cell death factors during M. tuberculosis infection
openMay 31, 2030$819,998 - $819,998
Maternal microbial exposure fundamentally shapes the CD8 T cell population at the maternal fetal interface
openJun 30, 2029$2,999,774 - $2,999,774
Dietary fat-activated colonocyte-macrophage ketone shuttle drives intestinal inflammation
openJun 30, 2029$2,893,480 - $2,893,480
Immune adaptations in acute pouchitis
openJun 30, 2027$409,320 - $409,320
Project 2: Development of vaccines in preclinical models to induce V2-apex bnAb responses
openMay 31, 2030$2,750,363 - $2,750,363
Mechanisms by which Glp-1 and Gip receptor signaling enhance airway epithelial barrier function
openJun 30, 2027$481,249 - $481,249
Defining the role of TRIM proteins in vector-borne bunyavirus infection
openJun 30, 2027$440,000 - $440,000
Inhibition of viral membrane fusion by interferon-induced proteins
openJun 30, 2029$2,297,892 - $2,297,892
Enhancing bacteriophage function with coevolution and synthetic biology
openJun 30, 2030$198,046 - $198,046
Effect of Borrelia burgdorferi-SIRPalpha Interaction on the Immune Response
openJun 30, 2027$429,000 - $429,000
Function of PfNCR1 at the PPM/PVM Interface
openJun 30, 2030$633,218 - $633,218
Interrogating NFKBID dependent humoral immunity to Toxoplasma gondii
openJun 30, 2027$435,875 - $435,875
Defining the mechanism of action of the broadly-active antiviral mosquito protein aBravo
openJun 30, 2027$401,185 - $401,185
Antibiotics, innate immunity, and dysbiosis in pediatric urticarial reactions
openJun 30, 2027$401,250 - $401,250
Innate iNKT Cells Shape Organ-Specific Pathogenesis in Plasmodium Infection
openJun 30, 2027$423,500 - $423,500
A cross-species signaling system in tick immunity and development
openJun 30, 2030$518,099 - $518,099
High Resolution, Whole Genome Tracking of Pathogen Transmission and Infection in the Neonatal ICU (NICU)
openJun 30, 2030$881,303 - $881,303
The dynamic interplay of human cells and Entamoeba histolytica during trogocytosis (cell-nibbling)
openJun 30, 2027$431,004 - $431,004
TIM-4 Signaling in NASH Liver Transplant Ischemia/Reperfusion Injury
openJun 30, 2027$433,125 - $433,125
The Road from Independence to Parasitism
openJun 30, 2027$418,016 - $418,016
Innate-adaptive immune bridging in gravidity-dependent immunity against placental malaria: a multi-omics approach
openJun 30, 2030$789,442 - $789,442
Biosynthetic and self-resistance investigations of kibdelomycin.
openJun 30, 2027$392,747 - $392,747
Development of an intein-based QF2 system for controllable protein expression in the nervous system of Aedes aegypti
openJun 30, 2027$423,125 - $423,125
Identification by High Throughput Screening of Inhibitors of the Mycobacterium tuberculosis ESX-1 and ESX-5 Type VII Secretion Systems – critical virulence determinants and novel drug targets
openJun 30, 2027$236,250 - $236,250
Multiplexed CRISPRa/i in primary immune cells to elucidate gene regulatory networks underpinning T cell development
openJun 30, 2027$405,497 - $405,497
Optimizing lipid RVn monophosphate prodrugs to maximize RVn-triphosphate delivery
openJun 30, 2029$3,082,513 - $3,082,513
Fungal Antigen Resources for Development of Vaccines and Diagnostics
openJun 30, 2030$1,193,457 - $1,193,457
Interrogating stress and viral shedding in a migratory bat model
openJun 30, 2027$376,932 - $376,932
Multimodal PET-CT imaging of SIVmac239 dynamics post-ART interruption
openJun 30, 2029$3,302,677 - $3,302,677
Autofluorescence is a tool to monitor radiation exposure and predict acute lethality
openMay 31, 2030$551,250 - $551,250
Therapeutic potential of mycobacteriophage LysB against Mycobacterium abscessus infections
openJun 30, 2030$689,051 - $689,051
TLE transcription cofactors in anti-viral and anti-tumor immunity
openJun 30, 2029$3,436,588 - $3,436,588
Conditional and female lethal approaches for mosquito control
openJun 30, 2030$588,514 - $588,514
Molecular mechanisms underlying persistent effects of early life exposure on lung function and remodeling
openJun 30, 2027$414,368 - $414,368
Decoding multidrug-resistant pathogen dynamics for clinically-relevant wastewater surveillance
openJun 30, 2030$534,000 - $534,000
Atlas of efflux and permeation determinants to advance antibacterial therapeutic discovery
openJun 30, 2030$1,120,070 - $1,120,070
Non-deletional CD8+ T cell tolerance
openJun 30, 2030$657,673 - $657,673
Next-Generation CMA/CMB Derivatives as Targeted Inhibitors of HIV Nef
