Funding Organization

National Heart Lung and Blood Institute

1000 opportunities

About

No description available for this funder.

Grants (1000)

Frontiers at the edge: Subpleural fibroblasts orchestrate pulmonary fibrosis progression

open

Mar 31, 2029$249,000 - $249,000

Screening and validation of miRNA targets for neurogenic hypertension.

open

Mar 31, 2033$1,008,719 - $1,008,719

Biomarkers and Predictors of Treatment Response in Chronic Anemia in Sickle Cell Disease

open

Mar 31, 2031$190,188 - $190,188

Genomic and Clinical Mechanisms and Prognostic Implications of Myocardial Lipomatous Metaplasia

open

Mar 31, 2028$169,020 - $169,020

Mapping Activated Microglia and Their Effect on Cognitive Deficits in Adults with Sickle Cell Disease

open

Mar 31, 2031$186,613 - $186,613

Comparative vertebrate neural crest contribution to the hematopoietic stem cell specification niche

open

Mar 31, 2028$140,809 - $140,809

Immunogen Core

open

Jun 30, 2030$234,367 - $234,367

Kir2.1 channel dysfunction underlies neurovascular coupling impairment in autism

open

Mar 29, 2029$38,224 - $38,224

Decoding the gene regulatory network of mammalian cardiac maturation

open

Mar 31, 2028$124,688 - $124,688

Unraveling Endothelial-CardiomyocyteCrosstalk in Cardiomyopathy: An Integrated Multimodal Approach

open

Jan 31, 2033$770,000 - $770,000

Mechanisms of SP-A and Its Genetic Variants in Regulating Lung Innate Immunity

open

Dec 31, 2027$105,705 - $105,705

Visualizing Sodium in Lymphatic Disease: a Translational Path

open

Feb 28, 2033$950,550 - $950,550

Novel pathways and mechanisms underlying disorders of platelet count and/or function

open

Jan 31, 2033$1,081,420 - $1,081,420

Elucidating the role of the tunica adventitia resident progenitor cells in vascular calcification

open

Mar 31, 2028$93,085 - $93,085

Pain phenotypes in advanced peripheral arterial disease

open

Mar 31, 2028$114,375 - $114,375

Role of TRPM7-Mediated Signaling in Vascular Remodeling in Abdominal Aortic Aneurysm

open

Mar 31, 2028$130,275 - $130,275

Exploring the Molecular Landscape of Lung Health and Aging Through a Multi-Omics Lens

open

Mar 31, 2028$170,570 - $170,570

Dynamics and plasticity of the hematopoietic stem cell niche

open

Jan 31, 2033$1,137,883 - $1,137,883

Developing cardiac organoids with deliberate heterogeneity for modeling sinus node dysfunction

open

Mar 31, 2028$232,500 - $232,500

Fatty Acid Metabolic Drivers of Right Ventricular Dysfunction in Heart Failure Associated Pulmonary Hypertension

open

Mar 31, 2031$190,188 - $190,188

Discovery of rare splicing variants in whole blood and lung

open

Jan 31, 2028$120,825 - $120,825

Regional Disparity of Skeletal Muscle Microvascular Dysfunction in Systolic Heart Failure

open

Mar 31, 2031$188,568 - $188,568

Role of Gasdermin-D in neonatal hyperoxia-induced systemic vascular remodeling and cardiac dysfunction

open

Feb 28, 2028$230,250 - $230,250

High-energy human milk diets in the first two weeks after birth to reduce the severity of respiratory morbidity in extremely preterm infants

open

Mar 31, 2029$180,860 - $180,860

Whole genome sequence interpretation for lipids to discover new genes and mechanisms for coronary artery disease

open

Mar 31, 2029$249,000 - $249,000

Modeling the Effect of Apolipoprotein LI Risk Variants on CVD Risk in African American E-cigarette Users Using Human Induced Pluripotent Stem-Cell-Derived Endothelial Cells

open

Mar 31, 2028$127,168 - $127,168

Mechanism of ketogenic diet-induced hypercholesterolemia

open

Mar 31, 2031$201,222 - $201,222

High-resolution phenotyping of the hemodynamic consequences of thoracic aortic aneurysm repair

open

Mar 31, 2028$143,461 - $143,461

The protein C pathway: Mechanisms, Structure-function, and Translation

open

Jan 31, 2033$863,954 - $863,954

Integrative Single-Cell Analysis of Aging-Associated Changes in Human Hematopoietic Stem Cell Heterogeneity

open

Jan 31, 2028$134,250 - $134,250

Early Immune Signatures of COPD: Linking Inflammation to Disease Progression

open

Dec 31, 2027$120,825 - $120,825

Longitudinal Examination of Food Insecurity and Cardiometabolic Health Risk in Hispanic/Latino Adolescents

open

Mar 31, 2031$191,636 - $191,636

ARDVARC-Advancing Rare Disorders: Vascular mAlformation Research Network with CaNVAS: Career Core

open

May 31, 2030$185,588 - $185,588

PSAT1 modified mRNA induces cardiac repair post-ischemic heart injury

open

Mar 31, 2029$375,000 - $375,000

Dissecting the role of vascular endothelial BMP9 signaling in lung transplantation

open

Feb 5, 2027$44,187 - $44,187

Molecular Analysis of Airway Secretory Cells in Health and Disease

open

Jan 31, 2028$249,000 - $249,000

Equitable Implementation of Remote Patient Monitoring in Pediatric Invasive Home Mechanical Ventilation Using Wireless Devices

open

Dec 31, 2026$117,750 - $117,750

Unraveling The Mechanism of Heart Failure in Hypertrophic Cardiomyopathy with Exercise CMR

open

Jan 31, 2030$777,258 - $777,258

Understanding and addressing the lack of and delayed screening for primary Aldosteronism

open

Dec 31, 2028$726,611 - $726,611

Analyzing effectiveness of ongoing natural experiments in telehealth

open

Dec 31, 2029$705,383 - $705,383

Aerosolized Chemically Modified Tetracycline Nanoformulation for the Treatment of Acute Respiratory Distress Syndrome

open

Feb 28, 2028$887,354 - $887,354

Hemostatic erythrocytes for acute non-compressible hemorrhage

open

Feb 28, 2027$195,000 - $195,000

Regulation of cardiac metabolism during Leukemia

open

Dec 31, 2029$549,796 - $549,796

Establishing the feasibility of measuring bereavement-related stress in a naturalistic setting

open

Feb 28, 2027$120,000 - $120,000

Immuno-Metabolic Regulation of Vascular Dysfunction by CD70

open

Feb 28, 2030$167,400 - $167,400

EQUITABLE: Equity in Treatment for Asthma Between Latinos and Whites

open

Dec 31, 2028$673,581 - $673,581

Precision Prediction of Right Ventricular Size, Function, and Outcomes in Patients with Repaired Tetralogy of Fallot

open

Feb 28, 2030$167,588 - $167,588

Deciphering links between Leukocyte Activation and Infections in VAD patients

open

Feb 28, 2029$608,874 - $608,874

Development of a Totally Implanted Left Ventricular Assist Device

open

Feb 29, 2028$1,024,635 - $1,024,635

Molecular and Translational Studies in Hematologic Disorders

open

Feb 28, 2032$1,276,908 - $1,276,908

Pulmonary Artery Endothelial Cell Endotypes and the Role of Anoikis Resistance in Pulmonary Hypertension

open

Dec 31, 2028$692,768 - $692,768

Sequential Multiple Assignment Randomized Trial to Reduce Food Insecurity and Improve Adherence in Patients with Hypertension

open

Feb 28, 2030$708,678 - $708,678

Artificial sweeteners and cardiovascular disease

open

Dec 31, 2028$756,574 - $756,574

Characterization of the roles of bivalent domains in CD4+ T cell differentiation

open

Feb 29, 2028$248,955 - $248,955

Integrated super-resolution CMR-deep learning to deconvolute passive and active causes of impaired relaxation

open

Dec 31, 2029$581,357 - $581,357

Reprogrammed Monocytes Improve Neovascularization in Peripheral Arterial Disease

open

Dec 31, 2028$528,179 - $528,179

Targeting Hypoxia-Inducible Factors (HIFs) for Heart and Lung Disease

open

Dec 31, 2031$564,445 - $564,445

Novel Insights into the Mechanistic Role of Small Rho GTPase in Chronic Cardiac Fibrotic Remodeling

open

Dec 31, 2029$542,663 - $542,663

Role of cardiac m6A methyltransferases

open

Dec 31, 2029$707,045 - $707,045

RNA methylation in the progress of heart failure

open

Dec 31, 2028$550,165 - $550,165

Neuroinflammation as a mediator of the exaggerated Piezo2 and Exercise Pressor Reflex in Peripheral Artery Disease

open

Mar 4, 2030$40,431 - $40,431

Hypertension, antihypertensive treatment, and uterine fibroid diagnosis in an integrated healthcare system

open

Feb 28, 2029$178,068 - $178,068

Investigating fibrinogen as a pathologic and targetable mediator of COVID-19-associated coagulopathy

open

Feb 29, 2028$391,250 - $391,250

Medial Arterial Calcification in Peripheral Artery Disease

open

Dec 31, 2028$761,042 - $761,042

Focal Myocardial Delivery of Small Molecule Nitroalkenes using Ultrasound Targeted Microbubble Cavitation to Improve Ventricular Recovery Following Myocardial Infarction

open

Dec 31, 2028$720,676 - $720,676

Phenotyping Net Immune State with MicroRNAs in Cardiac Transplantation

open

Jan 31, 2030$652,173 - $652,173

G6PD Deficiency and Atherosclerosis

open

Dec 31, 2027$323,000 - $323,000

Assessing myocardial fibrosis with spin locked MRI

open

Dec 31, 2028$756,947 - $756,947

Secondary Analysis of 3D Echo Images of the Right Ventricle to Compute 3D Surface Strain

open

Dec 31, 2026$117,000 - $117,000

Junctophilin-1 in the heart

open

Dec 31, 2028$650,691 - $650,691

Optimizing Effectiveness and Implementation of COPD Self-Management Treatment

open

Nov 30, 2029$725,088 - $725,088

Receptor-mediated Control of Pulmonary Ionocytes

open

Dec 31, 2029$551,863 - $551,863

Impact of prenatal exposures to copper from electronic nicotine delivery system (ENDS) aerosols on the immature neonatal pulmonary immune system and IL-10-mediated asthmatic responses

open

Jan 31, 2030$441,000 - $441,000

Applying reinforcement learning to create a precision medicine weight loss intervention

open

Feb 28, 2027$235,179 - $235,179

Preclinical Optimization and Design for Manufacturability of Immunoregulatory TEVGs

open

Feb 28, 2027$344,056 - $344,056

Development of platform technology to measure kinetics and equilibrium concentration of sickle hemoglobin polymerization in single RBCs for drug potency assessment and patient risk stratification

open

Feb 28, 2027$467,102 - $467,102

Liposomal azithromycin to treat cardiac inflammation

open

Feb 28, 2027$542,094 - $542,094

NET stabilization: mechanistic and therapeutic studies studying the role of NETs in thromboinflammatory disease

open

Feb 29, 2028$445,000 - $445,000

Minimizing myocardial damage and loss of cardiac function post myocardial infarction using Targeted PKC inhibitors 002 and 004.

open

Dec 31, 2026$1,488,899 - $1,488,899

Capitalizing on Artificial Intelligence to Capture Undiagnosed Structural Heart Disease from Electrocardiograms (CACTUS)

open

Jan 31, 2030$704,611 - $704,611

Developmental Origins of COPD

open

Mar 31, 2027$585,380 - $585,380

Investigating the Heterogeneous Intercellular Signaling of Hematopoietic Stem and Progenitor Cells and its Changes around the Circadian Clock

open

Mar 31, 2029$49,538 - $49,538

Short inhibitory RNAs in platelet and megakaryocyte function

open

Jan 31, 2029$541,366 - $541,366

Screening of novel compounds through the reversal of gene expression in idiopathic pulmonary fibrosis

open

Mar 31, 2027$542,402 - $542,402

Integrative Metabolomics of Sarcoidosis Diagnosis and Progression

open

Jan 31, 2030$760,374 - $760,374

Advancing Precision Medicine for ARDS and Sepsis

open

Mar 31, 2032$1,124,681 - $1,124,681

Mechanosensitive Mechanisms of Premature Calcification in Bicuspid Aortic Valve Disease

open

Mar 31, 2029$49,538 - $49,538

Investigating the role of SYNE1-Giant in Atrial Cardiomyopathy

open

Mar 31, 2030$42,277 - $42,277

Structure, Function and Drug Treatment of the Native Cardiac Sarcomere in Hypertrophic Cardiomyopathy

open

Mar 31, 2028$75,520 - $75,520

Locking and Unlocking Cardiac Maturation

open

Mar 31, 2032$1,114,748 - $1,114,748

The electrophysiological properties of embryos Transfer

open

Apr 30, 2028$612,607 - $612,607

The NF-kappaB modulator PDLIM2 as an intrinsic checkpoint of alveolar macrophages critical for lung innate immunity, inflammation and diseases

open

Jan 31, 2029$829,998 - $829,998

Inflammation-associated Autophagy Dysfunction

open

May 31, 2028$465,000 - $465,000

Role of circulating Osteopontin and of Innate Immune Cell CD44 in Tissue Injury-induced Remote Lung Inflammation

open

Jan 31, 2029$559,802 - $559,802

Manufacturing Process Intensification for Pluripotent Stem Cell-Derived Rare Red Cell Production

open

Mar 31, 2027$568,264 - $568,264

Chronic dehydration in sickle cell disease: An actionable biomarker to prevent vaso-occlusive episodes

open

Mar 31, 2027$131,050 - $131,050

The role of lamin B1 in normal and myelodysplastic hematopoiesis

open

Jul 31, 2027$508,817 - $508,817

Metabolic Reprogramming of the Alveolar Stem Cell Niche in Pulmonary Fibrosis

open

Mar 31, 2028$603,881 - $603,881

PROTECTIVE POISON AT HIGH ALTITUDE: THERAPEUTIC EFFECTS OF ELEVATED ENDOGENOUS CO FROM ADAPTIVE HMOX2 VARIANTS

open

Mar 31, 2027$42,596 - $42,596

The association of placental gene expression and newborn metabolic profiles in understanding childhood asthma pathogenesis

open

Mar 31, 2027$131,965 - $131,965

Pathogenic Mechanism and Therapeutic Approaches for Exercise Intolerance in Post-Acute Sequelae of COVID-19

open

Jan 31, 2029$633,045 - $633,045

A real-time monitoring and predictive device for cardiovascular surgeries and sepsis

open

Mar 31, 2027$412,250 - $412,250

Understanding the effect of post-concussive sleep disruption on glymphatic function in collegiate athletes

open

Jan 31, 2030$743,252 - $743,252

Personalized Stroke Risk Stratification in Atrial Fibrillation: Integrating Probabilistic Graphical Models and High-dimensional EHR Data for Interpretable Prognosis

open

Mar 31, 2030$540,771 - $540,771

Targeting Angiopoietin-like 4 (ANGPTL4) in Severe Community Acquired Pneumonia

open

Jan 31, 2029$827,909 - $827,909

Molecular physiology of Phox2b-expressing RTN chemoreceptor neurons

open

Jan 31, 2029$744,305 - $744,305

Continuous Respiratory Monitoring Platform for Classifying Apnea of Prematurity

open

Feb 28, 2027$371,021 - $371,021

Prenatal Care and Postnatal Outcomes for Publicly Insured Children with Congenital Heart Defects

open

Mar 31, 2030$168,480 - $168,480

p16 Cellular Senescence and Vascular Dysfunction in Sleep Apnea

open

Apr 30, 2028$749,508 - $749,508

The role of cancer in cardiovascular disease

open

Jan 31, 2032$1,102,957 - $1,102,957

Promoting weight-related health in the next generation of adolescents and young adults:A comprehensive program of research

open

Mar 31, 2032$1,057,905 - $1,057,905

Deep Learning Assessment of the Right Ventricle: Function, Etiology, and Prognosis

open

Jan 31, 2027$248,979 - $248,979

Genetic and Molecular Mechanisms of Heart Disease

open

Jan 31, 2032$1,052,778 - $1,052,778

A Digital Shared Decision-Making Aid to Improve Patient-Centered Outcomes in Implantable Cardioverter-Defibrillator (ICD) Decisions among Older Patients

open

Feb 28, 2029$718,958 - $718,958

Dual frequency intravascular ultrasound for super-resolution imaging of vasa vasorum and thin fibrous cap of vulnerable atherosclerotic plaques

open

Jan 31, 2029$726,205 - $726,205

Podocyturia based assay as a predictive biomarker for systemic vascular diseases

open

Mar 31, 2027$306,101 - $306,101

Defining the Innate Immune Cell Profile of Factor VIII Immunity

open

Mar 31, 2028$393,856 - $393,856

Exploring Functional Divergence in Human and Chimpanzee Arteries: Implications for Cardiovascular Disease

open

Apr 22, 2028$43,071 - $43,071

Uncovering the mesenchyme-specific roles of planar cell polarity in lung development

open

Jan 31, 2029$607,194 - $607,194

Interactive roles of cardiorespiratory fitness and adiposity on recovery of impaired glucose and vascular control after physical inactivity

open

Mar 31, 2028$422,894 - $422,894

Protection of hematopoietic stem progenitor cells from endogenous DNA damage

open

Mar 31, 2028$372,282 - $372,282

The Role of End-Binding Protein 2 and Microtubule Network in Inherited Cardiac Arrhythmias

open

Mar 31, 2028$248,363 - $248,363

Magnetic Rotational Platform for Coronary Lesions

open

Mar 31, 2027$413,595 - $413,595

Post-Operative Biomarker-Guided Precision Medicine for Cardiovascular Risk Reduction

open

Mar 31, 2027$392,037 - $392,037

Sensory neuronal mechanism for development of house dust mite induced airway hyperreactivity

open

Apr 30, 2030$387,116 - $387,116

Novel pathogenesis of LVNC

open

Mar 31, 2030$683,048 - $683,048

Evaluating the effects of preschool access policies on parents' cardiovascular health and health inequities: a quasi-experimental population-based investigation

open

Aug 31, 2027$50,781 - $50,781

Clinical CT Imaging for Screening and Subtyping of Pulmonary Hypertension in COPD

open

Feb 28, 2029$812,189 - $812,189

Defining the Role of Platelet ABO(H) Blood Group Antigens in Hemostasis and Thrombosis

open

Apr 30, 2028$445,708 - $445,708

Circadian disruption and cardiometabolic risk during the transition from adolescence to young adulthood