openJun 30, 2029$3,110,884 - $3,110,884
New tools to facilitate drug discovery for pathogen proteasomes
openJun 30, 2027$438,500 - $438,500
Trypanosome flagellum structure, assembly, and mechanism
openJun 30, 2030$736,920 - $736,920
PD-1 BiKE: Targeting and Depleting PD-1 Positive Cells for Autoimmune Disease Treatment
openJun 30, 2027$423,500 - $423,500
Optimizing anti-microbial immunity by targeting Sts-1
openJun 30, 2029$3,125,627 - $3,125,627
Elucidating and targeting Siglec-9 function on mast cells
openJun 30, 2030$612,917 - $612,917
HIV-1 Integrase Interactions with Viral RNA
openJun 30, 2027$258,200 - $258,200
The role of the mRNA-based or Newcastle disease virus (NDV)-based vaccine platform in mucosal B cell priming and recirculation
openJun 30, 2027$464,750 - $464,750
Heterocyclic Inhibitors of QcrB as Novel Drugs for Infections Caused by Nontuberculous Mycobacteria
openJun 30, 2027$300,001 - $300,001
Viral mechanism for engaging lytic cycle promoting host transcription factors
openJun 30, 2027$402,150 - $402,150
Mechanistic studies of the complex regulation of the signaling histidine kinase GacS from Pseudomonas aeruginosa
openJun 30, 2027$422,355 - $422,355
Epigenetic Checkpoint Regulation of Naive T-cell Quiescence and Peripheral Tolerance
openJun 30, 2029$3,428,212 - $3,428,212
Mechanisms of age-related lung inflammation in pulmonary melioidosis
openJun 30, 2027$445,338 - $445,338
Molecular targets of the anti-apicomplexan compound, tartrolon E
openJun 30, 2027$423,500 - $423,500
Defining the Functions of Entero-Mammary T cells in Lactogenesis and Maternal-Offspring Immunity
openJun 30, 2030$562,500 - $562,500
Effect of Sneathia vaginalis on the amnion
openJun 30, 2027$404,273 - $404,273
Non-tuberculous Mycobacteria as triggers of Systemic Lupus Erythematosus
openJun 30, 2027$413,860 - $413,860
Role of branched-chain fatty acids in physiology and virulence of Staphylococcus aureus
openJun 30, 2029$3,021,822 - $3,021,822
Transmission dynamics and fitness of reemerging St. Louis encephalitis virus in mosquito vectors and West Nile virus naïve and immune avian reservoirs
openJun 30, 2029$3,161,373 - $3,161,373
Specialization and targeting of CD4+ tissue resident memory T cells in EAE
openJun 30, 2030$687,422 - $687,422
Mitigative effects of apigenin against gastrointestinal acute radiation syndrome (GI-ARS) in mice
openJun 30, 2027$158,500 - $158,500
Defining human xenoglycan-specific B cells
openJun 30, 2027$225,953 - $225,953
Elucidating the role of the SARS-CoV-2 ORF9b protein in virus replication
openJun 30, 2027$217,337 - $217,337
Salmonella-mediated delivery of Francisella type VI secretion system proteins as antigens to induce protective immunity
openJun 30, 2027$422,125 - $422,125
Understanding resistance and tolerance to nitroimidazoles in Mycobacterium tuberculosis
openJun 30, 2029$2,944,529 - $2,944,529
Understanding the Role of Tick Phospholipase A2 in Alpha-Gal Syndrome
openJun 30, 2027$235,822 - $235,822
Dual Role of TRPV2 in the STING-mediated innate immune response
openJun 30, 2029$2,129,684 - $2,129,684
Defining human and mouse non-canonical inflammasome responses to LPS
openJun 30, 2029$3,204,624 - $3,204,624
Identifying a protective role for interferon lambda in tuberculosis
openJun 30, 2027$413,002 - $413,002
Defining the interaction between adrenergic nerves and immune memory
openJun 30, 2030$555,120 - $555,120
Modulation of Neutrophil Function by Red Cell Exchange in SCD Patients
openJun 30, 2027$444,125 - $444,125
Role and Regulation of the Secreted Proteases of Staphylococcus aureus
openJun 30, 2030$480,522 - $480,522
Role of Mast cells in regulating inflammatory pathology of secondary lymphedema
openJun 30, 2027$497,136 - $497,136
Mechanism of inflammation in deficiency of adenosine deaminase 2
openJun 30, 2030$522,524 - $522,524
Antagonistic actions of IRF4 and BACH2 in regulating Germinal Center B cell fates and promoting Lymphomagenesis
openJun 30, 2027$441,098 - $441,098
Role of the ETS1 proto-oncogene protein in polyomavirus transcription
openJun 30, 2027$240,150 - $240,150
Health and Environmental Impacts of a Citywide Sanitation Intervention in Indiana
openJun 30, 2027$237,750 - $237,750
Harnessing translational research to advance understanding and clinical care in antibiotic allergy
openJun 30, 2027$443,527 - $443,527
Identification and enrichment of signature regions of antimicrobial resistant pathogen genomes for wastewater disease surveillance
openJun 30, 2027$421,673 - $421,673
Mechanisms of Immediate Non-IgE-mediated Drug Hypersensitivity Reactions (MIND-HR)
openMay 31, 2027$426,048 - $426,048
Creating an improved oncolytic virus through directed evolution and virus-driven expression of a cancer-targeting peptid
openJun 30, 2027$414,482 - $414,482
Identifying the molecular determinants of thermoadaptation and parasitic growth of Histoplasma capsulatum
openJun 30, 2027$556,375 - $556,375
Mechanisms of control of allergic skin inflammation by T regulatory cells
openJun 30, 2030$716,281 - $716,281
Disrupting Apicoplast DNA Replication in Plasmodium: Identifying Key Proteases for Antimalarial Therapy
openJun 30, 2027$385,816 - $385,816
Form with function: Rapid phenotypic carbapenemase testing to improve detection of carbapenemase-producing organisms
openJun 30, 2029$3,055,197 - $3,055,197
INSPIRE: Innovative Strategies for Personalized Immunotherapies and Reservoir Eradication
openMay 31, 2030$2,948,452 - $2,948,452
Real-Time Detection of Staphylococcus aureus Transmission in Hospital Settings
openJun 30, 2029$3,210,845 - $3,210,845
ASB13 Control of EBV Life Cycle in B Cell and Epithelial Cell Cancers
openJun 30, 2030$691,788 - $691,788
Structural studies of the full-length nucleocapsid protein of SARS-CoV-2
openJun 30, 2027$489,500 - $489,500
NON-CLINICAL STUDIES IN SUPPORT OF IND/NDA/BLA SUBMISSIONS
openJul 20, 2027$3,626,906 - $3,626,906
Vaccine-mediated cross-alphavirus protection for a live attenuated FDA licensed chikungunya virus vaccine
openJun 30, 2029$3,248,576 - $3,248,576
Chromatin architecture regulating trained immunity in antiviral NK cells
openJun 30, 2029$3,519,992 - $3,519,992
A Point of Care Urine Test to Aid Diagnosis of Aspergillosis
openJun 30, 2028$999,316 - $999,316
Ethical, Legal, and Social Implications of the Human Virome
openJun 30, 2027$427,625 - $427,625
Lymphoid-specific high-efficiency beta-catenin protein degradation
openJun 30, 2029$3,131,408 - $3,131,408
Role of Tregs in the acquisition and maintenance of Tconv anergy in transplantation tolerance
openJun 30, 2030$766,265 - $766,265
Using Chemical Synthetic Lethality to Identify New Antimicrobial Targets in Gram-Negative Bacterial Pathogens
openJun 30, 2027$451,000 - $451,000
Repository of Monoclonal Antibodies (RoMA) against Hamster and Guinea Pig Proteins
openJun 30, 2030$835,137 - $835,137
Unravelling the role of aDb2 as a novel complement receptor in lung injury
openJun 30, 2027$489,500 - $489,500
Harnessing the soluble guanylate cyclase pathway to alleviate early life RSV bronchiolitis
openJun 30, 2027$364,484 - $364,484
Novel point-of-care liquid biopsy for early detection of sepsis-associated organ damage
openJun 30, 2027$473,937 - $473,937
EHD4 and its role on HIV-1 infection
openJun 30, 2027$238,972 - $238,972
Airway Innate Immune Responses to Coccidioides Infection
openJun 30, 2029$3,075,549 - $3,075,549
ϕSa3 prophage as a molecular regulatory switch of Staphylococcus aureus β-toxin production
openJun 30, 2030$560,178 - $560,178
Modeling and validating dynamic accessibility to healthcare with system science approach
openJun 30, 2027$137,064 - $137,064
Antimicrobial peptides and antibiotic diffusion in sputum
openJun 30, 2027$423,500 - $423,500
Deciphering Central Nervous System Autoimmunity in Down Syndrome
openJul 28, 2028$37,336 - $37,336
Targeting host nuclear receptors for the resolution of Staphylococcus aureus Skin Infections
openJun 30, 2027$437,250 - $437,250
Establishing Human 2D and 3D Testicular Models to Elucidate Monkeypox Virus Tropism and Pathogenic Mechanisms in the Testes
openJul 31, 2027$156,500 - $156,500
Investigating the regulatory impact of the small regulatory RNA BecO on essential virulence factors in Pseudomonas aeruginosa
openJul 31, 2028$75,520 - $75,520
Ehrlichia modulation of RNA splicing to influence KIRREL1-regulated Hippo signaling
openJul 31, 2030$520,128 - $520,128
SSLs immune manipulation in S aureus colonization, infection, and a potential therapy against pneumonia
openJul 31, 2030$392,409 - $392,409
Memory Regulatory T cells in Recurring Malaria
openJul 31, 2030$650,020 - $650,020
Defining Protective IgGs to Food Allergy
openJul 31, 2030$806,466 - $806,466
C. albicans cell wall stress responses and TOR signaling
openJul 31, 2027$489,500 - $489,500
What do Pex4 and Pex22 do in apicomplexan membrane transport?