open

Feb 28, 2030$691,124 - $691,124

Facilitating Health System Implementation of Physical Activity Screening and Referral to Community-Based Programs: Exercise is Medicine Greenville

open

Apr 30, 2030$702,964 - $702,964

A randomized double-blind, placebo-controlled phase 2 clinical trial of intravenous citrulline for vaso-occlusive crisis in sickle cell disease

open

Apr 30, 2029$859,704 - $859,704

Endothelin 1 in iron handling in sickle cell disease

open

Jan 31, 2030$573,821 - $573,821

CD90-targeted nanoparticles for in vivo hematopoietic stem cell gene therapy

open

Feb 28, 2029$756,008 - $756,008

Role of Cofilin-1 in Mitochondrial Quality Control Influencing Mechanisms of Airway Epithelial Dysfunction in Chronic Bronchitis

open

Feb 28, 2029$749,203 - $749,203

Multi-scale characterization of antigen-polymerized immune complexes underlying thrombotic pathologies triggered by adenoviral-vectored vaccines

open

Feb 28, 2029$601,677 - $601,677

Senescence Cardiomyopathy

open

Feb 28, 2029$631,261 - $631,261

Improved diagnostics for heparin induced thrombocytopenia

open

Jan 31, 2029$542,442 - $542,442

Psychosocial stress-induced neurometabolic dysfunction as a mediator ofpostpartum cardiovascular disease

open

Apr 30, 2029$727,080 - $727,080

Basolateral brain endothelial cilia and its role in promoting vascular stability

open

Mar 31, 2029$661,170 - $661,170

Targeting Interleukin-17 inflammatory Axis in CTEPH

open

Feb 28, 2029$723,084 - $723,084

Vascular and neural mechanisms of chronic lower leg heating in pregnant women with obesity

open

Apr 30, 2030$670,890 - $670,890

Triangulating causal effects of sleep, inflammation, and cardiometabolic disease

open

Nov 30, 2027$41,700 - $41,700

Treating secondary cardiomyopathies by mimicking the adaptive hepatic glucose fasting response

open

Jun 30, 2026$612,000 - $612,000

Artificial Intelligence Imaging Biomarkers of Longitudinal Cardiovascular Stress

open

Nov 30, 2028$733,096 - $733,096

Mechanisms underlying maintenance of cardiac chamber identity in zebrafish

open

Apr 30, 2029$788,513 - $788,513

Long non-coding RNA MCRL1 regulates human cardiac and hematopoietic differentiation via interacting with β-Catenin

open

Feb 28, 2029$571,132 - $571,132

Defining targetable vulnerabilities in UBA1-mutated VEXAS HSCs for clonal eradication

open

Feb 28, 2029$780,120 - $780,120

Adventitial Fibroblast Phenotypic Modulation in Atherosclerosis

open

Mar 31, 2030$686,252 - $686,252

Niche-specific endothelial mechanisms regulating the extravasation of hematopoietic stem cells

open

Feb 28, 2030$734,607 - $734,607

A novel mechanism regulating genome-wide mRNA expression in hypoxic lung disease

open

Feb 28, 2029$562,225 - $562,225

Hypertension-associated Trained Immunity in Myeloid Cells is a Determinant of Atherosclerosis

open

Mar 31, 2029$786,060 - $786,060

Mechanisms that Enhance and Suppress HIV-1 Resistance in Gene Edited Primary Human Cells

open

Apr 30, 2028$249,000 - $249,000

Finding and pushing the limits of macrophage efferocytosis in atherosclerosis

open

Apr 30, 2032$686,640 - $686,640

Systemic Corticosteroid Pharmacokinetics and Pharmacodynamic Biomarker Identification in Children with Asthma and Obesity

open

Apr 30, 2030$188,073 - $188,073

Hypothalamic oxytocin neuron activation rescues cardiac metabolism through cardiac cholinergic signaling in type 2 diabetes

open

Apr 30, 2027$43,903 - $43,903

Role of GLUT1 in diabetic cardiomyopathy

open

Feb 28, 2029$749,360 - $749,360

Gut Microbe-Derived Lipids Shape Chronic Inflammation in Cardiometabolic Disease

open

Feb 28, 2029$743,302 - $743,302

A Pediatric Atlas of Upper Airway Shape

open

Jul 31, 2026$120,379 - $120,379

Epigenetic Regulation of Heart Failure with Preserved Ejection Fraction

open

Feb 28, 2029$699,133 - $699,133

Investigating the function of RBC-TLR7 in Sepsis

open

Jan 31, 2029$392,660 - $392,660

Chaperone-Mediated Autophagy in Cardiac Fibrosis

open

Feb 28, 2029$785,198 - $785,198

Targeting the stromal niche for tissue-resident lymphocytes in asthma

open

Feb 28, 2029$636,843 - $636,843

Purifying platelets with high-throughput microfluidics for pediatric and neonatal transfusions

open

Feb 28, 2029$678,241 - $678,241

Understanding Cardiac Mitochondrial Quality Control Through the Lens of Barth Syndrome

open

Feb 28, 2029$648,582 - $648,582

Intersection of the PPARγ-RhoBTB1-Cullin-3 Pathway and Renin-Angiotensin System in Blood Pressure, Vascular Function and Arterial Stiffness

open

Apr 30, 2032$1,092,000 - $1,092,000

Attenuation of sepsis-induced microvascular permeability and inflammation with the GLP-1R agonist liraglutide.

open

May 31, 2028$3,000 - $3,000

Post-transcriptional regulatory networks in Chronic Obstructive Pulmonary Disease

open

Feb 28, 2030$708,063 - $708,063

The Prognostic and Predictive Impact of Telomere Length in Fibrotic Interstitial Lung Disease

open

Feb 28, 2030$704,444 - $704,444

BIOREPOSITORY OF LUNG DISEASE-SPECIFIC HUMAN INDUCED PLURIPOTENT STEM CELLS (BHIPSC-LUNG). BHIPSC-LUNG TASK AREA A CORE ADMINISTRATIVE TASKS

open

May 1, 2026$141,504 - $141,504

Amelioration of Cardiac Fibrosis Using Diverse Cell Village Human Cardiac Organoids

open

May 1, 2026$79,756 - $79,756

Software-guided Operative Planning of MitraClip Placement

open

Mar 31, 2027$1,065,759 - $1,065,759

Equitable and accessible wearable device for continuous calculation of blood loss for postpartum hemorrhage

open

Feb 28, 2030$639,165 - $639,165

The role of microglial glutaminase in HIV-induced sleep deficits

open

Feb 28, 2029$684,184 - $684,184

Skeletal Muscle Health Protects Vascular Function in Obesity

open

Feb 28, 2029$728,574 - $728,574

Migration and resolution, lung microenvironment and mechanisms: examining the diverse responses of neutrophils during S. pneumoniae pneumonia and acute lung injury

open

Feb 28, 2029$744,784 - $744,784

Novel approaches for cardiac reprogramming: Exosome delivery of reprogramming miRNAs and repressor targeting siRNAs

open

Feb 28, 2029$496,367 - $496,367

Novel liver-mediated mechanisms in hypertension and cardiac dysfunction

open

Feb 28, 2029$561,515 - $561,515

E-cigarettes Epigenetically Augment Transgenerational Abdominal Aortic Aneurysm

open

Feb 28, 2029$355,000 - $355,000

NHLBI TRANS-OMICS FOR PRECISION MEDICINE (TOPMED) INFORMATICS RESEARCH CENTER (IRC) YEAR 2

open

May 14, 2026$4,916,999 - $4,916,999

Epigenetic Regulation of Trained Immunity in Thoracic Aortic Aneurysms and Dissections

open

Mar 31, 2030$673,400 - $673,400

The role of protease activated receptor 2 in the initiation and progression of abdominal aortic aneurysm

open

Mar 31, 2029$740,338 - $740,338

Mechanical and Metabolic Pathways Underlying MYBPC3 Hypertrophic Cardiomyopathy

open

Apr 30, 2030$167,400 - $167,400

The Role of Leiomodin1 in Hypoxic Neovessel Maturation

open

Feb 28, 2030$687,517 - $687,517

DLK1 regulates HSC quiescence through phase separation mediated inhibition of receptor signaling

open

Feb 28, 2029$646,305 - $646,305

Mitochondria in cardiomyocyte-fibroblast transcellular cross-talk

open

Mar 31, 2029$639,621 - $639,621

SUBPOPULATIONS AND INTERMEDIATE OUTCOMES IN COPD (SPIROMICS) III - SPIROMICS - TASK AREA B

open

Jun 17, 2026$197,163 - $197,163

SIDS, failed autoresuscitation, and a novel serotonergic brainstem-cerebellar circuit

open

Mar 31, 2029$664,632 - $664,632

Novel mechanisms and therapeutics for Tyrosine Kinase Inhibitor-induced Cardiotoxicity

open

Feb 28, 2030$697,952 - $697,952

Unraveling the Mechanisms of Opioid-Induced Airway Constriction: A Path towards Novel Therapeutics for Opioid Overdose

open

Apr 30, 2028$249,000 - $249,000

Thiol redox signaling in aortic aneurysm

open

Feb 28, 2029$758,462 - $758,462

BIOINFORMATICS CORE

open

Apr 30, 2030$337,604 - $337,604

Immunoregulatory Role of Conventional Dendritic Cell Type 2 in Allergic Lung Inflammation

open

Feb 28, 2029$730,764 - $730,764

Intravenous oxygen for the treatment of cardiac arrest

open

Mar 31, 2029$859,295 - $859,295

An Image-Guided Microrobotic Drug Delivery Method for Preventive Vascular Interventions

open

Mar 31, 2030$703,523 - $703,523

Proteomic profiling of heart failure in Hispanics/Latinos

open

Feb 28, 2029$816,079 - $816,079

BIOREPOSITORY OF LUNG DISEASE-SPECIFIC HUMAN INDUCED PLURIPOTENT STEM CELLS (BHIPSC-LUNG). IPSC TASK AREA B - SCIENTIFIC PROJECTS

open

May 1, 2026$590,460 - $590,460

Vascular Smooth Muscle Vps34 in Pulmonary Arterial Hypertension

open

Apr 30, 2028$244,589 - $244,589

Prevention of remodeling by image guided epicardial delivery of hydrogels to the heart

open

Mar 31, 2029$758,862 - $758,862

Bioengineering strategies for exogenic organ production

open

Apr 30, 2027$279,750 - $279,750

Hv1 in Pulmonary Hypertension

open

Mar 31, 2029$522,794 - $522,794

Mutation-Specific Calmodulin Kinase II Activation in Hypertrophic Cardiomyopathy

open

May 31, 2027$42,171 - $42,171

MEOX2: A Critical Regulator of Alveolar Fibroblast Function

open

Mar 31, 2029$721,826 - $721,826

iPSC-derived VSMC for high-throughput screening of small molecules for aortic aneurysm

open

May 31, 2027$122,625 - $122,625

Elastic exosome-releasing conductive patches for heart repair

open

Mar 31, 2029$682,678 - $682,678

Inhalation Delivery of Exosome and microRNA Therapy for Lung Fibrosis

open

May 31, 2027$404,462 - $404,462

Developing a topical beta blocker formulation as a targeted therapeutic for infantile hemangioma

open

May 31, 2026$306,804 - $306,804

Adverse Effects of Neonatal CPAP on Lung Development

open

Mar 31, 2029$740,196 - $740,196

Determining how inflammation is regulated in RUNX1-Familial Platelet Disorder with Associated Myeloid Malignancies

open

May 31, 2028$54,538 - $54,538

A deep learning artifact removal method for CPR continuity throughout the shock decision in AEDs

open

Mar 31, 2029$752,495 - $752,495

Reconceptualizing Disease Progression in Pulmonary Fibrosis

open

Mar 31, 2030$717,018 - $717,018

Catheter-injectable, engineered biomaterial for sustained Neuregulin-1 delivery to the myocardium

open

Mar 31, 2029$739,248 - $739,248

The role of LDL in hemostasis

open

Mar 31, 2029$737,111 - $737,111

Cobinamide as a disease-modifying treatment for Marfan Syndrome: optimizaation of absorption

open

May 31, 2027$405,781 - $405,781

EOI:: IMPLEMENTING THE PRESIDENT'S DEPARTMENT OF GOVERNMENT EFFICIENCY COST EFFICIENCY INITIATIVE (MARCH 19, 2025)::EOI BILATERAL MODIFICATION TO DESCOPE WORK FOR NATIONAL FERRET RESOURCE AND RESEARC

open

Sep 22, 2026$1,432,732 - $1,432,732

Targeting mitoNEET in pulmonary hypertension

open

Mar 31, 2029$559,740 - $559,740

Molecular Basis for cMyBP-C HCM variants

open

Mar 31, 2029$730,764 - $730,764

Emulating hypothetical target trials to establish the comparative effectiveness of biologics in asthma

open

Mar 31, 2030$793,948 - $793,948

Development of Methodologies to Reveal the Role of the Blood Microbiome in the Gut-Lung Axis

open

May 31, 2028$249,000 - $249,000

Impact of Adaptive Immune System on Cardiac Electrophysiology

open

Mar 31, 2029$741,112 - $741,112

Impact of sequence changes on key intrinsically disordered regions of cardiac troponin

open

Apr 30, 2029$776,791 - $776,791

RADX BLUEPRINT MEDTECH TRANSLATOR COHORT 2 - COMMERCIALIZATION CENTER - HEAL

open

Jun 1, 2026$511,206 - $511,206

CD4+ T cell Immunity in the Respiratory Tract

open

May 31, 2032$1,063,324 - $1,063,324

Dissecting the Protective Role of Cardiac Hsp90ß Ablation/Inhibition

open

Apr 30, 2030$605,253 - $605,253

Ischemic cardiac injury regulates sleep through an immune-mediated heart-brain axis

open

Apr 30, 2029$843,607 - $843,607

Engineered biomaterials for promoting lymphatic regeneration in lymphedema

open

Apr 30, 2029$502,294 - $502,294

Cardiotoxicity of catecholamine metabolism by monoamine oxidase with obesity

open

Jun 4, 2027$35,626 - $35,626

Novel cysteinyl leukotriene receptor signaling in regulating cellular, and molecular events in lung inflammation

open

Feb 28, 2029$567,874 - $567,874

Controlling Neuropilin-2 Signaling to Improve Lymphatic Function

open

Apr 30, 2029$865,694 - $865,694

Role of cardiac clock misalignment in promoting arrhythmias in swine and donor human hearts

open

Mar 31, 2030$721,041 - $721,041

Intrinsic Inhibitory Mechanisms of Vagal Nociceptors

open

Mar 31, 2029$458,767 - $458,767

Controlling the Niche to Control Clonal Hematopoiesis

open

Apr 30, 2029$802,301 - $802,301

Weinstein Cardiovascular Development and Regeneration Conference

open

May 31, 2026$30,000 - $30,000

Selective B Cell Depletion Using Engineered T Cells As A Curative Treatment For Acquired Thrombotic Thrombocytopenic Purpura

open

Mar 31, 2029$810,875 - $810,875

Development of a Provider-Focused Intervention to Improve Health Outcomes in Pediatric Sickle Cell Disease

open

May 31, 2030$156,340 - $156,340

Platelets as regulator of non-neurological complications of ischemic stroke

open

Mar 31, 2029$779,952 - $779,952

Pathogenic role of IL-39/IL-39R signaling in graft-versus-host disease

open

Mar 31, 2029$586,203 - $586,203

Core C: Cell and Tissue

open

Mar 31, 2030$393,848 - $393,848

Investigating the Role of Vascular Injury and Physiologic Dead Space in the Acute Respiratory Distress Syndrome - Supplement

open

May 31, 2026$75,600 - $75,600

A multi-sensor machine learning approach to precision sleep tracking for nightshift workers

open

Apr 30, 2030$678,710 - $678,710

Reduced hypusination of EIF5A impairs free ubiquitin generation resulting in the development of HFpEF

open

Apr 30, 2027$126,387 - $126,387

The Impact of Late Preterm Steroids in Reducing Neonatal Respiratory Morbidity in the US

open

Apr 30, 2030$667,776 - $667,776

Determining the function of Tbx1 in the pharyngeal endoderm for aortic arch development

open

Jun 15, 2028$49,538 - $49,538

Identification of Pro-aging Thrombospondin-1 Producing Cells Within the Bone Marrow Niche

open

Jun 16, 2028$41,180 - $41,180

Bioengineered lymphatic regenerating platform for treatment of breast cancer related lymphedema

open

Apr 30, 2029$491,029 - $491,029

CORONARY ARTERY RISK DEVELOPMENT IN YOUNG ADULTS (CARDIA) STUDY - CHICAGO FIELD CENTER

open

Jun 30, 2026$697,031 - $697,031

Common and distinct metabolic pathways of pulmonary sarcoidosis phenotypes and endotypes

open

Jun 30, 2027$249,000 - $249,000

CORONARY ARTERY RISK DEVELOPMENT IN YOUNG ADULTS (CARDIA) STUDY - UNIVERSITY OF MINNESOTA FIELD CENTER.

open

Jun 30, 2026$556,968 - $556,968

Molecular mismatch as a marker for immunologic risk in heart transplant recipients

open

Mar 31, 2030$819,532 - $819,532

Translational control in heart and lung disease by RNase A family

open

Jun 30, 2028$34,370 - $34,370

Mechanisms of Impaired Granulopoiesis Due to CLPB Mutations

open

Jun 30, 2028$445,000 - $445,000

Impacts of Phosphofructokinase-2 on Cardiac Electrophysiology and Function in Diabetes

open

Jun 30, 2028$38,024 - $38,024

The Role of Lymphatic Endothelial Alpha Globin in Heart Failure

open

Jun 30, 2027$38,992 - $38,992

Macropinocytosis and Pulmonary Fibrosis

open

Dec 31, 2028$570,395 - $570,395

Paramedic Evaluation for Acute COPD Exacerbation: the PEACE Intervention

open

Jun 30, 2030$167,398 - $167,398

Novel Device for Treating Mitral Regurgitation

open

Dec 31, 2026$298,368 - $298,368

Elucidating anti-angiogenic tyrosine kinase inhibitor-induced vascular dysfunction

open

Jun 30, 2028$248,999 - $248,999

Calcium-dependent autoregulation of vasopressin neurons in a rodent model of heart failure.

open

May 31, 2028$249,000 - $249,000

Extending neutrophil survival in neutropenia-related pneumonia

open

Mar 31, 2029$676,748 - $676,748

Investigating cellular adaptation to one-carbon metabolism perturbation

open

Jun 30, 2028$39,551 - $39,551

Administrative Supplements to Existing NIH Grants and Cooperative Agreements (administrative supplement to 5K23HL171951, Adaptation and pilot testing of a family-centered intervention to improve long-

open

Jun 30, 2026$37,799 - $37,799

Defining the role of G3BP1 in vascular development

open

Jun 30, 2028$49,538 - $49,538

CORONARY ARTERY RISK DEVELOPMENT IN YOUNG ADULTS (CARDIA) STUDY - OAKLAND FIELD CENTER

open

Jun 30, 2026$743,884 - $743,884

CORONARY ARTERY RISK DEVELOPMENT IN YOUNG ADULTS (CARDIA) STUDY - BIRMINGHAM FIELD CENTER

open

Jun 30, 2026$743,202 - $743,202

Financial Toxicity in Chronic Obstructive Pulmonary Disease

open

Jun 30, 2026$101,360 - $101,360

Examining The Interplay Between Atrial Fibrillation, Anticoagulation, and Retinal Stroke - An Instrumental Variable Approach

open

Jun 30, 2027$242,250 - $242,250

Early Life Stress and Cardiovascular Disease Risk: Identifying the Role of Microbial Metabolites

open

Jun 30, 2028$249,000 - $249,000

Alveolar Epithelial Stress Signaling in Lung Fibrosis

open

Mar 31, 2030$667,795 - $667,795

Characterizing Sleep Health, Sleep Disorders, and Cognitive Functioning After Heart Transplantation

open

Jul 1, 2027$80,046 - $80,046

Use of donor-derived cell-free DNA for risk stratification and post-treatment monitoring of lung transplant patients at risk for chronic lung allograft dysfunction

open

May 30, 2028$248,999 - $248,999

Stem Cells, Cell Therapies, and Bioengineering in Lung Biology and Lung Diseases

open

Jun 30, 2026$35,000 - $35,000

[25-009098] NHLBI, ITAC REQUIRES RENEWAL OF BP LOGIX BUSINESS PROCESS AUTOMATION SOFTWARE IN ORDER TO CONTINUE ITS USE IN THE NHLBI DOCUMENT WORKFLOW PROJECT. POP 07/05/2025 - 07/04/2026.

open

Jul 4, 2026$62,837 - $62,837

Personalizing Heart Failure Treatment with Genomics: A Clinical Trial to Understand the Mechanisms and Validate a Polygenic Risk Score for Beta-Blocker Response

open

Apr 30, 2030$619,882 - $619,882

Lung-derived complement in pneumonia

open

Apr 30, 2028$546,742 - $546,742

CaMKII and Endothelial SK Channel Function in Diabetic Coronary Microcirculation

open

Nov 30, 2028$76,313 - $76,313

Adapting a pediatric weight management program for implementation via telehealth

open

Jul 31, 2027$141,509 - $141,509

Sorting high extracellular vesicle secretors for optimal cell therapy

open

Apr 30, 2029$729,703 - $729,703

Cellular Therapies and Transfusion Medicine in Trauma and Critical Care Medicine

open

Jun 30, 2026$30,000 - $30,000

ReMOTE-BP: Research and Mentorship for Optimizing Treatment and Evaluation of Blood Pressure

open

Apr 30, 2030$130,065 - $130,065

Understanding the genetic and immunologic basis of autoimmune hemolytic anemia (AIHA) in a novel canine model system

open

Apr 30, 2030$516,056 - $516,056

Hexokinase 1 mitochondrial binding and its role in cardiac endothelial cell function and the development of HFpEF

open

Apr 30, 2029$735,838 - $735,838

Time-restricted eating: Is it an efficacious tool for weight loss maintenance

open

Jun 30, 2028$248,999 - $248,999

A Novel Platelet-Inspired Nanotechnology to Restore Hemostasis in Patients on Antiplatelet Agents

open

Jun 30, 2027$944,676 - $944,676

US Ten Day Seminar on the Epidemiology and Prevention of Cardiovascular Diseases and Stroke

open

Jun 30, 2026$45,000 - $45,000

MUSICO: An in silico platform for evaluating the effects of disease and drug effectiveness in HCM and DCM cardiomyopathies

open

Jul 14, 2026$297,720 - $297,720

Aortic dissection flap division by novel electrosurgical catheter facilitates aortic endograft landing zones

open

Dec 31, 2026$395,306 - $395,306

Commercialization Readiness Pilot Program support for: HATS-OFF

open

Jun 30, 2026$500,000 - $500,000

Non-canonical ERAD as a Regulator of Cardiac Hypertrophy

open

Dec 31, 2026$70,924 - $70,924

"Outside-in” Model of Cardiac Pacemaking: Extracellular Mediated Automaticity

open

Apr 30, 2029$668,783 - $668,783

Function and Regulation of MEIS1 in Vascular Disease

open

Jun 30, 2028$247,729 - $247,729

Determining genetic mechanisms that drive in vitro hematopoiesis

open

Jun 30, 2028$445,000 - $445,000

Concurrent targeting of inflammation and the inhibition of the fibrinolytic system to increase the efficacy of empyema treatment

open

Jun 30, 2027$499,585 - $499,585

The Interaction of Estradiol and Platelet Biology: A Mechanistic Exploration of Sex Dimorphisms in Coagulation

open

Jun 30, 2030$163,277 - $163,277

Atomic-level Structural-omics of Platelet Membrane Proteins via Multi-scale Structural Biology Approaches

open

Jun 30, 2027$121,003 - $121,003

Screening for Cardiac Amyloidosis with a Blood Biomarker in Minority Populations – SCABB-MP

open

May 31, 2029$416,849 - $416,849

Mitochondrial Derived Peptides in Chronic Obstructive Pulmonary Disease

open

Jun 30, 2027$258,516 - $258,516

Minimally Invasive Targeted Injection of Thermoresponsive Hydrogels for Cardiomyopathy

open

Apr 28, 2029$695,865 - $695,865

Chronic myosin activation as an agonist of cardiac mechanosensory pathways

open

Jul 14, 2028$42,780 - $42,780

High-resolution tracking of T cell differentiation to predict and control alloreactive disease

open

Jun 30, 2027$131,211 - $131,211

The impact of glycocalyx degradation on ARDS pathogenesis and outcomes

open

Jun 1, 2030$188,740 - $188,740

Targeting Epithelial WNK1 to Enhance Airway Host Defense

open

Jun 30, 2030$169,560 - $169,560

Cardiovascular Structure and Function in the Mucopolysaccharidoses

open

Apr 30, 2030$852,280 - $852,280

Inflammatory responses in human hematopoietic stem cells: the effect of aging and clonal hematopoiesis

open

Jun 30, 2030$166,644 - $166,644

OPT-FRESH: Optimizing Online Purchasing of Fruits, Vegetables, and Legumes for Low-Income Families

open

Apr 30, 2030$719,140 - $719,140

Molecular characterization of frailty and functional limitations in HFpEF

open

Jun 30, 2030$173,352 - $173,352

COMPASS Ancillary NeuroDevelopmental Outcomes(CAN-DO)

open

Apr 30, 2030$776,754 - $776,754

HIGH THROUGHPUT GENOTYPING AND DNA SEQUENCING FOR STUDYING THE GENETIC CONTRIBUTIONS TO HUMAN HEALTH AND DISEASE: WHOLE GENOME SEQUENCING FOR COZEN (NCI)

open

Jul 16, 2027$317,275 - $317,275

HIGH THROUGHPUT GENOTYPING AND DNA SEQUENCING FOR STUDYING THE GENETIC CONTRIBUTIONS TO HUMAN HEALTH AND DISEASE: WHOLE GENOME SEQUENCING FOR BEEBE-DIMMER (NCI)

open

Jul 16, 2027$262,500 - $262,500

Air pollution sensitivity in pediatric asthma

open

Jun 30, 2030$135,000 - $135,000

Identification of Computational Phenotypes in Pediatric Status Asthmaticus and Determination of Treatment Effect

open

Jun 30, 2030$156,899 - $156,899

Single Molecule Enzymology with Printed Carbon Nanocircuits

open

Jun 30, 2029$621,546 - $621,546

Dendritic cell lysosomes in immune checkpoint inhibitor-associated myocarditis

open

May 31, 2027$112,822 - $112,822

FunctIonal coaGulation and HemosTasis after IntraCerebral Hemorrhage (FIGHT-ICH)

open

Apr 30, 2030$829,103 - $829,103

Alveolar epithelial glycocalyx resilience in women during ARDS

open

Jun 30, 2030$761,615 - $761,615

A Clinical Decision Support Questionnaire to Identify Barriers to Blood Pressure Control

open

Jun 30, 2027$222,750 - $222,750

Predicting the hemodynamic response to mitral valve interventions with pressure-volume analysis

open

Jun 30, 2030$172,800 - $172,800

2025 Molecular and Cellular Biology of Lipids Gordon Research Conference and Gordon Research Seminar

open

Jun 30, 2026$34,325 - $34,325

Phosphate dysregulation as a driver of age-related vascular disease

open

May 31, 2027$138,523 - $138,523

Uncovering the Mechanisms that Enable Cardiac Progenitors to Build the Linear Heart Tube

open

May 31, 2027$134,998 - $134,998

Cooperative Modulation of Piezo Channels

open

Apr 30, 2029$636,822 - $636,822

Microbial-derived metabolites potentiate airway hyperresponsiveness in obesity-associated asthma

open

Apr 30, 2029$696,473 - $696,473

Protecting colonic mucus to mitigate acute intestinal graft-versus-host disease

open

Jun 30, 2026$454,814 - $454,814

Identification of Novel Epigenetic Regulators of lymphocyte Development

open

Jun 30, 2028$249,000 - $249,000

Building a Sedation Minimization Culture

open

Jun 30, 2030$180,936 - $180,936

Weight loss maintenance following an intervention

open

Jun 30, 2027$234,000 - $234,000

2025 Angiogenesis Gordon Research Conference and Gordon Research Seminar

open

Jun 30, 2026$20,000 - $20,000

2025 Lung Development, Injury and Repair Gordon Research Conference and Gordon Research Seminar

open

Jun 30, 2026$10,000 - $10,000

Developing a Comprehensive Care Pathway for Vascular Access Delivery in Hospitalized Children

open

Apr 30, 2030$155,321 - $155,321

1/2 PREEMPT: Prospective RandomizEd Evaluation and Management of Premature aTherosclerosis

open

Jun 30, 2027$3,886,403 - $3,886,403

SUBPOPULATIONS AND INTERMEDIATE OUTCOMES IN COPD (SPIROMICS) III

open

Jul 24, 2026$7,037,497 - $7,037,497

2/2 PREEMPT: Prospective RandomizEd Evaluation and Management of Premature aTherosclerosis

open

Jun 30, 2032$952,993 - $952,993

Hyperpolarized Xenon-129 MRI as a predictive biomarker for mitigating radiation-induced lung injury

open

Jun 30, 2030$191,913 - $191,913

Genetic ancestry effects on molecular and complex traits in TOPMed

open

Apr 30, 2029$804,982 - $804,982

Mechanistic insights into factor VIII inhibitor formation and eradication

open

May 31, 2026$155,165 - $155,165

CDK13 function in heart development and congenital heart disease

open

Jun 30, 2029$701,842 - $701,842

The Synergistic Effects of Menopause and HIV on Cardiovascular Disease Risk in Women

open

Jul 31, 2030$198,549 - $198,549

The Role of Blood-Brain Barrier Disruption on Ischemic Brain Injury and Cognitive Impairment in Sickle Cell Disease

open

Apr 30, 2030$195,846 - $195,846

Membrane-cytoskeleton interactions in megakaryocytes and platelets

open

Apr 30, 2029$604,301 - $604,301

Cell Identity and Functional Diversity of Sinoatrial Node Pacemaker Cell Subpopulations in the Physiology and Pathology of Cardiac Pacemaking

open

May 31, 2030$556,295 - $556,295

Evaluating Whether Treating Elevated Blood Pressure in the Inpatient Setting Impacts Patient Outcomes: the ACT-BP pilot

open

Jul 31, 2027$362,250 - $362,250

Methylphenidate to Address Executive Functioning Impairment in Pediatric Patients with Sickle Cell Disease

open

Jul 31, 2027$277,500 - $277,500

Postdoctoral Research Training in Lung Injury and Inflammation

open

Jul 31, 2030$407,052 - $407,052

Fibroblast-mediated resolution of basal metaplasia in lung fibrosis

open

Apr 30, 2029$695,421 - $695,421

Deciphering One Carbon Metabolism Defect in Heart Failure

open

Jun 30, 2027$169,020 - $169,020

Integrating deep learning, magnetic resonance imaging and genomics to study myocardial fibrosis

open

Jul 31, 2030$166,240 - $166,240

Empowering Cardiovascular Health in Custodial Grandparents (ECG)

open

Jul 31, 2028$197,160 - $197,160

Mechanisms of Cardiac Myosin Heavy Chain Gene Regulation

open

May 31, 2029$761,152 - $761,152

Plasminogen activator inhibitor 1 (PAI1) as a therapeutic target for maternal endothelial dysfunction in preeclampsia

open

Jun 30, 2030$806,978 - $806,978

Analysis of 24-h Blood Pressure Dysregulations Using Population-Based and Clinical Cohorts Data

open

Jul 31, 2027$222,000 - $222,000

Support your Heart: Feasibility trial of a cardiovascular health intervention for young adults

open

Jul 31, 2027$356,733 - $356,733

Cardiac Output and Renal Perfusion Alterations in the Development of Acute Kidney Injury in Cardiac Surgery

open

May 31, 2030$197,640 - $197,640

Secondary Analysis of Noninvasive Imaging Biomarkers for the Early Prediction of Single Ventricle Failure

open

Jul 31, 2027$234,000 - $234,000

Deep learning to link normal variation in aortic valve hemodynamics to pathogenesis of aortic stenosis

open

Jul 31, 2030$722,299 - $722,299

Airspace Candida Colonization and Lung Injury (AirCCoLIN)

open

Apr 30, 2030$719,195 - $719,195

ILC2s as drivers of lung dysfunction in response to early-life inflammation

open

May 31, 2029$740,709 - $740,709

Examining Anti-Factor VIII IgM in Propagation of the Immune Response to Factor VIII in Hemophilia A

open

Jul 31, 2027$234,750 - $234,750

REACH-SPIROMICS: Research on Environmental Aeroallergens, COPD, and Health in SPIROMICS

open

May 31, 2029$1,340,292 - $1,340,292

Post-transcriptional regulation of vascular homeostasis by RNA-binding proteins

open

May 31, 2030$618,450 - $618,450

Digitally Enhanced Cognitive-Behavioral Therapy for Adolescents with Depression and Obesity

open

Jul 31, 2028$226,778 - $226,778

Enhancing the Force Validated Heart Valve Surgical Planning Tool

open

Jul 31, 2028$414,982 - $414,982

High-flow portable oxygen concentrator for long-term oxygen therapy

open

Jul 31, 2027$1,213,182 - $1,213,182

Dependence of radiosensitivity of lymphocyte subtypes on proton dose and LET and its impact on immune suppression

open

Jul 31, 2027$37,598 - $37,598

(1/2) Statins to Prevent Cancer Associated Venous Thromboembolism (STAT-CAT): CCC

open

Jul 31, 2026$2,290,286 - $2,290,286

Statistical Methods for Information Synthesizing Using Multiple Existing Longitudinal Cohort Studies

open

May 31, 2029$500,660 - $500,660

Equol Supplementation for Improving Vascular Function in Postmenopausal Women with CKD: Efficacy and Mechanistic Role of GPER

open

Jul 31, 2030$162,384 - $162,384

Computed tomography for early detection and phenotyping of pulmonary hypertension associated with chronic obstructive pulmonary disease with implications for treatment

open

Jul 31, 2030$171,858 - $171,858

Role of Angiotensin II in Cardiogenic Shock Pathophysiology and Outcomes

open

May 31, 2030$189,000 - $189,000

Precision PET attenuation correction for combined PET/MR imaging of cardiac sarcoidosis

open

May 31, 2030$739,466 - $739,466

Connecting Molecular and Cellular Contractile Dysfunction in Cardiomyopathy

open

May 31, 2030$694,754 - $694,754

Oxidation-Specific Epitope IgA in Pulmonary Fibrosis

open

May 31, 2030$806,901 - $806,901

Hypoxia-inducible factor(HIF)-driven modulation of alveolar regeneration

open

Jul 31, 2030$159,624 - $159,624

Lung epithelial cell-derived C3 in acute lung injury

open

Jul 31, 2027$595,668 - $595,668

Clinical Implementation of Blood Pressure Polygenic Risk Score: A Randomized Clinical Trial

open

May 31, 2030$734,722 - $734,722

Investigating Histone Acetylation Modulator Function in Alveolar Regeneration and Disease Pathogenesis

open

Jul 31, 2027$130,593 - $130,593

Erythroblastic island macrophages in normal erythropoiesis and disordered erythropoiesis in polycythemia vera

open

Apr 30, 2029$801,628 - $801,628

Lung vascular ILC3 subpopulation in anti-bacteria immunity and vasculature regeneration

open

Apr 30, 2029$814,387 - $814,387

Pulmonary neuroimmune determinants of immunoglobulin production against pneumonia

open

Apr 30, 2030$718,661 - $718,661

Mucin Biosynthesis and Transport Mechanisms in Respiratory Health and Disease

open

Jul 31, 2028$249,000 - $249,000

Macrophage Factor XIII-A in Provisional Extracellular Matrix Modification and Epithelial Repair during Acute Lung Injury

open

Jul 31, 2030$163,790 - $163,790

High-throughput spatial proteomics in pulmonary research with FLASH multiplex imaging

open

Jul 31, 2026$312,148 - $312,148

Spatiotemporal visualization of adenylyl cyclase signaling

open

Jul 31, 2028$249,000 - $249,000

Control of multilineage hematopoiesis by 5' cap-proximal modification

open

May 31, 2030$164,160 - $164,160

A Novel Fully-Polymeric, Biomimetic Prosthetic Mitral Valve Constructed from Clinically-Proven Materials to Improve Durability, Performance, and Overall Outcomes

open

Jul 31, 2026$306,102 - $306,102

TranExamic Atomized for Pediatric post-Operative Tonsillectomy hemorrhage (TEAPOT)

open

Jul 31, 2027$398,822 - $398,822

Developing a framework for designing the next generation of pediatric ARDS trials

open

Jul 31, 2030$180,174 - $180,174

Biological Mechanisms of the Infarct Borderzone

open

May 31, 2029$765,288 - $765,288

Leveraging Drosophila to identify novel and conserved regulators of cardiomyocyte polyploidy