openJul 31, 2027$426,250 - $426,250
Impacts of non-antibiotic medications on microbiome-mediated protection against intestinal pathogens
openJul 31, 2027$125,809 - $125,809
Safer, More Effective Mpox/Smallpox Vaccine
openJul 31, 2027$431,750 - $431,750
A whole-cell inactivated vaccine for improved protection against tuberculosis
openJul 31, 2027$269,874 - $269,874
Environmental acquisition of ST398 Staphylococcus aureus by patients with chronic respiratory disease
openJul 31, 2027$77,750 - $77,750
An exploratory study of a new pH-responsive, ionizable hybrid nanocarrier for enchancing drug accumulation in bacterial biofilms
openJul 31, 2027$158,500 - $158,500
Novel, bio-inspired chloramine to treat cutaneous fungal infections without resistance generation potential
openJul 31, 2026$299,435 - $299,435
CD27-mediated immune suppression by HSPCs, innate immune cells or non-hematopoietic cells
openJul 31, 2027$427,625 - $427,625
Transcriptional and functional identity of human T follicular helper cells across tissues
openJul 31, 2027$246,750 - $246,750
Development of targeted nuclear receptor ligands as medical radiation countermeasures
openJul 31, 2027$157,500 - $157,500
Unraveling the Structural Architecture and Molecular Mechanisms of HIV-1 Cell-to-Cell
openJul 31, 2027$231,000 - $231,000
Defining the role of enterococci in reshaping Clostridioides difficile infection
openJul 31, 2030$812,200 - $812,200
The oral environment in food allergy development (ONEIDA)
openJun 30, 2029$6,732,986 - $6,732,986
Structure and mechanism of the polar tube invasion apparatus from microsporidian parasites
openJul 31, 2030$709,891 - $709,891
The Extracellular Matrix as a Determinant of Filovirus Infectivity.
openJul 31, 2027$480,249 - $480,249
Multi-Ancestry Genome-wide Association Analysis and Polygenic Risk Score of Moderate-to-Severe Asthma
openJul 31, 2027$458,634 - $458,634
The impact of antinuclear antibodies on alloimmune responses to renal transplants
openJul 31, 2026$332,690 - $332,690
Oklahoma ACE: Molecular Destruction of Autoimmune Disease to Aid Clinical Trail Success
openApr 30, 2029$400,579 - $400,579
Rickettsial CspA proteins and host microRNAs in exosome formation and pathogenesis
openJul 31, 2027$440,000 - $440,000
Optimization of a novel antimicrobial for pulmonary delivery to fight respiratory infections
openJul 31, 2027$184,375 - $184,375
Molecular mechanisms of enterovirus D68 viral entry mediated by the MFSD6 receptor
openJul 31, 2029$3,045,291 - $3,045,291
Immune responses associated with severe disease in patients with primary dengue infection
openJul 31, 2029$29,279 - $29,279
Structural and mechanistic study of bat NLRP6 inflammasome in detecting RNA viruses
openJul 31, 2030$451,836 - $451,836
Single arm trial of menstrual cups among economically vulnerable women to reduce Bacterial vaginosis and STIs through reduced harmful sexual and menstrual practices
openJul 31, 2027$139,891 - $139,891
Adaptation of an in vitro generated human skin model for tick feeding to study Borrelia burgdorferi transmission and colonization
openJul 31, 2027$417,845 - $417,845
Specialized Mitochondrial DNA Polymerases in African Trypanosomes