open

May 31, 2027$125,983 - $125,983

Patterns of Long-term Cigarette Smoking Behavior on CVD Risk: Implications for Clinical Practice and Public Health

open

Jul 31, 2027$231,000 - $231,000

Role of Aldehyde Dehydrogenase 2 in Resolution of Fibroproliferative ARDS

open

Jul 31, 2027$189,000 - $189,000

New win methods for addressing multiple and composite outcomes in cluster-randomized trials

open

May 31, 2029$706,573 - $706,573

Elucidating the Sexual Cycle of HIV/AIDS-Related Pneumocystis Pneumonia

open

May 31, 2029$508,041 - $508,041

EPIC-LT: Eliminating PGD through Inhibition of CCR5 in Lung Transplantation

open

Jul 31, 2028$301,840 - $301,840

Elucidating the Role of Microenvironment Mechanics in Regulating Cardiac Myofibroblast Plasticity

open

Jul 31, 2028$248,431 - $248,431

Focused Imaging as a Novel Diagnostic Strategy for Aortic Stenosis

open

May 31, 2030$793,868 - $793,868

Translational Light-Based Intervention Strategies for Improving Sleep and Circadian Health in Early Childhood

open

Jul 31, 2030$172,085 - $172,085

The role of sex chromosomes in neonatal hyperoxic lung injury

open

May 31, 2028$49,538 - $49,538

Receipt of GLP-1 Receptor Agonists Among Rural Patients with Obstructive Sleep Apnea

open

Jul 30, 2027$89,860 - $89,860

Multi-omic network methods for mapping molecular trajectories of age-related lung diseases

open

Jul 31, 2030$140,403 - $140,403

Understanding Pulmonary Fibrosis Through the Integration of Complex Occupational and Environmental Exposure Assessments (PF-OEM)

open

Jul 31, 2030$190,998 - $190,998

Metabolic Reprogramming in Experimental Deep Vein Thrombosis and Resolution

open

May 31, 2029$765,223 - $765,223

Sustainable Open-Source Software Tools for Simulating Cardiac Dynamics

open

Jul 31, 2027$459,838 - $459,838

Investigating Student-Level Outcomes of Equity-Focused Implementation Mapping in a Cluster Randomized Trial to enhance the impact of Universal School Meals

open

Jul 31, 2027$237,750 - $237,750

Lung Injury Biomarkers to Endotype Respiratory Trajectories in Established Bronchopulmonary Dysplasia: The LIBERATE-BPD Study

open

Jul 31, 2030$179,330 - $179,330

Protein phosphatase 2A mediates influenza-induced inhibition of lung alveolar defense

open

Jul 31, 2028$49,538 - $49,538

Weight Bias Reduction Intervention with Nursing Students Using Simulation: The BRAVE Study

open

Jul 31, 2028$432,585 - $432,585

E-cadherin deficient epithelium drives airway fibrosis in idiopathic subglottic stenosis

open

May 31, 2029$752,541 - $752,541

Blood Pressure Control Advancing Refugee Health Equity (BPCARE): an RCT of adherence

open

May 31, 2030$688,525 - $688,525

Functional Contributions of the Noncoding Genome in Atherosclerosis Risk Factors

open

Jul 31, 2027$129,137 - $129,137

Regulation of Intravascular Triglyceride Hydrolysis

open

Apr 30, 2032$1,102,500 - $1,102,500

RECK in Pulmonary Fibrosis

open

Jul 31, 2027$229,500 - $229,500

The role of HMGB1 in the lung response to bacterial injury

open

Apr 30, 2030$656,988 - $656,988

Targeting Senescent Macrophages to Improve Heart Failure Outcomes

open

May 31, 2030$651,967 - $651,967

Hepatocyte TMEM141 in Lipoprotein Metabolism

open

May 31, 2029$744,453 - $744,453

Sodium Pump, Sex Hormones, and Thrombosis

open

May 31, 2029$498,153 - $498,153

The role of the protein C system in trauma induced coagulopathy and thromboinflammation: mechanisms and targeted therapy.

open

May 31, 2029$760,083 - $760,083

Targeting breathing limitations to improve functional outcomes in HFpEF

open

Jun 30, 2028$249,000 - $249,000

Identifying Druggable Genetic Factors Underlying Radiation-induced Heart Disease

open

Jul 31, 2027$160,818 - $160,818

Coronary Vascular Resilience by Modulation of Mitochondrial ROS in Endothelium

open

May 31, 2029$651,380 - $651,380

Optimal Ventilator Management in Patients with ARDS on ECMO

open

Jul 31, 2030$178,846 - $178,846

CAROTID-MAP Carotid Atherosclerotic Risk Assessment Through Imaging andPrediction

open

May 31, 2030$771,485 - $771,485

Macrophage Polarization and Function in GVHD

open

Jul 31, 2030$151,092 - $151,092

OPTImal vasoPRESsor in persistent pulmonary hypertension of the newborn (OPTIPRES)

open

Jul 31, 2030$164,916 - $164,916

Platelets as therapeutic and diagnostic entity in fibromuscular dysplasia

open

Jun 30, 2027$118,919 - $118,919

Tobacco Treatment Specialist Training for Clinical Pharmacists to Advance Service Delivery for People Living with HIV

open

May 31, 2030$630,139 - $630,139

Functional characterization of genes and genetic variants associated with hypoplastic heart syndrome in Drosophila

open

May 31, 2029$777,016 - $777,016

A Multi-Component Remote Care Intervention for Rural Patients Living with Heart Failure

open

Jul 31, 2030$170,601 - $170,601

Regulation of bone marrow homing by hematopoietic stem cell vesicles

open

Jul 31, 2030$153,117 - $153,117

An Investigation of Omics for Bronchopulmonary Dypslasia

open

Jul 31, 2030$192,672 - $192,672

Impact of obesity and diabetes on coronary microvascular defects in HFpEF

open

Jun 30, 2027$169,020 - $169,020

Regulation of coagulation and thrombosis by C1 inhibitor

open

Jul 31, 2029$788,721 - $788,721

Understanding Sarcoidosis Susceptibility and Disease Burden Through Multi Omics

open

Jun 30, 2029$778,266 - $778,266

Hematopoietic cells and chemokine regulation in abdominal aortic aneurysm associated thrombosis

open

Jun 30, 2027$156,276 - $156,276

Unveiling the Atheroprone Role of Novel Mechanosensitive Histone Modification

open

May 31, 2030$535,556 - $535,556

Inhaled Vitamin D as a Protectant Against Respiratory Infections and Environmental Pollutants

open

Jul 31, 2027$40,752 - $40,752

Effects of Manually Recorded or Automatically Transmitted Home Blood Pressures with or without Automated Patient Feedback on Hypertension Care

open

Jul 31, 2030$793,184 - $793,184

Iron Deficiency in Cystic Fibrosis: Characterization of Clinical Impact and Treatment Effects

open

Jul 31, 2030$195,459 - $195,459

Enhancing Cardiovascular Risk Prediction and Treatment Response in Sleep Apnea Patients Using Advanced AI-based Transformer Models in Multi-Modal Sleep Data

open

May 31, 2029$816,472 - $816,472

Sex, HIV, and Air Pollution Effects on Post-TB Lung Disease (SHAPE PTLD)

open

May 31, 2030$561,226 - $561,226

(2/2) Statins to Prevent Cancer Associated Venous Thromboembolism (STAT-CAT): DCC

open

Jul 31, 2032$862,130 - $862,130

Enhance Cell Therapies for Peripheral Arterial Disease Using Human-Compatible Protease-Based Controls

open

Jul 31, 2027$410,449 - $410,449

The Role of Diet in COPD Rehospitalization

open

Jul 31, 2030$198,654 - $198,654

Mitochondrial Mechanisms in Asthma

open

Apr 30, 2030$732,225 - $732,225

Defining the major signaling mechanism which controls spontaneous cardiomyocyte proliferation in the Neonatal Stage

open

May 31, 2030$746,800 - $746,800

Characterizing a High-Reliability Implementation Program for Sepsis: Sepsis Tools AND Accurate Reporting of Outcome Differences (STANDARD) Study

open

May 31, 2029$814,313 - $814,313

Purinergic Signaling in Fibroblast Activation and Lung Fibrosis

open

May 31, 2029$728,577 - $728,577

Fractional flow reserve versus Angiography for Multivessel Evaluation (FAME) 3 Extended

open

Jun 30, 2030$769,846 - $769,846

Elucidating Drug Interactomes for Cardiac Protection by SGLT2 Inhibitors

open

May 31, 2027$131,085 - $131,085

Impact of PIGA Loss on Hematopoietic Stem Cell Function

open

May 31, 2030$786,456 - $786,456

Applying digital phenotypes and epigenetics to understand clinical outcomes in acute hypoxemic respiratory failure without acute respiratory distress syndrome (NAHRF)

open

Jul 31, 2030$169,344 - $169,344

Mitochondrial Gene Editing in Human Cardiomyocytes

open

May 31, 2029$773,479 - $773,479

The Farm Effect and Asthma Risk: Determining the Multi-Omic Immune Cell Landscape in Amish and Hutterite Children

open

Jul 31, 2027$246,000 - $246,000

Multi-component Lifestyle Intervention to Improve Outcomes in Black Adults with Chronic Kidney Disease

open

Jul 31, 2026$772,621 - $772,621

Multi-Omics Approaches for the Diagnosis and Risk Stratification of Pulmonary Fibrosis-Associated Pulmonary Hypertension

open

Jul 31, 2030$175,392 - $175,392

Endothelial cell targeting of factor VIII for hemophilia A

open

May 31, 2029$888,836 - $888,836

Multimodal Characterization of Cardiac-Neurodevelopmental Genes

open

Jul 31, 2027$267,000 - $267,000

Targeting Macrophage Populations to Attenuate Pulmonary Hypertension Associated with Sickle Cell Disease

open

Jul 31, 2027$111,626 - $111,626

Aminopeptidase N Driven Signaling in the Development of Pulmonary Hypertension

open

Jun 30, 2028$249,000 - $249,000

Solving the paradox of neural inhibition in pacing breathing

open

Apr 30, 2029$673,512 - $673,512

Platelet Regulation of Monocyte Responses in Vascular Inflammation

open

Apr 30, 2029$573,261 - $573,261

Immunogenetic risk factors for exacerbations in African American people with COPD

open

Jul 31, 2027$222,750 - $222,750

Discovering aging-associated genetic modifiers and therapies for anthracycline-induced cardiotoxicity

open

May 31, 2029$680,583 - $680,583

Role of Altered Mitochondrial dynamics in Graft Versus Host Disease

open

May 31, 2030$758,539 - $758,539

Role of BMP signaling in cardiac neural crest development

open

Jun 30, 2027$150,876 - $150,876

Investigating the pro-regenerative potential of Pontin in the heart.

open

May 31, 2029$833,594 - $833,594

Stoichiometric, adhesion, and contractile deficits in desmoplakin cardiomyopathy

open

May 31, 2029$651,349 - $651,349

Deciphering the role of GFPT2 in radiation-induced cardiovascular disease

open

May 31, 2029$760,982 - $760,982

Determining the role of CD163+ blood monocytes and lung macrophages in Progressive Pulmonary Fibrosis

open

Jul 31, 2030$188,892 - $188,892

A Biobehavioral Approach to Explore the Migration-Food Insecurity Nexus as a Social Determinant of Cardiovascular Health

open

May 31, 2029$609,850 - $609,850

Right Ventricular Response to Exercise Among Patients with Chronic Obstructive Pulmonary Disease

open

May 1, 2030$190,825 - $190,825

Developing a spatiotemporal lineage map of heart development

open

Jun 30, 2029$865,286 - $865,286

Unfixed, xenogeneic extracellular matrix for crimp damage-resistant and regenerative transcatheter heart valve prostheses

open

Jul 31, 2026$496,255 - $496,255

A Novel Articulating Stylet for Improving First-Pass Intubation Success

open

Jul 31, 2026$313,365 - $313,365

Patient-Oriented Research Mentoring for the Investigation of Acute and Chronic Sickle Cell Disease Pain

open

Jul 31, 2030$122,840 - $122,840

Exploring the role of Hedgehog pathway-Primary cilia axis in human lung alveologenesis and disease

open

Jul 31, 2027$156,168 - $156,168

The Gut Microbiome and Development of Acute Graft-Versus-Host Disease After Allogeneic Hematopoietic Cell Transplantation in Children

open

Jul 31, 2030$163,923 - $163,923

Characterize TMEM94 as ER Mg2+ uptake machinery and pathophysiological consequences.

open

Apr 30, 2029$586,516 - $586,516

Discerning L-type trafficking modulation by targeted excision of ubiquitin and SUMO

open

Jul 31, 2027$133,436 - $133,436

Triglyceride-rich lipoproteins and abdominal aortic aneurysm growth and progression

open

Jul 31, 2029$713,382 - $713,382

Defining the Mechanism of Complement Pathway Activation during Pregnancy and its Role in Adverse Pregnancy Outcomes in Sickle Cell Disease

open

Jul 31, 2030$197,259 - $197,259

Mechanistic Insights into Health Disparities: Leveraging Longitudinal Wearable Data to Assess the Impact of Built Environment on Physical Activity and Health Outcomes

open

Jul 31, 2027$42,941 - $42,941

Mesenchymal cell plasticity and signaling in lung regeneration

open

Jul 31, 2028$248,999 - $248,999

AI Driven End-to-End 4D flow MRI Pipeline for Hemodynamic Assessment in BAV Disease

open

May 31, 2030$704,234 - $704,234

Leveraging the mitochondrial regulator MIRO1 to prevent neointimal hyperplasia

open

Nov 30, 2026$482,748 - $482,748

The Role of S1PR2 in MRSA-induced Barrier Dysfunction and Lung Injury

open

Aug 4, 2027$75,520 - $75,520

Pressure Regulation of Vascular CaV1.2 Channels

open

May 31, 2029$733,371 - $733,371

Polypill strategy for the treatment of patients after acute coronary syndromes - A multicenter randomized controlled trial

open

Jul 31, 2030$730,276 - $730,276

Optimized development of novel leaflet biomaterials for replacement heart valves

open

May 31, 2029$1,356,922 - $1,356,922

Health system interventions for hypertension: evidence to inform policy in two Indian states

open

Aug 6, 2028$49,538 - $49,538

NATIONAL HEART, LUNG, AND BLOOD INSTITUTE (NHLBI) DIGITAL ASSET MANAGEMENT TOOL

open

Aug 6, 2026$41,809 - $41,809

How Centrioles Control Mammalian Development

open

May 31, 2029$568,177 - $568,177

Pathogenic mechanisms of chronic lung sequelae following respiratory viral infection

open

May 31, 2029$754,729 - $754,729

SONARQUBE ENTERPRISE EDITION

open

Aug 9, 2026$53,046 - $53,046

Origins of neonatal lung myofibroblasts

open

May 31, 2029$594,583 - $594,583

The Impact of Pulmonary Influenza Infection on the Pathogenesis of Myocardial Infarction and Heart Failure

open

Jul 31, 2027$167,940 - $167,940

COPD GENE - GENETIC EPIDEMIOLOGY OF COPD - TASK AREA A: YEAR 3 - AUGUST 10, 2025 - AUGUST 9, 2026

open

Aug 9, 2026$9,292,344 - $9,292,344

Bioprinting Tissue Engineered Vascular Conduits for Treating Single Ventricle Defects

open

May 31, 2027$460,625 - $460,625

Advancing Aortic Aneurysm Strength Predictions: A Novel Density-Driven Strength Assessment Tool

open

May 31, 2027$410,139 - $410,139

The role of matrifibrocytes in a fibrotic-like response during myxomatous heart valve disease progression

open

Jul 31, 2027$118,632 - $118,632

Pre-mRNA Processing and Function of Alternatively Spliced Isoforms of TFPI

open

Jul 31, 2028$249,000 - $249,000

Unraveling the mechanisms behind lymphatic dysfunction in obesity: are weight-loss drugs effective at restoring lymphatic function?

open

Aug 11, 2027$49,538 - $49,538

Personalized Risk Prediction and Mechanistic Profiling of Cardiac Allograft Vasculopathy

open

May 31, 2029$705,063 - $705,063

1/2 A Phase 2 Study of Elafin (Tiprelestat) for the Treatment of Pulmonary Arterial Hypertension (PAH)

open

Jul 31, 2026$1,998,124 - $1,998,124

The Desmosome-Keratin Intermediate Filament Network in Lung Epithelial Injury, Repair and Regeneration

open

May 31, 2029$722,584 - $722,584

Guideline-Recommended Implementation of Pediatric Ambulatory Blood Pressure Monitoring (GRIP ABPM)

open

Jul 31, 2030$194,722 - $194,722

Carotid Pulse Arrival Time as a Potential Biomarker for Ascending Thoracic Aortic Aneurysm: Proof-of-Concept Studies

open

Jul 31, 2027$389,748 - $389,748

Immunosuppressive Neutrophils Modulate Alloimmune Responses After Lung Transplantation

open

Jul 31, 2030$167,705 - $167,705

Nutrient Sensing of Apoptotic Cells by Macrophages Resolves Inflammation, Drives Atherosclerosis Regression, and Promotes Features of Plaque Instability

open

May 31, 2029$659,441 - $659,441

Continuous Positive Airway Pressure, Arousability and Links to Mechanisms in Obstructive Sleep Apnea (CALM-OSA).

open

May 31, 2030$764,853 - $764,853

Role of Protein S-Palmitoylation in TGFbeta Signaling and Fibrotic Lung Disease

open

Jun 30, 2030$165,456 - $165,456

Impact of Asymptomatic CMV on Cardiovascular Event Risk in Treated HIV

open

Jul 31, 2029$2,981,544 - $2,981,544

Sleep loss and circadian misalignment - mechanisms of Insulin Resistance

open

May 31, 2029$743,388 - $743,388

Incorporating Donor Lung CT Images into Machine Learning Models to Predict Severe Primary Graft Dysfunction after Lung Transplantation

open

May 31, 2029$782,289 - $782,289

Proteomic profiling for proteins associated with intracranial atherosclerotic disease.