openJul 31, 2027$412,581 - $412,581
Improving herpes simplex virus vaccination efficacy and neonatal infection outcomes
openJul 31, 2027$49,538 - $49,538
UTS-1401: A Novel Mitigator of Radiation Injury
openJul 31, 2027$431,750 - $431,750
Decoding the Molecular and Antigenic Interactions in Orthopox Virus Entry
openJul 31, 2027$466,125 - $466,125
Influence of DNA methylation changes on gene expression from the inactive X chromosome in B cells
openJul 31, 2028$49,538 - $49,538
Chlamydia trachomatis modulation of host inflammasome
openJul 31, 2027$145,745 - $145,745
Animal Models to Develop New Regimens for S. aureus Implant-Associated Infections
openJul 31, 2029$3,266,329 - $3,266,329
Characterizing Respiratory Syncytial Virus Burden and Prevention in the United States
openJul 31, 2030$189,276 - $189,276
Diagnosis of tuberculosis and monitoring of treatment via RNA liquid biopsy
openJul 31, 2030$743,651 - $743,651
Differential regulation of cell cycle entry and apoptosis in cytolytic lymphocytes informed by primary immunodeficiency
openJul 31, 2030$764,591 - $764,591
Engineered Microbes to Mitigate Intestinal Radiation Damage
openJul 31, 2027$160,125 - $160,125
Phylogenetics, causal inference, and model diagnostics for longitudinal studies of infectious disease transmission and control
openJul 31, 2030$537,861 - $537,861
Regulatory mechanisms for nuclear cGAS
openJul 31, 2030$382,500 - $382,500
Uncovering the Sensory Mechanisms of Blood Detection by Mosquitoes Using Innovative Genetic Approaches
openJul 31, 2030$458,849 - $458,849
Multivariate machine learning analysis of blood-based RNA expression profiles to distinguish relapsing-remitting and progressive forms of multiple sclerosis
openJul 31, 2027$979,138 - $979,138
Replication and Evolution of Primate Lentiviruses.
openJul 31, 2029$2,505,639 - $2,505,639
Development of a novel mucosal CTL-based HIV vaccine.
openJul 31, 2027$423,500 - $423,500
Impact of breastmilk on Campylobacter jejuni survival
openJul 31, 2030$534,418 - $534,418
Host cell reprogramming by human papillomavirus E7 proteins
openJul 31, 2029$2,938,414 - $2,938,414
Antibiotic treatment failure of Klebsiella pneumoniae liver abscesses
openJul 31, 2027$427,625 - $427,625
Oral N-Acetylglucosamine as Anti-Neuroinflammatory Add-on therapy for Multiple Sclerosis (NANA-MS)
openJul 31, 2026$263,892 - $263,892
Genomic- informed development of a cheap, portable assay to rapidly profile drug-resistant bacterial infections
openJul 31, 2030$198,630 - $198,630
Transcriptional regulation of essential tissues by pioneer factor FoxA in schistosome parasites
openJul 31, 2028$37,703 - $37,703
Multi Parametric Total-Body Imaging of Immune Activation in Post Acute Sequelae of SARS-CoV-2 (PASC)
openJul 31, 2029$808,672 - $808,672
Paired inhibition of falciparum merozoite invasion
openJul 31, 2027$426,938 - $426,938
Mechanistic Study of HIV Gag in sequestering the CARD8 inflammasome
openJul 31, 2026$650,934 - $650,934
A collaborative cross mouse model of Salmonella Typhi Chronic Carriage
openJul 31, 2027$402,985 - $402,985
RNAi-mediated silencing methods for Xenopsylla cheopis, a primary vector forplague transmission.
openJul 31, 2027$153,000 - $153,000
Culturomic and metagenomic methods optimization to detect multi-strain C. difficile colonization and infection
openJul 31, 2027$233,250 - $233,250
Human cellular models of TB and innate immunity
openJul 31, 2027$489,500 - $489,500
Modulating drug efflux transporter expression on the macrophage reservoir of HIV
openJul 31, 2027$77,000 - $77,000
Validation of Chlamydia virulence determinants by complementation
openJul 31, 2027$431,750 - $431,750
Determining the role of antibody epitope specificity in regulating Fc effector functions
openJul 31, 2027$128,461 - $128,461
Exploring Factor H recruitment by Treponema pallidum to avoid complement-mediated killing
openJul 31, 2027$448,150 - $448,150
Molecular Basis of Receptor Interactions for Venezuelan Equine Encephalitis
openJul 31, 2027$155,454 - $155,454
Elucidating the immune function of the RNA helicase DDX6
openJul 31, 2027$454,288 - $454,288
Protease sensor for rapid and sensitive detection of Borrelia infections
openJul 31, 2027$436,236 - $436,236
Characterizing a novel hypoxia cell-cycle checkpoint in Cryptococcus
openJul 31, 2027$423,236 - $423,236
Therapeutic vaccine platform to boost immune responses in Tuberculosis
openJul 31, 2027$599,471 - $599,471
Mechanism of evasion of cyclic oligonucleotide-based anti-phage signaling system
openJul 31, 2027$453,750 - $453,750
Engineering commensal bacteria and probiotics for lactate conversion and treatment of sepsis
openJul 31, 2028$75,520 - $75,520
Assessing Time-to-Treatment Variability in Antiretroviral Penetration by Multimodal Imaging
openJul 31, 2030$1,414,502 - $1,414,502
A wastewater approach to viral transmission, evolution, and ecology
openJul 30, 2030$568,909 - $568,909
Spatial approaches for optimizing TB active case finding: an investigation of activity spaces, mobility patterns, and local burden of disease in Nairobi, Kenya
openJul 31, 2030$30,316 - $30,316
The Role of SSR42 in Virulence Factor Regulation in S. aureus
openJul 31, 2030$470,953 - $470,953
Deep Learning-Driven Biodosimetry for High-Throughput Radiation Triage via Chromosomal Aberration Detection
openJul 31, 2027$157,400 - $157,400
Anti-retroviral drugs to block HTLV-1 transmission in vivo
openJul 31, 2027$189,057 - $189,057
Inter-membrane lipid signaling for preserving Gram-negative outer membrane integrity and antibiotic resistance
openJul 31, 2027$430,375 - $430,375
Elucidating mechanisms of carbon dioxide detection in insects
openJul 31, 2028$49,538 - $49,538
HIV Drug Resistance in the New Antiretroviral Therapy Era in Kenya
openJul 31, 2029$181,923 - $181,923
Emerging Cockroach-associated Biocontaminants in Low-income Households
openJul 31, 2027$418,000 - $418,000
Elucidating the Role of MRSA SasF in Skin Colonization and Disease
openJul 31, 2027$38,093 - $38,093
Probing NADase function of bacterial Toll/interleukin-1 receptor (TIR) proteins: Starting with a CURE (Course-based Undergraduate Research Experience)
openJul 31, 2029$149,620 - $149,620
Programming Offspring Immunity By In Utero Exposure to Maternal Helminth Infection
openJul 31, 2027$451,000 - $451,000
Phenotypically amplified assay for rapid, automated determination of beta-lactam susceptibility
openJul 31, 2029$1,795,199 - $1,795,199
Developing a tick-borne Rickettsia isolate library.
openJul 31, 2027$160,500 - $160,500
Ebola Virus Life Cycle Modeling In Vivo
openJul 31, 2027$441,100 - $441,100
Evaluating human T cells specific for Mycobacterium tuberculosis antigens that are processed and presented by infected macrophages
openJul 31, 2030$813,450 - $813,450
Self-Administrated Multiplex Radiation Indicator (SAMURAI) Kit for field triage biodosimetry
openJun 30, 2030$542,053 - $542,053
Role of ZNF proteins in the establishment and maintenance of HIV latency
openJul 31, 2026$453,750 - $453,750
Mechanistic Target of Rapamycin (MTOR) in human and murine cryptococcosis
openJul 31, 2027$160,640 - $160,640
Characterization of P. aeruginosa sRNAs that are highly expressed in human chronic infections
openJul 31, 2030$775,184 - $775,184
Leveraging the sensitivity of antigen-specific T cells to interrogate disease mechanisms and identify therapeutic targets for Long COVID
openJul 31, 2027$175,428 - $175,428
Expanding Safe Water Access to Improve Health Outcomes in Appalachia: The Rural Water Filtration and Health (RWELL) Trial
openJul 31, 2030$832,818 - $832,818
Exploring polyamine toxicity and resistance in epidemic bacterial skin pathogens
openJul 31, 2029$2,976,652 - $2,976,652
STAT4 regulation of Th17 pathogenicity
openJul 31, 2030$632,423 - $632,423
Single-cell spatial-temporal understanding of the role of macrophage subsets in maintenance of lesion biology and local Mycobacterium tuberculosis infection outcome
openJul 31, 2027$450,500 - $450,500
Retroelement-mediated cis-regulation of embryonic hematopoiesis
openJul 31, 2027$434,375 - $434,375
Multivalent mRNA HIV vaccine using Envelopes from recently circulating viruses.