open

Jul 31, 2030$158,910 - $158,910

Development of a versatile paired prime editing toolkit for CFTR gene correction

open

May 31, 2030$730,268 - $730,268

Endothelial protocadherins in vascular development and disease

open

May 31, 2029$775,720 - $775,720

Biological aging in early life: exploring developmental and environmental predictors of telomere length and impacts on subclinical atherosclerosis development

open

May 31, 2030$549,128 - $549,128

Epigenetic regulation of donor heart preservation mediated by Brd4

open

May 31, 2029$739,562 - $739,562

Major histocompatibility complex gene editing to prevent hematopoietic stem cell graft rejection

open

May 31, 2030$725,971 - $725,971

Aortic Disease-Associated SNPs Lead to Epigenetic Regulation Alterations That Increase Susceptibility to Aortic Aneurysm and Dissection

open

Jul 31, 2027$240,000 - $240,000

Mechanical regulation of cardiac growth and remodeling by VCAN-GPR126 signaling

open

May 31, 2029$744,692 - $744,692

Pulmonary vagal sensory neurons in chronic lung disease

open

May 31, 2030$497,628 - $497,628

Lymph Node Stromal Cells in the Pathogenesis, Diagnosis, and Treatment of Unicentric Castleman Disease

open

Jul 31, 2030$169,020 - $169,020

Validation of a CD206-targeted PET imaging probe for pulmonary fibrosis

open

Jul 31, 2027$247,500 - $247,500

Early Changes of T2* Measures in Lung Tissues using deltaTE-UTE MRI on healthy and COPD Patients

open

May 31, 2027$108,003 - $108,003

Developing vectors for potent and selective manipulation of cardiac rhythm

open

May 31, 2029$520,483 - $520,483

Role of Intraepithelial airway macrophages in lung homeostasis and disease

open

May 31, 2030$170,640 - $170,640

Interactions Between Genetics, Air Pollution, and Preschool-Onset Childhood Asthma

open

May 31, 2030$176,220 - $176,220

Tailored Treatment Strategies for Patients with Chronic Limb Threatening Ischemia

open

May 31, 2029$699,296 - $699,296

Natural language processing and machine learning for development of a Fontan Failure risk prediction model from electronic health records

open

Jul 31, 2027$232,498 - $232,498

NNMT Inhibition for treating heart failure

open

May 31, 2029$736,089 - $736,089

Optimizing Medications and Lung Health in People with HIV through Pharmacist-led Proactive E-Consults (OPTIMIZE Lung-HIV)

open

May 31, 2030$803,801 - $803,801

Identification of microproteins associated with hematopoiesis and related diseases

open

Jul 31, 2027$292,500 - $292,500

Research Software Engineering Support For The Simvascular Open-Source Project

open

May 31, 2028$154,000 - $154,000

iPRISM (Imaging-enhanced Prediction of RIsk for Sudden cardiac death in hcM)

open

May 31, 2029$1,289,113 - $1,289,113

Development of a Rapid and Non-Contrast Low-Field MRI-Based Assessment of Pulmonary Embolism

open

Jul 31, 2027$429,000 - $429,000

Determination of Persistent Inflammation, Immunosuppression, and Catabolism Syndrome in the Pediatric Cardiac ICU

open

Jul 31, 2027$271,938 - $271,938

Mechanisms of Junctional Proteins in Post-Surgical Lymphedema

open

May 31, 2030$414,996 - $414,996

Heterochromatin dynamics in vascular smooth muscle plasticity

open

Jun 30, 2029$756,224 - $756,224

Pericardial mRNA therapy for myocardial infarction

open

May 31, 2030$402,911 - $402,911

Develop an electromagnetic-actuated, dynamic cell culture method for airway epithelial cells

open

Jul 31, 2027$422,075 - $422,075

Proteolytic Regulation of Factor VIII Before and After Activation

open

May 31, 2030$636,982 - $636,982

HAT-Dependent Control of Cardiac Fibrosis

open

May 31, 2029$553,217 - $553,217

Inflammatory and Genetic Cardiomyopathies: Metabolic Phenotyping to Guide Diagnosis and Therapy

open

May 31, 2029$663,578 - $663,578

The Impact of SLC26A9 on Response to CFTR Correction

open

May 31, 2030$727,575 - $727,575

Dysfunctional Renin-Angiotensin System in Septic Shock

open

May 31, 2030$753,208 - $753,208

Development of integrated OCT/US/PAT system for intravascular Imaging

open

May 31, 2029$617,366 - $617,366

Advancing Techquity: Optimization of the FAITH! App for Dissemination to Promote Cardiovascular Health among African Americans

open

Jul 31, 2026$498,576 - $498,576

Modeling intra- and inter-cellular networks for TRPC6-dependent cardiac fibrosis

open

Apr 30, 2029$726,452 - $726,452

Eliminating Donor Availability Disparities in Hematopoietic Stem Cell Transplantation with AI-based Prediction of Permissive HLA Mismatches in the Context of Posttransplant Cyclophosphamide

open

Jul 31, 2026$207,740 - $207,740

Regenerative function of myeloid derived suppressor cells in the damaged bone marrow endothelial niche

open

May 31, 2029$461,132 - $461,132

Democratizing Access to Cleaner Residential Air (DACRA)

open

Jul 31, 2028$293,395 - $293,395

UC Davis StARR Training Program in Veterinary and Human Health

open

Jul 31, 2030$227,410 - $227,410

A Novel ENaC Blocker/Osmolyte Inhalation Solution for the Treatment of Muco-Obstructive Lung Diseases

open

Jul 31, 2026$1,971,749 - $1,971,749

Alveolar macrophage and epithelial cell lipid metabolism in pulmonary fibrosis

open

Jul 31, 2030$169,992 - $169,992

Intein technology to deliver CFTR to CF airway using AAV

open

Jul 31, 2027$441,375 - $441,375

Alk1 ligand requirements for AVM prevention in HHT

open

May 31, 2029$725,060 - $725,060

2/2 A Phase 2 Study of Elafin (Tiprelestat) for the Treatment of Pulmonary Arterial Hypertension (PAH)

open

Jul 31, 2030$936,858 - $936,858

Career Enhancement Core

open

Jul 31, 2030$284,357 - $284,357

Interplay of Inflammation, Angiogenesis, and Coronary Microvascular Perfusion in Advanced Kidney Disease

open

Jul 31, 2030$193,984 - $193,984

Decoding Force Transduction Mechanisms of Leukocyte Specific Integrin LFA-1 in Immune Responses

open

Jul 31, 2027$234,000 - $234,000

Modeling oxygen-dependent hemoglobin polymerization in sickle cell disease at the single cell level

open

May 31, 2029$719,128 - $719,128

Determining the regulatory role of microprotein ALN on SERCA2a and heart contractility

open

Jan 2, 2027$54,538 - $54,538

Putting Implementation into context to advance the management of mechanically ventilated patients.

open

May 31, 2029$748,970 - $748,970

Smad3-mediated gene-environment interaction and risk of tobacco-induced aneurysms

open

Jul 31, 2029$686,685 - $686,685

Implementation of streamlined, standardized blood pressure measurement protocols in primary care

open

Jul 31, 2030$162,703 - $162,703

Targeted mRNA therapies treating ARDS

open

Jul 31, 2028$249,000 - $249,000

Project 2: Smooth muscle cell programs for coronary artery disease

open

Jul 31, 2030$501,611 - $501,611

Optimizing HCT Outcomes: A Multi-omic Investigation

open

May 31, 2030$2,024,340 - $2,024,340

Editing basal cells for durable gene therapy of cystic fibrosis

open

May 31, 2029$564,121 - $564,121

Cardiovascular risk prediction from AI analysis of coronary calcifications

open

Aug 14, 2026$304,415 - $304,415

Transit-Oriented Development: Implications for Childhood Obesity and Asthma

open

Jul 31, 2030$174,829 - $174,829

Targeting Estrogenic pathways in Tregs to promote ARDS resolution - 5R01HL163881

open

May 31, 2026$684,280 - $684,280

Deciphering the novel regulatory mechanisms of neovascularization, cardiomyocyte survival, and endothelial cell-cardiomyocyte crosstalk in myocardial infarction

open

May 31, 2029$637,126 - $637,126

Zinc Supplementation in SCD: A Precursor to the Think Zinc for Bones Trial

open

Jul 31, 2027$449,538 - $449,538

Regionalization of Care for Acute Type A Aortic Dissection: Utilizing Mixed Methods Toward Bottom-Up Health System Interventions in Emergent Surgical Care

open

Aug 17, 2027$97,040 - $97,040

Programmed Cell Death 4 in Doxorubicin-Induced Cardiotoxicity

open

May 31, 2029$695,997 - $695,997

Stress-induced tRNA-derived small RNAs in cardiac fibrosis

open

May 31, 2030$739,474 - $739,474

Biological basis of cardiac thick filament regulation

open

May 31, 2029$715,378 - $715,378

Molecular mechanisms of polymodal TRP channels in regulation of microvascular endothelial function

open

May 31, 2029$708,108 - $708,108

A Yap to Notch Transcriptional Activity Transition Governs Postnatal Cardiomyocyte Maturation

open

Aug 17, 2028$75,052 - $75,052

Nanotherapeutic strategies for the treatment of chronic Chagas Disease

open

May 31, 2029$666,319 - $666,319

Hydrogen Sulfide and GLP-1 Combination Therapy to Treat HFpEF

open

May 31, 2029$759,206 - $759,206

Cardiac Effects of Mineralocorticoid Receptor Antagonism after Preeclampsia (CARDAMOM)

open

May 31, 2030$658,418 - $658,418

Cell type-specific roles of integrin CD11b in atherosclerosis regression

open

May 31, 2029$752,709 - $752,709

Mentored implementation science research in asthma

open

Jul 31, 2030$120,363 - $120,363

The Impact of Myosin-Binding Protein C on Myosin Mobility and Proteostasis.

open

May 31, 2029$713,511 - $713,511

Validation of a pediatric thrombosis risk assessment model and characterization of bleeding in hospitalized children through the Children's Hospital Acquired Thrombosis (CHAT) Consortium

open

Jul 31, 2027$70,096 - $70,096

Application of Modern Methods to Predict Risk and Estimate Treatment Effectiveness in Cardiogenic Shock

open

May 31, 2029$817,358 - $817,358

Antihypertensive self-titration to improve US blood pressure control

open

Jul 31, 2028$285,195 - $285,195

An intelligent clinical decision support system for peripheral arterial disease

open

May 31, 2030$175,049 - $175,049

Mechanisms and therapeutic potential of phrenic proprioceptors after spinal cord injury

open

May 31, 2030$569,695 - $569,695

Pulmonary Immune Regulation of Lung Injury after Pediatric Hematopoietic Cell Transplant

open

May 31, 2030$719,882 - $719,882

Tough Adhesive Sealants for Vascular Surgery

open

Jul 31, 2026$464,229 - $464,229

Regulation of disease progression by ER stress

open

May 31, 2029$663,730 - $663,730

Nuclear transport of developmental signaling effectors

open

May 31, 2029$630,169 - $630,169

Feasibility and Acceptability of A Mobile Application "SUPPORT-T" to increase access of Palliative Care in patients with Progressive Pulmonary Fibrosis (PPF) and their caregivers

open

Aug 31, 2027$355,530 - $355,530

Mechanosensitive mechanism of angiogenesis in the lung

open

May 31, 2029$618,838 - $618,838

Proteomic markers of early and late stage pulmonary fibrosis

open

May 31, 2030$644,997 - $644,997

Investigating Donor Authorization and Public Perceptions of Normothermic Regional Perfusion to Inform Ethical Organ Donation Practices

open

Feb 28, 2029$169,500 - $169,500

Mito-inflammation and sepsis-induced acute lung injury

open

May 31, 2029$694,398 - $694,398

The role of kynurenine pathway metabolism in pulmonary arterial hypertension

open

Jun 30, 2030$514,484 - $514,484

RASA3 is a Candidate Gene in the Pathogenesis of Pulmonary Arterial Hypertension

open

Jul 31, 2030$156,416 - $156,416

SMART-SEPSIS: Sequential MAchine learning for individualized Response to early Treatment in lung SEPSIS

open

May 31, 2029$750,561 - $750,561

Multi-modal dynamic risk prediction of thrombosis and bleeding in patients with cancer

open

May 31, 2030$721,826 - $721,826

Delivering Patient-Facing Evidence-Based Guidelines through mHealth to Adults with Sickle Cell Disease (PF-Guide)

open

Jul 31, 2030$765,931 - $765,931

VEGFR1 and its regulation by thrombin signaling during placental vascular growth

open

Apr 30, 2030$722,824 - $722,824

Developing Engagement Protocols for Donor Family Members and Healthcare Staff During Research Involving the Recently Deceased

open

May 31, 2030$762,747 - $762,747

Endothelin-1 signaling in microvascular responses to insulin and the role of physical activity and sedentary behavior in women with a history of gestational diabetes mellitus

open

Aug 21, 2028$38,363 - $38,363

Computational Models of Mechanical Thrombectomy in Acute Ischemic Stroke Treatment

open

Aug 24, 2028$41,266 - $41,266

Leveraging Informatics to Optimize Cardiovascular Risk Prediction in Women

open

Jul 31, 2028$185,760 - $185,760

Advanced body composition imaging to improve outcomes in lung transplantation

open

Apr 30, 2030$833,388 - $833,388

Renin as a Predictive and Prognostic Biomarker in Sepsis-Induced Hypotension

open

Jul 31, 2027$243,750 - $243,750

Endothelial Cell SR-BI Regulation and Novel Protein Partners in Atherosclerosis

open

May 31, 2029$772,275 - $772,275

The role of 12-lipoxygenase in regulating the effects of EPA on platelet activation and thrombosis

open

Aug 24, 2027$43,109 - $43,109

Amplifying the Impact of the Fresh Fruit and Vegetable Program Beyond Schools: A Multisectoral Approach

open

Jul 31, 2027$694,975 - $694,975

Harnessing Observational Data through Causal Inference to Reduce Hospital Readmissions for Survivors of Pneumonia with Respiratory Failure

open

Aug 25, 2026$101,360 - $101,360

INTEGRATE RX: Integrating Clinical Pharmacists in HIV care to Mitigate Last-Mile Challenges and Reduce Cardiovascular Disease Burden

open

Jul 31, 2030$312,005 - $312,005

Comparative study of gene regulatory and structural mechanisms in Lamin-related cardiomyopathy

open

May 31, 2029$511,987 - $511,987

Innovative implementation of artificial intelligence techniques for enhanced management of aortic abdominal aneurysms

open

Aug 30, 2028$75,520 - $75,520

Sex Specific Differences in the Remodeling of a Biopolymer Based Tissue Engineered Vascular Graft

open

Aug 31, 2027$49,538 - $49,538

Assembly and Localization of hERG Channel Cotranslational Complexes

open

Aug 31, 2026$75,520 - $75,520

Investigating the role of endothelial and fibroblastic reticular cells in lung inflammation caused by STING gain-of-function autoinflammation

open

Aug 31, 2028$37,577 - $37,577

Investigating the developmental programming of hematopoietic stem and progenitor cells

open

Aug 31, 2027$37,898 - $37,898

The Utility of Advanced Unsupervised Learning Methods to Model Dietary Intake Data

open

Feb 28, 2027$49,138 - $49,138

Measuring demographic variables across groups to understand cardiovascular health among US adults

open

Aug 31, 2027$229,245 - $229,245

Regulatory T Cells And Bronchopulmonary Dysplasia-Associated Pulmonary Hypertension

open

Jun 30, 2030$773,868 - $773,868

Metabolic Adaptations to Acute and Chronic Exercise

open

Aug 31, 2028$349,728 - $349,728

Targeting protein phosphatase 2A for takotsubo syndrome treatment

open

Jun 30, 2029$709,081 - $709,081

Cell-Type Specific Mechanisms of Mitral Valve Prolapse

open

Aug 31, 2029$3,008,247 - $3,008,247

Uncovering Cross-Disease Platelet Transcriptomic Signatures to Advance Precision Medicine

open

Aug 31, 2027$235,500 - $235,500

Integrating Generative AI with Biomechanics Modeling to Advance Ventricular Disease Diagnosis and Personalized Treatment

open

Aug 31, 2028$522,695 - $522,695

Role of hexokinase 3 in macrophage polarization and cardiac remodeling after myocardial infraction.

open

Jun 30, 2029$676,459 - $676,459

Depict the cell fate map of pulmonary angioblast

open

Aug 31, 2027$226,101 - $226,101

Novel Roles for IRE1 in Regulating Cardiac Fibrosis

open

Jun 30, 2029$745,663 - $745,663

Wireless implantable cardiac systems for continuous multiparametric investigation of cardiac arrhythmias in vivo

open

May 31, 2029$664,432 - $664,432

ZEB1 Mediated Coronary Artery Disease Risk in Vascular Smooth Muscle

open

Aug 31, 2030$165,888 - $165,888

Detecting Growth of Intracranial Aneurysms Using Non-Invasive Photon Counting CT in a Murine Model.

open

Jun 30, 2029$776,129 - $776,129

Quantifying Uncertainty to Inform Time-Limited Trials of Invasive Mechanical Ventilation

open

May 31, 2030$761,599 - $761,599

Novel mechanistic insights of inflammation and organ injury

open

May 31, 2029$245,250 - $245,250

The role of lipid metabolism in lung macrophage activity and phenotypes during acute lung injury

open

Aug 31, 2027$233,250 - $233,250

Ex Vivo Storage, Preservation And Rehabilitation Of Living Heart Valves For Allogenic Valve Transplantation

open

May 31, 2030$709,718 - $709,718

Improving mutant KV11.1 trafficking to treat Long QT Syndrome

open

Aug 31, 2030$131,571 - $131,571

Regulation of endothelial function and vascular integrity by neddylation

open

Jun 30, 2029$701,791 - $701,791

Interrupting pro-inflammatory pulmonary-vascular cell interactions to reduce pulmonary capillary leak in critically ill children with bronchiolitis

open

May 31, 2029$958,850 - $958,850

Chemokine receptor signaling and the dynamics of neutrophil phenotypes during inflammatory lung injury

open

Jun 30, 2029$796,189 - $796,189

An electronic health record-based strategy to optimize blood pressure among pregnancy-capable adults in primary care: The REACH-OUT Trial

open

Jun 30, 2030$661,129 - $661,129

YAP and TAZ regulate alveolar epithelial cell regeneration during lung repair

open

Aug 31, 2030$811,370 - $811,370

Detection and quantification of amyloidosis deposition and circulating amyloid fibrils in asymptomatic carriers of the V122I TTR allele

open

May 31, 2029$691,556 - $691,556

Coagulations 'Drake Passage': The Bumpy Transition Between Fibrinogen and Fibrin

open

Aug 31, 2028$558,697 - $558,697

Indole Metabolites as Xenobiotic Danger signals in Acute Lung Injury

open

May 31, 2029$688,163 - $688,163

Addressing differential performance by socioeconomic status in Artificial Intelligence (AI) models for childhood asthma

open

Jun 30, 2029$526,890 - $526,890

Using machine learning to understand cardiopulmonary and renal end organ complications for individuals with SCD

open

Jun 30, 2029$146,013 - $146,013

The Effect of Hyperoxia on Neonatal Respiratory Progenitor Cell Function

open

Aug 31, 2030$166,395 - $166,395

AAV therapies for TNNT2-associated cardiac disorders

open

Jul 31, 2027$611,014 - $611,014

Commercialization of the Head Up CPR System for Improving Survival after Cardiac Arrest

open

Aug 31, 2026$498,453 - $498,453

Proton and hyperpolarized xenon pulmonary MRI at 0.55T

open

Jun 30, 2029$659,644 - $659,644

Pediatric Cardiorespiratory Research Training Program: Childhood origins of diseases across the lifespan.