openJul 31, 2028$208,875 - $208,875
Therapeutic potential of targeting glia as an inflammatory mediator source and bacterial reservoir
openJul 31, 2027$413,542 - $413,542
Impact of Spatial and Social Determinants on Invasive Fungal Infection Risk
openJul 31, 2030$197,640 - $197,640
Clostridioides difficile Zinc-binding PBPs as anti-sporulation targets
openJul 31, 2029$2,872,722 - $2,872,722
Exogenous fatty acid utilization by Staphylococcus aureus
openJul 31, 2030$677,325 - $677,325
BioPROTAC-Mediated Degradation of HIV-1 Rev
openJul 31, 2027$227,588 - $227,588
Enhancing durability of V3 glycan vaccine responses in rhesus macaques
openJul 31, 2030$1,285,304 - $1,285,304
Evaluation of PEG-BPEI as a potential mitigator against gastrointestinal acute radiation syndrome
openJul 31, 2027$149,008 - $149,008
HIV Viral Load Testing Using CRISPR Cascade Signal Amplification
openJul 31, 2030$647,533 - $647,533
Cell specific roles of CD153 and CD30 in regulation of immune responses
openJul 31, 2027$441,375 - $441,375
Advancing lymphatic filariasis elimination with parasite genomic epidemiology
openJul 31, 2030$777,360 - $777,360
Role of Tick Metalloprotease Inhibitors in the Transmission of Borrelia burgdorferi
openJul 31, 2027$423,106 - $423,106
Statistical Methods to Leverage Immunologic Biomarkers and Complex Molecular Testing Data for Respiratory Diseases Vaccines Development
openJul 31, 2030$448,573 - $448,573
Hemozoin and liver stage malaria vaccine efficacy
openJul 31, 2027$183,276 - $183,276
Discovering accumulation guidelines and applying them to develop new antibiotics for Gram-negative pathogens
openJul 31, 2030$1,144,714 - $1,144,714
Activation and Evasion of the Inflammasome by Noncytotoxic Staphylococcus aureus
openJul 31, 2030$188,916 - $188,916
Mechanisms of HIV accessory protein mediated control of NK cell function
openJul 31, 2030$848,839 - $848,839
HIV Molecular Epidemiology (ME) Dashboard: Mapping HIV to Identify Prevention Gaps in Florida
openJul 31, 2030$812,427 - $812,427
Deciphering interactions between human T cells and cardiomyocytes in immune checkpoint inhibitor-related myocarditis
openJul 31, 2030$197,640 - $197,640
Validation of miRAD assay as a biodosimetry tool for radiological/nuclear triage applications in pediatric and geriatric population
openJul 31, 2027$159,075 - $159,075
Investigating structural and biochemical factors guiding concanamycin A biosynthesis
openJun 30, 2028$43,588 - $43,588
Nutrient acquisition and cyclic nucleotide signaling in Treponema pallidum as underpinnings of stealth pathogenicity
openJul 31, 2027$457,875 - $457,875
TCR-dependent and epigenetic mechanisms guiding influenza-specific CD4+ T cell responses in the lung
openJul 31, 2029$3,078,308 - $3,078,308
Selective Targeting of the PD-1+ HIV/SIV reservoir with novel anti-PD-1 chimeric antigen receptor T cells
openJul 31, 2030$862,398 - $862,398
Long-term impact of persistent parainfluenza virus infection
openJul 31, 2030$596,115 - $596,115
New role of NP Exoribonuclease in Lassa virus infection
openJul 31, 2030$576,501 - $576,501
Mechanisms of CD4 T cell help to myeloid cells in tuberculosis
openJul 31, 2029$2,863,501 - $2,863,501
B-SMART - Broadly neutralizing antibodies for SaRNA Mediated Antiviral Response Therapy
openJul 31, 2027$599,989 - $599,989
Multidimensional and longitudinal immune profiling of sepsis in Uganda
openJul 31, 2029$153,972 - $153,972
Control of intracellular Shigella in human macrophages.