open

Aug 31, 2030$430,606 - $430,606

Biochemical Silencing of Maladaptive Inflammation in Heart Failure

open

Aug 31, 2027$36,526 - $36,526

Fractionation of RBCs via label-free magnetophoresis using novel additive-manufactured devices

open

Aug 31, 2028$587,878 - $587,878

Menopausal hormone therapy, the gut microbiome, and estrogen-related outcomes in women with HIV

open

Aug 31, 2027$252,000 - $252,000

2025 Sex Differences & Women’s Health Research Conference

open

Aug 31, 2026$12,000 - $12,000

Understanding Early Drivers and Therapeutic Targets for Severe Forms of Arrhythmogenic Cardiomyopathy

open

Jun 30, 2029$727,710 - $727,710

Role of the SFTA2/ADGRF5 signaling axis in alveolar homeostasis

open

Jun 30, 2029$702,103 - $702,103

Impact of Pregnancy Microbiomes on Maternal and Child Cardiovascular Health in a Racially and Ethnically Diverse Cohort

open

May 31, 2030$720,399 - $720,399

Leveraging research and clinical cohorts to improve Obstructive Sleep Apnea subtyping

open

May 31, 2029$818,279 - $818,279

Magnetoelastic Vascular Grafts

open

Jun 30, 2029$534,761 - $534,761

Human pulmonary neuroendocrine progenitors in lung injury and disease

open

Jun 30, 2029$761,017 - $761,017

Hypertension Scientific Sessions 2025

open

Aug 31, 2026$15,000 - $15,000

Stratifying thrombosis risk in Kawasaki Disease using hemodynamic analysis beyond the z-score

open

Aug 31, 2028$410,956 - $410,956

Probing Regional Metabolism During Exercise through Coronary Sinus Sampling

open

Aug 31, 2027$242,250 - $242,250

Glycan-Mediated Impacts on the Mucus Barrier Towards Respiratory Viruses

open

Jun 30, 2029$711,144 - $711,144

Epimetabolic regulation of macrophage activation in the intra-alveolar compartment during acute lung injury

open

May 31, 2029$744,880 - $744,880

Sweet receptor T1R3 in airway glucose homeostasis and chronic rhinosinusitis

open

May 31, 2029$506,420 - $506,420

Neural effects of breathing training in obstructive sleep apnea

open

Jun 30, 2029$721,237 - $721,237

Development of a Small, Durable, Hemocompatible Centrifugal Blood Pump for Children

open

Jun 30, 2029$784,203 - $784,203

Association between blood biomarkers and adverse cardiovascular and kidney outcomes

open

Aug 31, 2027$237,750 - $237,750

Function and Regulation of Airway Mucin Glycosylation

open

Jun 30, 2029$702,308 - $702,308

Impact of respiratory muscle training and nitrate therapy on exercise tolerance in hypoxia

open

Aug 31, 2028$538,125 - $538,125

Mechanistic Contribution of Internal Circadian Misalignment to the Cardiometabolic Risk of Sleep Loss

open

May 31, 2030$730,993 - $730,993

Menopause-related Vasomotor Symptoms and Cardiovascular Health

open

May 31, 2030$788,301 - $788,301

Examining the crossover effects of adolescent stress on parent cardiovascular health

open

May 31, 2030$696,945 - $696,945

Shaping Cardiac Immuno-metabolic Homeostasis by the Lysosome

open

May 31, 2029$612,186 - $612,186

Intravenously injected mesenchymal stromal cells protect against Acute Lung Injury by transferring mitochondria to restore endothelial function

open

Jun 30, 2029$761,262 - $761,262

Neural Mechanisms of Premature Ventricular Contraction-Induced Cardiomyopathy Revealed by Targeted Neuromodulation of the Cardiac Neuraxis

open

May 31, 2030$472,511 - $472,511

Vascular Regeneration with Reprogrammed Endothelial Cells

open

Aug 31, 2026$306,607 - $306,607

iPediHeart: Interdisciplinary Research Training Program for Pediatric Heart Disease

open

Aug 31, 2030$200,938 - $200,938

Maternal Obstetric Monitoring System (MOMS): a Postpartum Hemorrhage (PPH) Wearable Monitor

open

Jul 31, 2026$392,500 - $392,500

Drug Coated Balloon Peptide Delivery to Block Post-angioplasty Restenosis in PAD

open

Jul 31, 2027$489,644 - $489,644

Investigating the impact of donor and environmental age on iPSC derived endothelial progenitors

open

Aug 31, 2027$44,266 - $44,266

Understanding the Efficacy of T-TEER in Models of Primary Tricuspid Regurgitation

open

Aug 31, 2028$41,266 - $41,266

Advanced CV imaging and immunophenotyping to study coronary vascular health in psoriasis

open

Aug 31, 2026$194,400 - $194,400

Developing Implementation Science Expertise in Cardiovascular Health Services Research

open

Jul 31, 2030$133,085 - $133,085

Sphingosine kinase 1 plays a key role in defective elastin-induced arterial hypermuscularization

open

Aug 31, 2028$249,000 - $249,000

Molecular and Cellular Mechanisms of the Aberrant Type I Interferon Response in VEXAS Syndrome

open

Aug 31, 2028$49,538 - $49,538

Synthetic morphogenesis to recapitulate multicellular patterns for regenerative medicine

open

Aug 31, 2027$166,752 - $166,752

Development of an automatic real-time personalized non-invasive localization of the site of origin of the earliest ventricular activation

open

Aug 31, 2026$90,789 - $90,789

How Endothelial Tetraspanins Inhibit Inflammation

open

Aug 31, 2027$729,981 - $729,981

Understanding the Nature and Regulation of Extramedullary Hematopoiesis in the Liver

open

Aug 31, 2028$248,999 - $248,999

Cardiac Sensory and Sympathetic Nerve Dysregulation in Hypertrophic Cardiomyopathy

open

Aug 31, 2028$589,998 - $589,998

Klf2/4 and mechanical signaling in cardiac fibroblasts

open

Aug 31, 2030$165,366 - $165,366

Cellular and molecular determinants of an injury-associated capillary endothelial cell state during acute lung injury and regeneration

open

Aug 31, 2030$169,020 - $169,020

The dynamic role of the alveolar macrophage during pulmonary bacterial infection

open

Aug 31, 2030$161,890 - $161,890

Casein Kinase 2 at the Intersection of Beta2-adrenoceptor Signaling and cAMP Egress

open

Aug 31, 2027$46,025 - $46,025

Role of KLF6 in Lung Development

open

Aug 31, 2028$173,259 - $173,259

Epigenomic Dynamics of Clonal Hematopoiesis

open

Aug 31, 2027$44,945 - $44,945

Reverse translational multi-omics to identify treatment targets for atrial myopathy

open

Aug 31, 2030$174,528 - $174,528

The effect of body composition on patient-centered outcomes in advanced interstitial lung disease

open

Aug 31, 2028$89,860 - $89,860

Myeloid cell ferroptosis in hemorrhagic stroke

open

Aug 31, 2027$78,040 - $78,040

Championing Heart Health: Preventing the Leading Cause of Death - National Forum Annual Meeting 2025

open

Aug 31, 2026$5,000 - $5,000

Dying While Poor: Investigating Multi-level Determinants of Inequities in End-of-life Care for Adults with Heart Failure

open

Aug 31, 2029$142,870 - $142,870

Characterization of the role of STK38 kinase in Wnt signaling and heart development

open

Aug 31, 2028$34,954 - $34,954

REACH BP: REmote physical ACtivity intervention for High Blood Pressure Postpartum

open

Aug 31, 2030$192,199 - $192,199

Volume And Patient-Oriented Research in Chronic Kidney Disease (VAPOR-CKD)

open

Aug 31, 2030$131,886 - $131,886

Excess cardiovascular inflammation in TB and HIV: EXFIN-TB

open

Aug 31, 2029$2,513,201 - $2,513,201

Mentored Patient-Oriented Research in Natriuretic Peptide System Based Precision Cardiometabolic Health

open

Aug 31, 2030$132,623 - $132,623

Role of Tbc1d2b in vessel formation and neovascularization after ischemic injury

open

Jun 30, 2029$720,526 - $720,526

Mechanistic re-evaluation of fibroblast growth factor homologous factors in the heart

open

Jun 30, 2029$708,265 - $708,265

Decoupling mitral valve-left ventricular fibrotic remodeling in degenerative mitral regurgitation via serotonin 2B receptor

open

May 31, 2029$759,030 - $759,030

Tissue transglutaminase as a therapeutic target for arterial stiffening and hypertension in obesity

open

May 31, 2029$685,654 - $685,654

Criteria for Retriage to Improve Trauma Induced Coagulopathy and hemorrhage Associated Lethality

open

Jun 30, 2029$783,715 - $783,715

19th International Conference on Endothelin: From New Discoveries to New Treatments

open

Aug 31, 2026$5,000 - $5,000

Vascular Proliferative Resilience

open

May 31, 2029$748,965 - $748,965

Don S. Fredrickson Lipid Research Conference

open

Aug 31, 2026$10,000 - $10,000

Ribosome Dysfunction in Lung Fibrosis

open

May 31, 2030$722,667 - $722,667

Tulane Essentials in Internal Medicine Symposium

open

Aug 31, 2026$5,000 - $5,000

Expandable Pediatric Pulmonary Heart Valve

open

Aug 31, 2027$321,679 - $321,679

An Integrated microbiota-gut-brain axis model for Hypertension Signaling

open

Aug 31, 2027$399,174 - $399,174

Lipid Mediators: Advancements and Approaches

open

Aug 31, 2026$5,000 - $5,000

C type Lectin Pathway Regulates Macrophage Immune Metabolism in Mtb-Infected Lung

open

Jun 30, 2029$788,478 - $788,478

Elucidating Anthracycline-Induced Cell Type-Specific Cardiovascular Toxicity with CRISPRi/a Screens

open

Aug 31, 2030$769,543 - $769,543

Selective Targeting of Alveolar Capillaries in Neonatal Lung Injury

open

May 31, 2029$730,070 - $730,070

30-Year Follow-up of the Coronary Artery Calcium Consortium

open

Aug 31, 2027$232,500 - $232,500

Investigating the Impact of Selective Vagal Neuromodulation on Heart Failure Indices

open

Aug 31, 2027$429,000 - $429,000

Roles for SGK1 in Cardiometabolic Heart Failure with Preserved Ejection Fraction

open

Jul 31, 2029$654,530 - $654,530

Directly measured skin pigmentation to mitigate pulse oximetry bias

open

Aug 31, 2027$234,000 - $234,000

Promoting resilience and mechanisms underlying emotion and cardiovascular health as a function of adolescent social stress

open

Aug 31, 2028$380,000 - $380,000

Mathematical Modelling of Peripheral Metabolic Circadian Rhythms: Implications for Shift Work and Jetlag Management

open

Aug 31, 2027$281,560 - $281,560

Stress Regulated RNA Degradation in Cardiac Hypertrophy

open

May 31, 2030$698,432 - $698,432

Adding Inspiratory Muscle Training to Optimize Cardiac Rehabilitation for Heart Failure

open

Aug 31, 2030$745,851 - $745,851

Creating an Interactive Computer Model of Left Atrium Electrophysiology to Study the Underlying Mechanisms Leading to Atrial Fibrillation

open

Aug 31, 2028$464,502 - $464,502

Beyond BMI: Role of Body Composition, Coronary Microvascular Dysfunction and HFpEF in Characterizing Cardiometabolic Disease Phenotypes

open

May 31, 2030$784,362 - $784,362

Characterization of lung interstitial neutrophils

open

May 31, 2029$710,302 - $710,302

Brain MC4R-BAT-Heart crosstalk: a potential new therapeutic target for myocardial ischemia/reperfusion injury

open

Jun 30, 2030$540,927 - $540,927

Behavioral Science Strategies to Increase Hypertension Diagnosis and Treatment

open

Jun 30, 2030$597,719 - $597,719

Vascular Biology 2025

open

Aug 31, 2026$40,000 - $40,000

Disequilibrium in immune homeostasis in hypoxic pulmonary hypertension pathogenesis

open

Aug 31, 2027$1,286,637 - $1,286,637

Targeting PCBP1 to Ameliorate Pathological Angiogenesis

open

Jun 30, 2030$790,498 - $790,498

Preventing major amputations and preserving functional limbs in no option critical limb-threating ischemia patients

open

Aug 31, 2027$1,032,585 - $1,032,585

The effect of SPecialty cAre on Recovery from Cardiac arrest (the SPARC trial)

open

Aug 31, 2026$2,394,542 - $2,394,542

2/2 WIN Ratio Analysis to Determine a Strategy of Non-Invasive SUpport for Respiratory Failure in the EmeRgency Department (WINDSURFER)

open

Aug 31, 2031$688,047 - $688,047

Training Program in Patient-Oriented Research in Cardiovascular Endocrinology

open

Aug 31, 2030$201,426 - $201,426

The Post-Lung Transplant Impact of Alveolar Macrophage Senescence in Aged Donor Lungs

open

Aug 31, 2030$158,652 - $158,652

Circadian Regulation of Epithelial Immune Reponses in Asthma

open

Aug 31, 2030$154,980 - $154,980

Investigating the protective role of stress granules in cardiomyocytes

open

Aug 31, 2028$49,538 - $49,538

Carbonic Anhydrase Mediated Regulation of Microtubule Dynamics and Infection in Cystic Fibrosis

open

Aug 31, 2030$163,080 - $163,080

Discovery and characterization of programmable biological systems

open

Aug 31, 2028$1,485,000 - $1,485,000

Deciphering the role of regulatory T cell derived Mmp12 in lung injury resolution

open

Aug 31, 2028$39,023 - $39,023

Regulation of Atherosclerosis by Matrikine Endotrophin

open

Oct 31, 2027$36,673 - $36,673

CMYA5 modulates ryanodine receptor 2 (RYR2) activity in cardiomyocytes

open

Aug 31, 2028$85,744 - $85,744

ENT-based Approach to Cervical Phrenic Nerve Stimulation for the Treatment of Central Sleep Apnea

open

Aug 31, 2027$982,086 - $982,086

SMII activity drives VSMC phenotype

open

Aug 31, 2029$39,480 - $39,480

Thermoneutral Housing Protects from Fibrosis in IL-10 dependent manner

open

Aug 31, 2028$49,538 - $49,538

The role of TGF-β signaling in cell-cell interactions in the pathogenesis of lymphangioleiomyomatosis

open

Aug 31, 2028$39,140 - $39,140

Understanding hematopoietic stem and progenitor cell diversity during ontogeny

open

Aug 31, 2028$49,538 - $49,538

Enhancing Drug Screening with Automated Single-Cell Electrophysiology and Contractility Measurements in iPSC-CMs

open

Jul 31, 2027$398,820 - $398,820

Development of Novel RhoA Nitration Inhibitory Peptides for the Treatment of Acute Lung Injury

open

Jul 31, 2027$516,250 - $516,250

T-helper 2-low pediatric asthma endotypes: omics, biomarkers, and clinical characteristics

open

Jun 30, 2030$161,935 - $161,935

Electromechanically monitored engineered heart tissue platform

open

Aug 31, 2026$525,824 - $525,824

Cardiovascular Science Training Program (CSTP)

open

Aug 31, 2030$447,977 - $447,977

Designing and Piloting a Community-Based Intervention to Reduce Wildfire Smoke Exposure in Children with Asthma

open

Aug 31, 2029$160,380 - $160,380

IntelliStent: A minimally Invasive, Adjustable Pulmonary Flow Restrictor System for Congenital and Acquired Heart Disease

open

Aug 31, 2027$1,771,084 - $1,771,084

A population-based study of deep learning measures of breast arterial calcification for improving women's health using repurposed mammogram images

open

Jun 30, 2029$756,906 - $756,906

A transcatheter manufacturing toolkit for minimally-invasive and patient-specific device-based stroke prevention

open

Jul 31, 2027$397,034 - $397,034

Electrocardiographic Detection of Non-ST Elevation Myocardial Events for Accelerated Classification of Chest Pain Encounters (ECG-SMART 2)

open

Jun 30, 2027$19,836 - $19,836

Investigating the roles of VEGFR1 in angiogenesis of the allantois and placenta

open

Aug 31, 2028$54,538 - $54,538

Elucidating the Role of IL-1B Signaling in Shaping the Cardiac Immune Landscape After Injury

open

Aug 31, 2029$36,673 - $36,673

Understanding how appropriate apoptotic cell degradation ensures lung homeostasis

open

Aug 31, 2028$49,538 - $49,538

Deep Learning 4D flow MR Pipeline for the Automated Assessment of Aortic Hemodynamics in BAV

open

Aug 31, 2027$45,629 - $45,629

Mechanisms of Hematopoietic Stem Cell Reprogramming by Type II Interferon

open

Aug 31, 2029$54,538 - $54,538

Left-Right Organizer Cellular and Molecular Dynamics Drive Early Cardiac Asymmetries

open

Aug 31, 2028$49,538 - $49,538

Nationwide examination of access to comprehensive care in sickle cell disease

open

Aug 31, 2026$85,744 - $85,744

Developing models of placenta-driven developmental lung injury in human preeclampsia

open

Aug 31, 2030$166,752 - $166,752

Rare Bronchiectatic Diseases Consortium

open

May 31, 2030$50,819 - $50,819

Cross-Ancestry Comparison of Aptamer and Antibody Proteomics Measures

open

Aug 31, 2028$40,752 - $40,752

Dysregulation of transcription factors and chromatin architecture in Trisomy 21 hematopoietic disorders

open

Jun 30, 2030$158,976 - $158,976

Sex Differences in Cardiac Macrophages in Response to Pulmonary Hypertension

open

Aug 31, 2030$163,145 - $163,145

Modeling red blood cell metabolism in health and disease

open

Aug 31, 2028$38,702 - $38,702

Creation of the Framingham Heart Study Cardiovascular Biobank and Atlas

open

Jun 30, 2030$1,466,449 - $1,466,449

Leveraging Stored Platelet Bioenergetics to Improve Hemostatic Function Upon Transfusion

open

May 31, 2029$375,306 - $375,306

Integrating Hypertension and Cardiovascular Disease Care into Existing HIV Service Package in Botswana (InterCARE)-Statin Sub-study

open

Jun 30, 2030$462,277 - $462,277

Detrimental Effects of B-Cell-Th17 Axis in Antiviral Immunity in Smokers.