openJul 31, 2026$80,477 - $80,477
Structural characterization of the elongasome and divisome in mycobacteria
openJul 31, 2030$492,000 - $492,000
Simultaneous Targeting of Immunoglobulin G and M Using Endopeptidase for Humoral Rejection in Xenotransplantation
openJul 31, 2027$444,125 - $444,125
A randomized controlled trial of a novel, evidence-based algorithm for managing lower respiratory tract infection in a resource-limited setting
openJul 31, 2027$107,296 - $107,296
SCH: New Bayesian Causal Structural Discovery and Reinforcement Learning Methods for Mental health in HIV Care
openJul 31, 2029$289,436 - $289,436
Novel therapeutics to treat TB by stimulating bacterial cAMP production
openJul 31, 2030$746,602 - $746,602
Specific Coxsackievirus B3 Binding Interactions with Bacteria
openJul 31, 2027$43,113 - $43,113
Developing an Intervention to Promote Early Introduction of Peanut and Egg to Reduce Food Allergy Risk
openJul 31, 2029$195,696 - $195,696
The Clinical History of Rectal and Urethral STIs among MSM: characterizing microbiome host immune interactions for diagnostic and vaccine advances
openJul 31, 2028$138,853 - $138,853
Sickle cell disease severity prediction from the magnetic signature and hemoglobin content of blood cells
openJul 31, 2027$150,220 - $150,220
Defining a Role for Atypical B Cells in RV-Induced Exacerbations of Allergic Asthma
openJul 31, 2027$38,921 - $38,921
Development and optimization of a peptide inhibitor of influenza virus splicing for broad-spectrum antiviral therapy
openJul 31, 2029$3,170,096 - $3,170,096
Evaluating the Functional Impact of Genetic Diversity on Malaria Vaccine Candidates
openJul 31, 2027$104,466 - $104,466
UCLA Rapid, Rigorous, Relevant Implementation Science Hub: Leveraging Implementation Science to End the HIV Epidemic
openJul 31, 2030$721,721 - $721,721
Classical dendritic cells (cDC1) govern cardiac allograft tolerance
openJul 31, 2029$36,673 - $36,673
Turicibacter modifies intestinal infection severity by modulating intestinal metabolites
openJul 31, 2027$262,410 - $262,410
Mechanisms of nuclear egress in herpesviruses
openJul 31, 2029$3,268,792 - $3,268,792
Informing Drug Synergy: Investigating Mycobacterial Membrane Protein Structure and Function
openJul 31, 2029$3,262,539 - $3,262,539
Novel Antiviral Agents Targeting Zika and Dengue Virus
openJul 31, 2027$80,000 - $80,000
Deciphering Genetic Susceptibility of Pemphigus through Immunomics
openJul 31, 2030$778,934 - $778,934
Development of antimicrobials based on principles of induced proximity
openJul 31, 2027$481,250 - $481,250
Determining the role of PARP14 in restricting HSV-1 replication
openJul 31, 2027$411,499 - $411,499
Dietary sugar-regulated recombinant protein production in the gut
openJul 31, 2027$427,625 - $427,625
Role of RNA modification in innate immune cell development and function
openJul 31, 2030$659,663 - $659,663
PS03, a bifunctional RNA therapeutic to induce exhaustion in diabetogenic T cells
openJul 31, 2026$380,000 - $380,000
A Novel Model for Development of Countermeasures to Mitigate Radiation-induced Cardiotoxicity
openJul 31, 2027$158,500 - $158,500
Non-sputum-based biomarkers for the detection of tuberculosis
openJul 31, 2030$850,711 - $850,711
Characterization of an RNA binding protein required for influenza virus replication
openJul 31, 2027$42,815 - $42,815
Leveraging prenatal tolerance to improve AAV/bNAb therapy outcomes in infancy
openJun 30, 2030$1,257,182 - $1,257,182
A Novel Strategy to Identify Protective T cell Epitopes for HPV Therapeutic Vaccine
openJul 31, 2027$131,166 - $131,166
Chemical composition-viability relationship of bioaerosols through spatial distribution and size-controlled measurements
openJul 31, 2027$429,000 - $429,000
Curing chronic Toxoplasma infection with novel and potent protease inhibitors
openJul 31, 2030$603,601 - $603,601
Exploiting the bacteriophage arsenal to discover novel classes of anti-biofilm agents
openJul 31, 2027$427,625 - $427,625
Epigenetic mechanisms of intestinal stem cell fate conversion in response to severe radiation injury
openJul 31, 2027$158,716 - $158,716
Impact of bat hibernation on metabolism and immunity to infection
openJul 31, 2030$464,296 - $464,296
Spatiotemporal interrogation of interactions of pneumolysin, pulmonary epithelium, and PMNs that result in age-associated susceptibility to Streptococcus pneumoniae disease
openJul 31, 2027$450,630 - $450,630
Biomarkers to identify regional exposure to radiation
openJul 31, 2027$156,000 - $156,000
IND-enabling development for IN-005, an inhaled muco-trapping mAb therapy against Influenza A
openJul 31, 2028$1,013,003 - $1,013,003
Development of Broadly Protective Vaccines against New World Arenaviruses
openJul 31, 2030$720,588 - $720,588
T Cell Alloreactivity and Organ Transplant Risk Stratification Models Using High-Resolution HLA and Genomic Data
openJul 31, 2030$606,609 - $606,609
Role of GRAIL in B cell tolerance and B-cell mediated inflammation
openJul 31, 2029$2,630,572 - $2,630,572
Dual function for an effector immunity protein in Pseudomonas aeruginosa biofilm biogenesis
openJul 31, 2027$52,538 - $52,538
HBV-specific T cell immunity in HBV/HIV coinfection
openJul 31, 2028$136,858 - $136,858
Role of Ca2+ in B. anthracis exosporium assembly
openJul 31, 2027$148,500 - $148,500
Translating germline-targeting HIV Env SOSIP immunization of infants: targeting bnAbs in early life
openJun 30, 2030$4,630,686 - $4,630,686
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