open

May 31, 2030$799,998 - $799,998

Immuno-cardiology 2025 Symposium

open

Aug 31, 2026$25,000 - $25,000

SCH: SciML-Accelerated Cardiovascular Digital Twins for Personalizing Long-Term Heart Valve Interventions

open

Aug 31, 2029$1,182,618 - $1,182,618

3D Printed Airway Splints: Pre-clinical and Clinical In Vivo Degradation and Tissue Response

open

Jun 30, 2030$709,172 - $709,172

Defining cardinal functions of lung progenitors during regeneration

open

Jun 30, 2029$701,795 - $701,795

Immune Activation and Region-specific Myocardial Arrhythmic Substrate in Sudden Cardiac Death Victims with HIV

open

Aug 31, 2029$3,264,423 - $3,264,423

The responsiveness of ILC2s in allergic airway inflammation

open

Jun 30, 2029$522,990 - $522,990

A novel shift-level approach to optimizing ICU interprofessional team composition for mechanically ventilated adults

open

Aug 31, 2027$272,226 - $272,226

Functional Response Biomarkers for Systemic Sclerosis-Associated Interstitial Lung Disease

open

Jun 30, 2030$693,558 - $693,558

Early, non-invasive detection of pulmonary vascular dysfunction in acute respiratory distress syndrome

open

Aug 31, 2027$247,500 - $247,500

Psychosocial and cultural determinants of cardiometabolic health among older Chinese Americans

open

Jul 31, 2029$721,720 - $721,720

Loss of Cilia Maintenance in Acquired and Genetic Lung Diseases

open

Jul 31, 2029$761,782 - $761,782

The Role of Perivascular Adipose Tissue in Atherosclerotic Cardiovascular Disease (PVAT-ASCVD)

open

Jun 30, 2030$762,969 - $762,969

Investigating Intimate Partner Violence in the Context of Sleep Among Survivors

open

Jun 30, 2027$198,750 - $198,750

Regulating Cellular Metabolism and Energy Flow to Target Thrombosis

open

Jun 30, 2029$713,538 - $713,538

Optimizing Cardiovascular Care and Promoting Excellent Health Outcomes for Adults with Diabetes across settings

open

Jun 30, 2030$763,858 - $763,858

Functional assessment of atrial myosin mutations in familial atrial arrhythmia

open

Aug 31, 2027$231,000 - $231,000

Mechanisms of Oxygen Toxicity

open

Jun 30, 2030$731,827 - $731,827

Time to ROSC as a Novel Outcome for Pediatric Cardiac Arrest Trials

open

Aug 31, 2027$279,644 - $279,644

Transbronchial diagnosis and characterization of pulmonary hypertension with Mechanomicroscopy

open

Jun 30, 2029$759,658 - $759,658

Probing human HSC genesis in a flow-directed 3D hemogenic vascular niche model

open

May 31, 2029$776,511 - $776,511

Platelet function abnormalities underlying bleeding in a connective tissue disorder the Ehlers Danlos syndrome

open

May 31, 2029$660,681 - $660,681

Improving prediction of persistent hypoxemic respiratory failure to support clinical trial enrichment

open

Aug 31, 2030$186,408 - $186,408

Intubation with Sedation Only to Prevent Hypoxemia during Emergency Tracheal Intubation of Critically Ill Adults: A Randomized Clinical Trial

open

Aug 31, 2030$185,720 - $185,720

The molecular determinants of atrial fibrillation

open

Aug 31, 2028$249,000 - $249,000

An Athero-Protective Pathway Mediated by Macrophage Tryptophan Metabolism and AhR Activation

open

Aug 31, 2027$167,400 - $167,400

Inter-organelle communication in lipid metabolism

open

May 31, 2029$548,816 - $548,816

Tracheal occlusion and nuclear YAP activation in the congenital diaphragmatic hernia fetal lung

open

Sep 1, 2027$84,724 - $84,724

Role of inflammation in postoperative atrial fibrillation

open

May 31, 2030$752,618 - $752,618

High speed and wearable speckle contrast optical spectroscopy for cuffless blood pressure measurements

open

May 31, 2029$649,678 - $649,678

Dysregulation of sphingolipid metabolism and signaling in LAM

open

May 31, 2029$728,776 - $728,776

Molecular basis of mitochondrial calcium extrusion - a key target in ischemic heart disease

open

Sep 1, 2027$49,538 - $49,538

Dissecting the Role of Mechanical Forces in the Branching Morphogenesis of the Mouse Bronchial Tree

open

Sep 2, 2027$33,538 - $33,538

Investigating The Role of Hippo Signaling in Sinoatrial Node Development

open

Sep 2, 2030$37,613 - $37,613

Implementation and effectiveness of a multi-sectoral promotores de salud intervention in rural Oregon's summer meal program to promote health quality of life among Latine families

open

Jul 31, 2027$744,997 - $744,997

Optimizing Maternal Health: Assessing Sleep-Based Strategy Enhancement of Diet, Physical Activity and Self-Regulation Interventions in Perinatal Health

open

Jun 30, 2029$616,864 - $616,864

Demonstrating the Feasibility of Democratized Push-Button Autonomous Cardiac MRI exam in Community Family Health Centers (AutoCMR for FHC)

open

May 31, 2029$783,801 - $783,801

Cardiovascular and respiratory responses to physical activity and heat stress in burn survivors

open

Sep 3, 2028$75,052 - $75,052

Role of Integrase Strand Transfer Inhibitors on Hypertension in People with HIV

open

Aug 31, 2027$223,438 - $223,438

Maternal Heart Health Starts at Home (MomHeart): Targeting Place-Based Social Determinants to Improve Pregnancy and Postpartum Cardiovascular

open

May 31, 2028$648,124 - $648,124

Effects of operational naps on blood pressure and performance among night shift workers

open

Aug 31, 2026$790,584 - $790,584

Development and Validation of Correction Equations to Enhance Quality of Infrared Technology

open

May 31, 2030$584,575 - $584,575

Regulation of thin filament architecture by CAP2 in health and myopathy

open

Jun 30, 2029$713,421 - $713,421

Mechanisms Contributing to Functional Recovery across the Care Cascade for Respiratory Failure

open

Sep 2, 2027$49,538 - $49,538

Regulation of Mitophagy by RNA Alternative Splicing in the Aging Heart

open

Aug 3, 2027$83,224 - $83,224

CHERISH (duCHennE caRdiomyopathy mItigation Sglt2 inHibitor)

open

Aug 31, 2027$444,838 - $444,838

Investigating the mechanisms of polycomb group protein mediated fetal hemoglobin silencing

open

Sep 3, 2029$54,538 - $54,538

Lysosomal ionic dysregulation in heart disease

open

Jun 30, 2030$717,558 - $717,558

AI-Enabled ComPLETE Model for Better Prediction of CLTIRevascularization Outcomes

open

Jun 30, 2030$756,228 - $756,228

Development of Mirror-Image Natural Products as Antiarrhythmic Therapeutics

open

May 31, 2029$744,145 - $744,145

Biomaterials for Cardiac Regeneration

open

Sep 4, 2027$80,020 - $80,020

CHAMPION Fathers: Cardiovascular Health AssessMent and Primary Care CoordinatION for Fathers

open

Aug 31, 2030$190,080 - $190,080

Interrogation of Genetic and Nutritional Control of Sleep across Seasons

open

Jun 30, 2027$134,982 - $134,982

2/2 Women's Aneurysm Research: Repair Immediately Or Routine Surveillance: WARRIORS trial

open

Aug 31, 2032$318,167 - $318,167

The 2025 LAM Foundation International Lymphangioleiomyomatosis Research Conference

open

Aug 31, 2026$30,000 - $30,000

Parsing molecular determinants of asymmetry in planar cell polarity signaling

open

Sep 4, 2027$49,538 - $49,538

Circadian Mechanisms Governing Cardiac Growth

open

Jun 30, 2029$539,342 - $539,342

Pragmatic trial of midodrine as a vasopressor-sparing agent in septic shock

open

Aug 31, 2026$783,661 - $783,661

Carbonic Anhydrase as a Cardioprotective Target in Anthracycline-induced Cardiotoxicity

open

May 31, 2030$552,318 - $552,318

Multi orientation Quantitative Susceptibility Mapping for Accurate Quantification of Iron in Hemorrhagic Myocardial Infarction

open

Jun 30, 2029$757,555 - $757,555

Development of Deep Learning Tools for Widely-Available, Inexpensive Diagnosis of Coronary Microvascular and Vasomotor Dysfunction

open

Aug 31, 2027$1,107,749 - $1,107,749

Effects of HIV Pre-Exposure Prophylaxis (PrEP) on Cardiovascular-Kidney-Metabolic Health and Risk for Cardiovascular Disease

open

Jun 30, 2029$743,492 - $743,492

Mechanistic diversity in biased angiotensin receptor ligands

open

May 31, 2029$512,815 - $512,815

The Role of Local Sleep Disturbance in Obesity Risk: A Sleep Neuroimaging Study

open

Aug 31, 2028$568,125 - $568,125

Functional Immune Phenotyping of Sepsis Patients: Integrating Microphysiological Assays, Omics and In Silico Modeling

open

Jun 30, 2029$683,299 - $683,299

The impact of Left Ventricular Assist Device Implantation on Cerebral Hemodynamics and Cognition

open

Jul 31, 2029$769,994 - $769,994

Development of a Mobile Health Intervention for Blood Pressure Management in Pregnancy

open

Aug 31, 2026$75,593 - $75,593

Integration of platelets and coagulation to maintain hemostasis in vivo

open

May 31, 2029$457,514 - $457,514

PASSPORT: PASsive Sensing to Prevent stress-related Overeating in Real-Time

open

Jun 30, 2030$723,305 - $723,305

Co-Developing a Stress Management Intervention for Black Adults with Hypertension

open

Aug 31, 2030$169,444 - $169,444

DIGITAL INCENTIVE SPIROMETRY EXERCISER TO IMPROVE PATIENT ADHERENCE AND CLINICAL WORKFLOWS

open

Sep 4, 2026$306,872 - $306,872

Unsupervised Machine Learning to Identify Unique Clusters of Systemic Sclerosis Pulmonary Hypertension Patients

open

Aug 31, 2027$245,624 - $245,624

Protein Translation for Oxidative Stress Response in Heart Failure

open

Aug 31, 2028$576,786 - $576,786

Efficacy of Hypoxic Red Blood Cells Processed with the Hemanext ONE® System in Patients with Sickle Cell Anemia

open

Aug 31, 2028$1,017,232 - $1,017,232

Role of Cardiac Proteoform Alterations in the Pathogenesis of Phospholamban R14del Cardiomyopathy

open

Sep 4, 2027$37,898 - $37,898

Integrating multi-omics data to understand the heterogeneity of preeclampsia and long-termpostpartum hypertension

open

Jun 30, 2030$524,179 - $524,179

BRING-IT: Biomedical Research Investing in Growth and ISU Talent

open

Aug 31, 2028$277,298 - $277,298

Deciphering Statin-Induced Muscle Symptoms: Mechanisms and Therapeutic Insights

open

May 31, 2030$654,388 - $654,388

Graft Stiffness as a Substrate for Adverse Cardiovascular Remodeling and Clinical Outcomes in Genetically Triggered Aortic Aneurysms

open

Aug 31, 2030$174,389 - $174,389

1/2 Women's Aneurysm Research: Repair Immediately Or Routine Surveillance: WARRIORS trial

open

Aug 31, 2026$1,196,948 - $1,196,948

Role of a Novel Hormone Complex, Fabkin, in Dyslipidemia and Inflammation in Atherosclerosis

open

May 31, 2029$692,742 - $692,742

A Fail Safe, High Output Failing Fontan Pump

open

Feb 28, 2027$320,838 - $320,838

Pulse-oximetry method for un-biased assessment of arterial saturation

open

Jun 30, 2030$134,537 - $134,537

The Impact of Positive Airway Pressure (PAP) Therapy on Myocardial Blood Flow in Adults with Obstructive Sleep Apnea at High-Risk of Cardiovascular Disease: The PAP-Flow Study

open

Aug 31, 2030$173,556 - $173,556

B cells as boostable factories for HIV inhibition

open

Jun 30, 2030$516,986 - $516,986

ENHANCE: Enhancing Nutrition in Home-visiting programs to Advance PareNt-Child health

open

Aug 31, 2027$841,555 - $841,555

Translational development and clinical evaluation of a bioengineered human lung graft for clinical transplantation

open

Jun 30, 2027$1,266,937 - $1,266,937

Electrocardiogram-Based Deep Learning Prediction of Coronary Artery Calcium and Adverse Cardiovascular Outcomes in South Asians.

open

Sep 6, 2027$76,819 - $76,819

Active, Nourished, and Empowered Teens (ANET): Co-Development of a Modular Nutrition and Fitness Intervention for Community Youth

open

Jun 30, 2030$195,696 - $195,696

Structure, function, and mechanobiology of a compression-sensitive cell-cell junction

open

May 31, 2029$644,180 - $644,180

The Role of Neutrophils in Cystic Fibrosis Pathogenesis

open

Aug 31, 2027$1,074,576 - $1,074,576

Novel mechanisms of macrophage foam cell formation.

open

Aug 31, 2027$129,600 - $129,600

BK channels in Cardiac physiology

open

Jun 30, 2029$694,466 - $694,466

Localized Chelation Therapy for Removing Calcification in PAD

open

Jun 30, 2029$689,928 - $689,928

Sexually Dimorphic Mechanisms in Human Thoracic Aortic Aneurysm.

open

Jun 30, 2029$733,439 - $733,439

The Role of Glycans in Influenza A Virus Mucosal Trapping

open

Sep 7, 2027$37,289 - $37,289

Exploring the mechanism by which defects in the PIX signaling pathway result in cardiomyopathy

open

Sep 7, 2028$49,538 - $49,538

Investigating the Formation and Remodeling of Uterine Spiral Arteries during Pregnancy

open

Nov 7, 2026$37,553 - $37,553

Social Determinants of Symptoms in Preschool Children with Recurrent Wheezing

open

May 31, 2029$690,473 - $690,473

The role of the small GTPase Rap1 and environmental cues in the regulation of adhesion and cytoskeletal dynamics in migrating platelets

open

Sep 8, 2029$41,171 - $41,171

Sex-dependent regulation of cardiac cAMP, ECC, and arrhythmia by phosphodiesterases

open

May 31, 2029$650,028 - $650,028

Clinical Evaluation of an Alarm Activated Detection System to Enable Early Intervention of Emerging Respiratory Decline with the Linshom Medical Continuous Predictive Respiratory Sensor (CPRS)

open

Aug 31, 2027$322,277 - $322,277

Cardiac function and proteomic biomarkers in individuals with perinatal HIV infection or exposure

open

Jun 30, 2030$571,021 - $571,021

Prior Glucagon-like Peptide-1 Receptor Agonist Therapy and Pregnancy, Postpartum, and Child Cardiovascular Outcomes: A Target Trial

open

May 31, 2029$772,581 - $772,581

Small intestinal remodeling across pregnancy cycles

open

Aug 31, 2028$1,525,500 - $1,525,500

Molecular Imaging of Atherosclerosis in Peripheral Artery Disease

open

May 31, 2029$700,019 - $700,019

The Role of Developmental Dysanapsis in Lung Development Throughout the Lifespan in Experimental Bronchopulmonary Dysplasia

open

Aug 31, 2027$106,391 - $106,391

Optimizing dietary adherence in a mobile behavioral weight loss intervention for adults

open

Jun 30, 2030$766,277 - $766,277

Track 1 NIH MD/PhD FM1 Application for Loh

open

Sep 9, 2029$54,538 - $54,538

Deciphering respiratory disease mechanisms through integration of genomic and functional data across massive global biobanks

open

Jun 30, 2030$805,921 - $805,921

SPECIFIC REGULATION OF CARDIAC ATRIAL CONTRACTILITY

open

Jun 30, 2030$643,843 - $643,843

FcgR-activated neutrophil regulation of T cells in nephritis and vasculitis

open

Aug 31, 2026$300,000 - $300,000

Real-Time Continuous Troponin Monitoring: A Breakthrough in Personalized Cardiovascular Risk Assessment and Management

open

Oct 31, 2026$349,734 - $349,734

Genetic Regulation of Gene Expression in Hispanic/Latino Cord Blood Samples

open

Aug 31, 2027$262,159 - $262,159

Imaging the Respiratory Effects of Truncal Adiposity in Acute Hypoxemic Respiratory Failure

open

Jun 30, 2030$700,857 - $700,857

Transitional Alveolar Epithelial Cells in Normal Lung Development

open

Jun 30, 2029$637,913 - $637,913

Development and Validation of a High-Fidelity Cardiac Presurgical Planning Platform for Congenital Heart Defects Using 3D Printing Technology

open

Sep 9, 2026$400,016 - $400,016

The role of GPI-anchor biosynthesis in sleep regulation

open

Jun 30, 2029$755,257 - $755,257

Effects of Surgical Removal of Uterine Fibroids on Atherosclerotic Cardiovascular Disease

open

Sep 10, 2026$49,538 - $49,538

Radon Asthma Intervention Trial (ROME)

open

Aug 31, 2030$784,318 - $784,318

Vagal and spinal afferent mapping of rat and human hearts in health and disease

open

Jun 30, 2030$726,035 - $726,035

Michigan Emergency Medicine Physician-Scientist StARR Training Program

open

Jun 30, 2030$207,342 - $207,342

The Role of Rheology and Transfusion on Microvascular Thrombosis in Sepsis

open

Aug 31, 2027$110,635 - $110,635

HEG1 as a regulator of hypertension and atherosclerosis

open

Sep 11, 2027$78,040 - $78,040

Chromatin Regulation of Immune Cells in Myocardial Inflammation

open

May 31, 2030$803,768 - $803,768

Defining the molecular basis of thrombospondin-1-induced fibro-fatty diaphragm remodeling--a driver of obesity-associated respiratory dysfunction

open

Jun 30, 2030$518,613 - $518,613

Defining the function of C/EBP-beta and its downstream target PSMB9 in atherosclerosis

open

Sep 11, 2027$81,040 - $81,040

Epigenomic mechanisms of cardiac fibrosis and heart failure

open

May 31, 2029$811,885 - $811,885

Coronary Atherosclerotic Burden in AsA-NHPI: the Role of the Gut Microbiome

open

Jun 30, 2029$2,177,784 - $2,177,784

Epithelial cell mediated fibroblast activation through CTHRC1-TGFb signaling in fibrotic lung diseases

open

Aug 31, 2027$107,752 - $107,752

Using a community-engaged approach to design and pilot-test an intervention aimed at reducing ultra-processed food consumption in preschool children to improve cardiovascular health

open

Jun 30, 2030$166,968 - $166,968

Developing Innovative Cell and Gene Therapy Strategies to Treat Fanconi Anemia

open

Jun 30, 2030$662,949 - $662,949

Promoting Asthma Guidelines and Management through Technology-Based Intervention and Care Coordination in Clinics and Schools (PRAGMATIC-S)

open

Jun 30, 2030$771,750 - $771,750

Assessment of Dissolved Phase 129Xe as a Biomarker for gas-exchange and vascular function in asthma

open

Jun 30, 2029$461,115 - $461,115

NHLBI RECOVER Cybersecurity Program

open

Sep 14, 2026$1,214,646 - $1,214,646

Junctophilin-2 in Cardiac Fibroblasts

open

May 31, 2029$651,009 - $651,009

Jackson Heart Study (JHS) Training and Education Center Renewal

open

Sep 14, 2026$1,122,619 - $1,122,619

Genetically Linked Metabolites of Sepsis Severity and Mortality

open

Aug 31, 2027$256,785 - $256,785

SCH: Real-Time Evaluation of Acute Myocardial Infarction with Multi-Lead ECG Monitoring from Wearable PPG Measurements

open

Jun 30, 2029$300,000 - $300,000

1/2 Randomized comparison of the Outcomes of single vs Multiple Arterial grafts trial in Women (ROMA:Women)

open

Aug 31, 2026$1,048,249 - $1,048,249

Integrated Intervention for Depression and Asthma Self-management in Older Adults

open

Aug 31, 2028$259,752 - $259,752

Role of MMP3 in cardiac microvascular barrier dysfunction and heart failure during sepsis

open

Jun 30, 2029$762,950 - $762,950

Neighborhood context and sleep in early childhood

open

Aug 30, 2027$254,250 - $254,250

The Role of Cell-Specific PD-L1 in cardiac pathophysiology post Ischemic Injury and Cancer

open

May 31, 2030$425,505 - $425,505

More heart transplants through informed donor selection

open

Aug 31, 2030$165,672 - $165,672

Hypoxemia with Sleep in Sickle Cell Anemia-Prevalence, Clinical and Cellular Impact & Response to Therapy: A Multi-Site Prospective Study Accessing New Collaborative Pathways

open

Jun 30, 2029$761,028 - $761,028

Evaluating the efficacy of computer aided exercise stress ECG reader (CAESER) for automated diagnosis of coronary artery disease

open

Aug 31, 2027$252,676 - $252,676

Manufacturing and Analytical Validation of the Microfluidic Impedance Red Cell Assay (MIRCA) for Commercial Viability

open

Jun 30, 2028$312,371 - $312,371

TREM-1 therapy for the treatment of empyema

open

Aug 30, 2026$457,954 - $457,954

1/2 WIN Ratio Analysis to Determine a Strategy of Non-Invasive SUpport for Respiratory Failure in the EmeRgency Department (WINDSURFER)

open

Aug 31, 2026$1,535,439 - $1,535,439

Endovascular Suturing Device for Augmentation of Endograft Fixation During Endovascular Repair of Abdominal Aortic Aneurysm to Reduce Reinterventions Due to Endograft Migration or Type 1a Endoleak

open

May 31, 2027$1,364,080 - $1,364,080

MRI of epicardial adipose tissue composition: development of methods and application to heart failure with preserved ejection fraction

open

Aug 31, 2029$802,611 - $802,611

Proof of concept and dose response of CAM-6019 for HFrEF patients

open

Sep 11, 2026$2,095,748 - $2,095,748

Novel protein biomarkers of youth-onset type 2 diabetes

open

Jun 30, 2030$693,964 - $693,964

Endothelial Inflammation, Src Kinase Dysregulation, and Fibrosis in Early Pulmonary Arterial Hypertension

open

Jun 30, 2030$800,962 - $800,962

Development of PAR2 Pepducins for the Treatment of COPD

open

Oct 31, 2026$468,369 - $468,369

Targeting Trem2 in Atherosclerosis Progression

open

Sep 14, 2028$37,073 - $37,073

JHS TRAINING AND EDUCATION CENTER NHLBI FUNDING 9/15/2025 - 9/14/2026

open

Sep 14, 2026$1,439,525 - $1,439,525

Interrogating the pathogenesis of COPD using metabolomics and genomics data

open

May 31, 2029$800,679 - $800,679

Rescue anakinra treatment for moderate asthma attacks

open

Aug 31, 2028$233,250 - $233,250

JHS Training and Education Center NHLBI Funding

open

Sep 14, 2026$370,373 - $370,373

CArdiometabolic riSk and Comorbidities in Adults with Down syndrome- Electronic Health Record Examination (CASCADE)

open

Aug 31, 2027$370,096 - $370,096

Jackson Heart Study (JHS) Community Engagement Center (CEC): Task Area A

open

Sep 14, 2035$936,997 - $936,997

Promoting child respiratory health through novel psychosocial targets: An investigation of a maternal mental health intervention

open

Jun 30, 2029$92,790 - $92,790

Protein Aggregation in Hematopoietic Stem Cells

open

Jun 30, 2029$536,468 - $536,468

Role of pathologic fibroblast subsets unique to silicosis

open

Jun 30, 2030$638,900 - $638,900

PET imaging of Chemotherapy-Induced Cardiotoxicity

open

Aug 31, 2029$768,567 - $768,567

Targeting the Pathophysiology of Sickle Cell-Related Kidney Disease Using SGLT2 Inhibitors

open

Jun 30, 2030$755,853 - $755,853

SleepFlex head and neck exercise program for the treatment of mild to moderate obstructive sleep apnea

open

Aug 30, 2026$583,718 - $583,718

PACE-VT: A Non-Invasive, Machine-Learning-Driven Digital Twin Approach for Precise Targeting of Ventricular Tachycardia in Cardiac Stereotactic Body Radiotherapy

open

Aug 31, 2027$232,500 - $232,500

Personalized oxygen therapy for critically ill adults: a randomized trial

open

Aug 31, 2026$874,997 - $874,997

A New-Generation Lipid-Lowering and Anti-Inflammatory siRNA Therapy for Atherosclerosis

open

Jun 30, 2029$787,453 - $787,453

Investigating pulmonary ionocyte function and development using iPSCs

open

Jun 30, 2030$809,162 - $809,162

Short-Range Spread of Cytokines: Generality, Dynamics, and Impact on Population Variability

open

Jun 30, 2030$570,814 - $570,814

Neutral sphingomyelinase in the mechanical regulation of the heart

open

Jun 30, 2029$639,822 - $639,822

Noninvasive Phenotyping of Respiratory Function in People with Muscular Dystrophies Using Electrical Impedance Tomography

open

Jun 30, 2030$655,885 - $655,885

Leveraging Large-Scale Multi-Ethnic, Multi-Omic Data for Functional Analysis of Central Obesity Loci

open

Jun 30, 2029$732,261 - $732,261

Uncovering the Roles of PIP5KDuring Cell Migration

open

Sep 14, 2027$49,538 - $49,538

HEARTSHARE AMP HF SAMPLE PROCESSING FOR TOPMED MULTI-OMICS

open

Sep 14, 2026$157,459 - $157,459

ADS BPA TASK ORDER 2 PUBLIC WEBSITE DEVELOPMENT AND MAINTENANCE

open

Sep 14, 2026$1,183,729 - $1,183,729

Mobile-based Obstetric Monitoring for Pregnancies Complicated by Hypertension and/or Diabetes (MOM-HD): a Type II Hybrid Implementation-Effectiveness Trial

open

May 31, 2030$465,472 - $465,472

Jackson Heart Study (JHS) Coordinating Center: Task Area A - Core Study Operations

open

Sep 14, 2035$3,791,131 - $3,791,131

Posttranslational control of VSMC identity and vascular health

open

Jun 30, 2029$766,667 - $766,667

PEG Hydrogels to Investigate the Role of Vasa Vasorum Angiogenesis in Tissue Engineered Vascular Grafts

open

Sep 14, 2027$75,052 - $75,052

Identification of Biomarkers of Plant-Rich Diets and Carbonyl Stress and Their Associations with Cardiovascular Risk

open

Jun 30, 2030$733,785 - $733,785

Community Vital Signs (CVS): An integrated community-based approach to identify undiagnosed hypertension in Nigeria

open

Feb 28, 2029$344,742 - $344,742

1/2 ASTRO: Adjuvant STeRoid Outcomes in idiopathic subglottic stenosis: A randomized trial

open

Aug 31, 2026$1,314,743 - $1,314,743

Unraveling idiopathic pulmonary fibrosis endophenotypes; a lung-centric approach to prognostic and therapeutic biomarker validation

open

Jun 30, 2030$718,002 - $718,002

Assessing and Decomposing Drivers of Disparities in Cardiovascular Health Outcomes in Sexual Minorities

open

Jun 30, 2027$259,729 - $259,729

Deciphering the Molecular Mechanism of Pediatric Interstitial Lung Disease to Advance Targeted Therapies

open

Jun 30, 2030$629,498 - $629,498

A cell-permeable peptide therapeutic to reduce myocardial reperfusion injury

open

Aug 31, 2026$388,036 - $388,036

Cardiomyocyte-fibroblast signaling in atrial fibrillation

open

Jun 30, 2029$72,980 - $72,980

AssuranceET: a novel endotracheal tube sealing mechanism to protect pediatric patients from airway trauma and collapse while empowering clinician decision-making.

open

Aug 31, 2026$305,218 - $305,218

Optimal physical activity timing and 24-hour activity composition for prevention of hypertensive disorders of pregnancy

open

Jun 30, 2030$751,124 - $751,124

Toward Artificial Intelligence-enabled Automatic Echocardiography Reporting: A Study of Visual-Linguistic Foundation Model Frameworks

open

Aug 31, 2030$188,136 - $188,136

Environmental Predictors of Treatment Responsiveness for Pediatric Acute Asthma Exacerbations

open

Aug 31, 2027$189,000 - $189,000

The non-canonical roles of NIPBL in cardiomyocytes

open

Jun 30, 2030$706,519 - $706,519

Novel Myofunctional Nipple to Prevent Obstructive Sleep Apnea in Infants

open

Aug 30, 2026$316,609 - $316,609

Bilevel positive airway pressure (BPAP) for severe pediatric asthma exacerbations: A randomized, controlled trial.

open

Aug 31, 2027$427,256 - $427,256

Improving understanding of sleep apnea pathogenesis using novel imaging techniques during sleep

open

Jul 31, 2029$782,473 - $782,473

Novel Plasmin-independent Thrombolytic Agent for Pulmonary Embolism

open

Aug 31, 2026$499,882 - $499,882

Emergency Granulopoiesis in Ventricular Remodeling

open

Jun 30, 2030$728,529 - $728,529

A Novel, Low-Cost, Machine Learning based and Wearable Technology for Monitoring Heart Failure Parameters

open

Aug 31, 2028$406,221 - $406,221

Precision Lead Delivery for Advanced Conduction System Pacing

open

Aug 31, 2026$313,302 - $313,302

Jackson Heart Study (JHS) Field Center

open

Sep 14, 2026$3,819,327 - $3,819,327

Mechanisms of cardioprotective Y RNA signaling in macrophages

open

Jun 30, 2030$694,252 - $694,252

SCH: Advancing Public Health Intervention with Data-driven Restless Multi-Armed Bandit Framework

open

Jun 30, 2029$299,996 - $299,996

Funder Overview

Total Opportunities1000

Grants1000

Contracts0

Track this funder

Start Free Trial

National Heart Lung and Blood Institute

About

Grants (1000)

Frontiers at the edge: Subpleural fibroblasts orchestrate pulmonary fibrosis progression

Screening and validation of miRNA targets for neurogenic hypertension.

Biomarkers and Predictors of Treatment Response in Chronic Anemia in Sickle Cell Disease

Genomic and Clinical Mechanisms and Prognostic Implications of Myocardial Lipomatous Metaplasia

Mapping Activated Microglia and Their Effect on Cognitive Deficits in Adults with Sickle Cell Disease

Comparative vertebrate neural crest contribution to the hematopoietic stem cell specification niche

Immunogen Core

Kir2.1 channel dysfunction underlies neurovascular coupling impairment in autism

Decoding the gene regulatory network of mammalian cardiac maturation

Unraveling Endothelial-CardiomyocyteCrosstalk in Cardiomyopathy: An Integrated Multimodal Approach

Mechanisms of SP-A and Its Genetic Variants in Regulating Lung Innate Immunity

Visualizing Sodium in Lymphatic Disease: a Translational Path

Novel pathways and mechanisms underlying disorders of platelet count and/or function

Elucidating the role of the tunica adventitia resident progenitor cells in vascular calcification

Pain phenotypes in advanced peripheral arterial disease

Role of TRPM7-Mediated Signaling in Vascular Remodeling in Abdominal Aortic Aneurysm

Exploring the Molecular Landscape of Lung Health and Aging Through a Multi-Omics Lens

Dynamics and plasticity of the hematopoietic stem cell niche

Developing cardiac organoids with deliberate heterogeneity for modeling sinus node dysfunction

Fatty Acid Metabolic Drivers of Right Ventricular Dysfunction in Heart Failure Associated Pulmonary Hypertension

Discovery of rare splicing variants in whole blood and lung

Regional Disparity of Skeletal Muscle Microvascular Dysfunction in Systolic Heart Failure

Role of Gasdermin-D in neonatal hyperoxia-induced systemic vascular remodeling and cardiac dysfunction

High-energy human milk diets in the first two weeks after birth to reduce the severity of respiratory morbidity in extremely preterm infants

Hemogenic mesoderm heterogeneity, regulation, and function

In-vivo and Ex-vivo Analysis of Tissue S-nitrosothiols in Sepsis

TGFß signaling in the pathogenesis of lymphangioleiomyomatosis

Whole genome sequence interpretation for lipids to discover new genes and mechanisms for coronary artery disease

Modeling the Effect of Apolipoprotein LI Risk Variants on CVD Risk in African American E-cigarette Users Using Human Induced Pluripotent Stem-Cell-Derived Endothelial Cells

Mechanism of ketogenic diet-induced hypercholesterolemia

High-resolution phenotyping of the hemodynamic consequences of thoracic aortic aneurysm repair

The protein C pathway: Mechanisms, Structure-function, and Translation

Integrative Single-Cell Analysis of Aging-Associated Changes in Human Hematopoietic Stem Cell Heterogeneity

Early Immune Signatures of COPD: Linking Inflammation to Disease Progression

Longitudinal Examination of Food Insecurity and Cardiometabolic Health Risk in Hispanic/Latino Adolescents

ARDVARC-Advancing Rare Disorders: Vascular mAlformation Research Network with CaNVAS: Career Core

PSAT1 modified mRNA induces cardiac repair post-ischemic heart injury

Dissecting the role of vascular endothelial BMP9 signaling in lung transplantation

Molecular Analysis of Airway Secretory Cells in Health and Disease

Equitable Implementation of Remote Patient Monitoring in Pediatric Invasive Home Mechanical Ventilation Using Wireless Devices

Unraveling The Mechanism of Heart Failure in Hypertrophic Cardiomyopathy with Exercise CMR

Understanding and addressing the lack of and delayed screening for primary Aldosteronism

Analyzing effectiveness of ongoing natural experiments in telehealth

Aerosolized Chemically Modified Tetracycline Nanoformulation for the Treatment of Acute Respiratory Distress Syndrome

Hemostatic erythrocytes for acute non-compressible hemorrhage

Regulation of cardiac metabolism during Leukemia

Establishing the feasibility of measuring bereavement-related stress in a naturalistic setting

Immuno-Metabolic Regulation of Vascular Dysfunction by CD70

EQUITABLE: Equity in Treatment for Asthma Between Latinos and Whites

Precision Prediction of Right Ventricular Size, Function, and Outcomes in Patients with Repaired Tetralogy of Fallot

Deciphering links between Leukocyte Activation and Infections in VAD patients

Development of a Totally Implanted Left Ventricular Assist Device

Molecular and Translational Studies in Hematologic Disorders

Pulmonary Artery Endothelial Cell Endotypes and the Role of Anoikis Resistance in Pulmonary Hypertension

Sequential Multiple Assignment Randomized Trial to Reduce Food Insecurity and Improve Adherence in Patients with Hypertension

Artificial sweeteners and cardiovascular disease

Characterization of the roles of bivalent domains in CD4+ T cell differentiation

Integrated super-resolution CMR-deep learning to deconvolute passive and active causes of impaired relaxation

Reprogrammed Monocytes Improve Neovascularization in Peripheral Arterial Disease

Targeting Hypoxia-Inducible Factors (HIFs) for Heart and Lung Disease

Novel Insights into the Mechanistic Role of Small Rho GTPase in Chronic Cardiac Fibrotic Remodeling

Role of cardiac m6A methyltransferases

RNA methylation in the progress of heart failure

Neuroinflammation as a mediator of the exaggerated Piezo2 and Exercise Pressor Reflex in Peripheral Artery Disease

Hypertension, antihypertensive treatment, and uterine fibroid diagnosis in an integrated healthcare system

Investigating fibrinogen as a pathologic and targetable mediator of COVID-19-associated coagulopathy

Medial Arterial Calcification in Peripheral Artery Disease

Focal Myocardial Delivery of Small Molecule Nitroalkenes using Ultrasound Targeted Microbubble Cavitation to Improve Ventricular Recovery Following Myocardial Infarction

Phenotyping Net Immune State with MicroRNAs in Cardiac Transplantation

G6PD Deficiency and Atherosclerosis

Assessing myocardial fibrosis with spin locked MRI

Secondary Analysis of 3D Echo Images of the Right Ventricle to Compute 3D Surface Strain

Junctophilin-1 in the heart

Optimizing Effectiveness and Implementation of COPD Self-Management Treatment

Receptor-mediated Control of Pulmonary Ionocytes

Impact of prenatal exposures to copper from electronic nicotine delivery system (ENDS) aerosols on the immature neonatal pulmonary immune system and IL-10-mediated asthmatic responses

Applying reinforcement learning to create a precision medicine weight loss intervention